scholarly journals Zonal rotor centrifugation revisited: new horizons in sorting nanoparticles

RSC Advances ◽  
2019 ◽  
Vol 9 (47) ◽  
pp. 27549-27559 ◽  
Author(s):  
Claudia Simone Plüisch ◽  
Brigitte Bössenecker ◽  
Lukas Dobler ◽  
Alexander Wittemann
Keyword(s):  
Large Scale ◽  
New Horizons ◽  
Zonal Rotor

Hollow bowl-shaped rotors allow for efficient fractionation of nanoparticle mixtures at large scale.

Large-scale preparation of synaptosomes from bovine brain using a zonal rotor technique

1979 ◽  
Vol 4 (4) ◽  
pp. 483-504 ◽  
Author(s):  
Kenneth C. Leskawa ◽  
Herbert C. Yohe ◽  
Michiko Matsumoto ◽  
Abraham Rosenberg
Keyword(s):  
Large Scale ◽  
Bovine Brain ◽  
Large Scale Preparation ◽  
Scale Preparation ◽  
Zonal Rotor

scholarly journals Tom Nook, Capitalist or Comrade?

Loading ◽  
2021 ◽  
Vol 13 (22) ◽  
pp. 109-134
Author(s):  
Emma Vossen
Keyword(s):  
Large Scale ◽  
Real Life ◽  
Student Loan ◽  
Online Discussions ◽  
Housing Crisis ◽  
Cultural Significance ◽  
New Horizons ◽  
Hard Times ◽  
The Many ◽  
Hearts And Minds

Many millennial Animal Crossing players will experience the joy of paying off their beautiful three-floor in-game home only to have that joy cut short by the crushing realization that they may never experience homeownership in real life. Who do we then take that anger and disappointment out on? The capitalists with a stranglehold on the housing market? The governments and companies holding our lives hostage for student loan debt? Our landlords who take most of our income each month so we can keep a roof over our heads? Our bosses who are criminally underpaying us for our labour? Or is it a fictional racoon? Arguments about the ethics of Animal Crossing’s non-playable character Tom Nook are inescapable in online discussions about the Animal Crossing series. These discussions generally have two sides: either Tom Nook is a capitalistic villain who exploits the player’s labour for housing, or he is a benevolent landowner who helps the player out in hard times. Vossen first sets the stage by discussing the cultural significance of both the Animal Crossing series, focusing in on Animal Crossing: New Horizons (2020), and the millennial housing crisis. She then examines the many tweets, memes, comics, and articles that vilify Tom Nook (and a few that defend him) and asks: are we really mad at Tom, or are we mad at the cruelty and greed of the billionaires, bosses, and landowners in our real lives? Vossen argues that what she calls “Nook discourse” represents the radical social potential of Animal Crossing to facilitate large-scale real-world conversations about housing, economic precarity, class, and labour that could help change hearts and minds about the nature of wealth.

scholarly journals Wearable Sensors for Monitoring Human Motion: A Review on Mechanisms, Materials, and Challenges

2019 ◽  
Vol 25 (1) ◽  
pp. 9-24 ◽  
Author(s):  
S. Zohreh Homayounfar ◽  
Trisha L. Andrew
Keyword(s):  
Large Scale ◽  
Large Range ◽  
State Of The Art ◽  
Wearable Sensors ◽  
Human Locomotion ◽  
Human Motion ◽  
Human Gait ◽  
Wearable Electronics ◽  
New Horizons ◽  
User Friendly

The emergence of flexible wearable electronics as a new platform for accurate, unobtrusive, user-friendly, and longitudinal sensing has opened new horizons for personalized assistive tools for monitoring human locomotion and physiological signals. Herein, we survey recent advances in methodologies and materials involved in unobtrusively sensing a medium to large range of applied pressures and motions, such as those encountered in large-scale body and limb movements or posture detection. We discuss three commonly used methodologies in human gait studies: inertial, optical, and angular sensors. Next, we survey the various kinds of electromechanical devices (piezoresistive, piezoelectric, capacitive, triboelectric, and transistive) that are incorporated into these sensor systems; define the key metrics used to quantitate, compare, and optimize the efficiency of these technologies; and highlight state-of-the-art examples. In the end, we provide the readers with guidelines and perspectives to address the current challenges of the field.

Basal-lateral membranes from rabbit renal cortex prepared on a large scale in a zonal rotor

1982 ◽  
Vol 692 (1) ◽  
pp. 115-125 ◽  
Author(s):  
Richard D. Mamelok ◽  
Solomon S. Tse ◽  
Katherine Newcomb ◽  
Carolyn L. Bildstein ◽  
Dorothy Liu
Keyword(s):  
Large Scale ◽  
Renal Cortex ◽  
Zonal Rotor

Risk and Resilience in Development

2013 ◽  
Author(s):  
Ann S. Masten
Keyword(s):  
Adaptive Systems ◽  
Large Scale ◽  
New Technologies ◽  
Children And Youth ◽  
Risk And Resilience ◽  
Positive Adaptation ◽  
New Horizons ◽  
Core Concepts ◽  
Multiple Levels ◽  
Resilience Science

Findings from five decades of research on risk and resilience in children and youth are highlighted in this chapter, with a focus on positive adaptation in the context of conditions that could pose a significant threat to function or development. The origins of developmental research on risk and resilience are briefly reviewed, followed by definitions of core concepts, and an overview with illustrations of central models that have guided this body of work. Findings on promotive and protective factors for resilience across diverse studies of children and youth show striking consistency, suggesting that fundamental adaptive systems support and protect human adaptation and development in the context of adversity. Exciting new technologies and scientific advances in molecular genetics, neuroscience, and the methods for studying dynamic, interdependent systems have opened new horizons for research on risk and resilience. The rising wave of future resilience science is focused on multiple levels of analysis and their integration, ranging from neurobiological processes of resilience to preparations for surviving large-scale disasters.

scholarly journals Bundle analytics, a computational framework for investigating the shapes and profiles of brain pathways across populations

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Bramsh Qamar Chandio ◽  
Shannon Leigh Risacher ◽  
Franco Pestilli ◽  
Daniel Bullock ◽  
Fang-Cheng Yeh ◽  
...  
Keyword(s):  
Large Scale ◽  
Brain Connectivity ◽  
Medical Data ◽  
Group Differences ◽  
Computational Framework ◽  
Significant Group ◽  
New Horizons ◽  
Progression Markers ◽  
Anatomical Information

Abstract Tractography has created new horizons for researchers to study brain connectivity in vivo. However, tractography is an advanced and challenging method that has not been used so far for medical data analysis at a large scale in comparison to other traditional brain imaging methods. This work allows tractography to be used for large scale and high-quality medical analytics. BUndle ANalytics (BUAN) is a fast, robust, and flexible computational framework for real-world tractometric studies. BUAN combines tractography and anatomical information to analyze the challenging datasets and identifies significant group differences in specific locations of the white matter bundles. Additionally, BUAN takes the shape of the bundles into consideration for the analysis. BUAN compares the shapes of the bundles using a metric called bundle adjacency which calculates shape similarity between two given bundles. BUAN builds networks of bundle shape similarities that can be paramount for automating quality control. BUAN is freely available in DIPY. Results are presented using publicly available Parkinson’s Progression Markers Initiative data.

scholarly journals Stratospheric observations of noctilucent clouds: a new approach in studying middle- and large-scale mesospheric dynamics

2020 ◽  
Vol 38 (1) ◽  
pp. 61-71 ◽  
Author(s):  
Peter Dalin ◽  
Nikolay Pertsev ◽  
Vladimir Perminov ◽  
Denis Efremov ◽  
Vitaly Romejko
Keyword(s):  
High Resolution ◽  
Gravity Wave ◽  
Large Scale ◽  
Spatial Dynamics ◽  
Noctilucent Clouds ◽  
Final State ◽  
New Horizons ◽  
Geographic Coverage ◽  
Cold Area ◽  
Wide Angle Lens

Abstract. The Stratospheric Observations of Noctilucent Clouds (SONC) experimental campaign was conducted on the night of 5–6 July 2018 with the aim of photographing noctilucent clouds (NLCs) and studying their large-scale spatial dynamics at scales of 100–1450 km. An automated high-resolution camera (equipped with a wide-angle lens) was lifted by a stratospheric sounding balloon to 20.4 km altitude above the Moscow region in Russia (∼56∘ N, 41∘ E), taking several hundreds of NLC images during the flight that lasted 1.7 h. The combination of a high-resolution camera and large geographic coverage (∼1500 km) has provided a unique technique of NLC observations from the stratosphere, which is impossible to currently achieve from either the ground or space. We have estimated that a horizontal extension of the NLC field as seen from the balloon was about 1450×750 km, whereas it was about 800×550 km as seen from the ground. The NLC field was located in a cold area of the mesopause (136–146 K), which was confirmed by satellite measurements. The southernmost edge of the NLC field was modulated by partial ice voids of 150–250 km in diameter. A medium-scale gravity wave had a wavelength of 49.4±2.2 km and an amplitude of 1.9±0.1 km. The final state of the NLC evolution was represented by thin parallel gravity wave stripes. Balloon-borne observations provide new horizons in studies of NLCs at various scales from metres to thousands of kilometres. Here we present a review paper on our experiment describing the initial results. Detailed studies on the time evolution of the cloud movements will be done in the future.

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