scholarly journals Effects of linker and liposome anchoring on lactose-functionalized glycomacromolecules as multivalent ligands for binding galectin-3

RSC Advances ◽  
2019 ◽  
Vol 9 (41) ◽  
pp. 23484-23497 ◽  
Author(s):  
Tanja Freichel ◽  
Dominic Laaf ◽  
Miriam Hoffmann ◽  
Patrick B. Konietzny ◽  
Viktoria Heine ◽  
...  
Keyword(s):  
High Avidity ◽  
Multivalent Ligands ◽  
Galectin 3

We combine multivalent presentation of glycan ligands on sequence-defined oligo(amidoamines) and liposomes to achieve high avidity ligands targeting galectin-3.

Protective role of peroxiredoxin-4 in heart failure

2020 ◽  
Vol 134 (1) ◽  
pp. 71-72
Author(s):  
Naseer Ahmed ◽  
Masooma Naseem ◽  
Javeria Farooq
Keyword(s):  
Heart Failure ◽  
Cardiac Fibroblasts ◽  
Protective Role ◽  
Oxidative Stress Markers ◽  
Stress Markers ◽  
Total Antioxidant ◽  
Galectin 3 ◽  
Consequent Increase ◽  
And Oxidative Stress

Abstract Recently, we have read with great interest the article published by Ibarrola et al. (Clin. Sci. (Lond.) (2018) 132, 1471–1485), which used proteomics and immunodetection methods to show that Galectin-3 (Gal-3) down-regulated the antioxidant peroxiredoxin-4 (Prx-4) in cardiac fibroblasts. Authors concluded that ‘antioxidant activity of Prx-4 had been identified as a protein down-regulated by Gal-3. Moreover, Gal-3 induced a decrease in total antioxidant capacity which resulted in a consequent increase in peroxide levels and oxidative stress markers in cardiac fibroblasts.’ We would like to point out some results stated in the article that need further investigation and more detailed discussion to clarify certain factors involved in the protective role of Prx-4 in heart failure.

Hostile attribution is associated with increased galectin-3 in heart failure patients

2013 ◽  
Author(s):  
Wawrzyniak Andrew J. ◽  
Kerry S. Whittaker ◽  
Sarah M. Godoy ◽  
Kristie M. Harris ◽  
Maria N. Banis ◽  
...  
Keyword(s):  
Heart Failure ◽  
Hostile Attribution ◽  
Heart Failure Patients ◽  
Galectin 3

Galectin-3 vermindert die akute und chronische DSS-Kolitis bei Mäusen

2008 ◽  
Vol 46 (10) ◽  
Author(s):  
E Lippert ◽  
M Stieber-Gunckel ◽  
C Hofmann ◽  
N Dunger ◽  
W Falk ◽  
...  
Keyword(s):  
Galectin 3

Galectin-3 and Aldosterone as Potential Tandem Biomarkers in Pulmonary Arterial Hypertension

2016 ◽  
Vol 64 (S 02) ◽  
Author(s):  
L. Calvier ◽  
E. Legchenko ◽  
L. Grimm ◽  
H. Sallmon ◽  
A. Hatch ◽  
...  
Keyword(s):  
Pulmonary Arterial Hypertension ◽  
Arterial Hypertension ◽  
Galectin 3 ◽  
Pulmonary Arterial

Evaluation der kardialen Biomarker Galectin-3 und ST2 (IL1RL1) bei Patienten mit beginnender degenerativer Mitralklappenerkrankung (CHIEF B)

2019 ◽  
Author(s):  
S. Klein ◽  
I. Nolte ◽  
E.-M. Packeiser ◽  
N. Iwanuk ◽  
K. Rumstedt ◽  
...  
Keyword(s):  
Galectin 3

Galectin–3 wird in Fisteln, Stenosen und Makrophagen bei Morbus Crohn vermindert exprimiert

2005 ◽  
Vol 43 (10) ◽  
Author(s):  
E Lippert ◽  
F Bataille ◽  
M Hausmann ◽  
S Kellermeier ◽  
W Falk ◽  
...  
Keyword(s):  
Morbus Crohn ◽  
Galectin 3

Galectin-3 induziert die Migration intestinaler Fibroblasten

2006 ◽  
Vol 44 (08) ◽  
Author(s):  
E Lippert ◽  
J Brenmoehl ◽  
W Falk ◽  
J Schölmerich ◽  
G Rogler
Keyword(s):  
Galectin 3
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