scholarly journals Remarkably selective biocompatible turn-on fluorescent probe for detection of Fe3+ in human blood samples and cells

RSC Advances ◽  
2019 ◽  
Vol 9 (47) ◽  
pp. 27439-27448 ◽  
Author(s):  
Vishaka V. H. ◽  
Manav Saxena ◽  
Geetha Balakrishna R. ◽  
Sachin Latiyan ◽  
Shilpee Jain
Keyword(s):  
Fluorescent Probe ◽  
Human Blood ◽  
Blood Samples ◽  
Turn On ◽  
Human Blood Samples

The robust nature of a biocompatible fluorescent probe is demonstrated, by its detection of Fe3+ even after repeated rounds of quenching (reversibility) by acetate in real human blood samples and cells in vitro.

scholarly journals Platelet-neutrophil complex formation-a detailed in vitro analysis of murine and human blood samples

2015 ◽  
Vol 99 (5) ◽  
pp. 781-789 ◽  
Author(s):  
Maximilian Mauler ◽  
Julia Seyfert ◽  
David Haenel ◽  
Hannah Seeba ◽  
Janine Guenther ◽  
...  
Keyword(s):  
Complex Formation ◽  
Human Blood ◽  
Blood Samples ◽  
Human Blood Samples ◽  
Vitro Analysis ◽  
In Vitro Analysis

Stability of Fibrinogen Concentrate in Human Blood Samples: An In Vitro Study

2018 ◽  
Vol 183 (suppl_1) ◽  
pp. 183-188 ◽  
Author(s):  
Wenjun Z Martini ◽  
Rodolfo de Guzman ◽  
Michael A Dubick
Keyword(s):  
Human Blood ◽  
In Vitro Study ◽  
Vitro Study ◽  
Fibrinogen Concentrate ◽  
Blood Samples ◽  
Human Blood Samples

scholarly journals Application of microRNA in Human Osteoporosis and Fragility Fracture: A Systemic Review of Literatures

2021 ◽  
Vol 22 (10) ◽  
pp. 5232
Author(s):  
Yen-Zung Wu ◽  
Hsuan-Ti Huang ◽  
Tsung-Lin Cheng ◽  
Yen-Mou Lu ◽  
Sung-Yen Lin ◽  
...  
Keyword(s):  
Human Blood ◽  
Diagnostic Value ◽  
Systemic Review ◽  
Blood Samples ◽  
In Vivo Experiments ◽  
Pubmed Database ◽  
Entry Points ◽  
Human Blood Samples

MicroRNAs (miRNAs) could serve as ideal entry points to the deregulated pathways in osteoporosis due to their relatively simple upstream and downstream relationships with other molecules in the signaling cascades. Our study aimed to give a comprehensive review of the already identified miRNAs in osteoporosis from human blood samples and provide useful information for their clinical application. A systematic literature search for relevant studies was conducted in the Pubmed database from inception to December 2020. We set two essential inclusion criteria: human blood sampling and design of controlled studies. We sorted the results of analysis on human blood samples according to the study settings and compiled the most promising miRNAs with analyzed diagnostic values. Furthermore, in vitro and in vivo evidence for the mechanisms of the identified miRNAs was also illustrated. Based on both diagnostic value and evidence of mechanism from in vitro and in vivo experiments, miR-23b-3p, miR-140-3p, miR-300, miR-155-5p, miR-208a-3p, and miR-637 were preferred candidates in diagnostic panels and as therapeutic agents. Further studies are needed to build sound foundations for the clinical usage of miRNAs in osteoporosis.

Monitoring clinical levels of heparin in human blood samples with an indicator-displacement assay

2015 ◽  
Vol 51 (10) ◽  
pp. 1953-1956 ◽  
Author(s):  
Jean-Patrick Francoia ◽  
Robert Pascal ◽  
Laurent Vial
Keyword(s):  
Human Blood ◽  
Fluorescent Detection ◽  
Blood Samples ◽  
Turn On ◽  
Displacement Assay ◽  
Human Blood Samples ◽  
First Time ◽  
Detection And Quantification

Herein, we report a simple assay – involving the displacement of a new designed dye from a dendrigraft surface – that allows for the first time the turn-ON fluorescent detection and quantification of heparin in human blood at clinically relevant levels.

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