scholarly journals Mesoporous bioactive glass nanoparticles doped with magnesium: drug delivery and acellular in vitro bioactivity

RSC Advances ◽  
2019 ◽  
Vol 9 (22) ◽  
pp. 12232-12246 ◽  
Author(s):  
Zakaria Tabia ◽  
Khalil El Mabrouk ◽  
Meriame Bricha ◽  
Khalid Nouneh
Keyword(s):  
Drug Delivery ◽  
Simulated Body Fluid ◽  
Body Fluid ◽  
Drug Loading ◽  
In Vitro Bioactivity ◽  
Magnesium Doping ◽  
Biomineralization Process ◽  
Binary Glass ◽  
Mesoporous Bioactive Glass

The effects of the magnesium doping of binary glass (Si–Ca) on particle texture, on the biomineralization process in simulated body fluid (SBF) as well as on drug loading and release were examined.

Synthesis of sol-gel derived glass powder and in vitro bioactivity property tested in simulated body fluid

2016 ◽  
Author(s):  
S. A. Syed Nuzul Fadzli ◽  
S. Roslinda ◽  
Firuz Zainuddin ◽  
Hamisah Ismail
Keyword(s):  
Simulated Body Fluid ◽  
Body Fluid ◽  
Glass Powder ◽  
Sol Gel ◽  
In Vitro Bioactivity

scholarly journals Electrochemical Corrosion and In Vitro Bioactivity of Nano-Grained Biomedical Ti-20Nb-13Zr Alloy in a Simulated Body Fluid

Materials ◽  
2017 ◽  
Vol 11 (1) ◽  
pp. 26 ◽  
Author(s):  
Mohamed Hussein ◽  
Madhan Kumar ◽  
Robin Drew ◽  
Nasser Al-Aqeeli
Keyword(s):  
Simulated Body Fluid ◽  
Body Fluid ◽  
Electrochemical Corrosion ◽  
In Vitro Bioactivity ◽  
13Zr Alloy

Studies on Development, Bioactivity and Corrosion Behaviour of Nanostructured Titania/Hydroxyapatite Composite Layer on Cp Ti

2011 ◽  
Vol 471-472 ◽  
pp. 325-330 ◽  
Author(s):  
K. Venkateswarlu ◽  
N. Rameshbabu ◽  
Arumugam Chandra Bose ◽  
V. Muthupandi ◽  
S. Subramanian
Keyword(s):  
Corrosion Resistance ◽  
Simulated Body Fluid ◽  
Body Fluid ◽  
Composite Layer ◽  
In Vitro Bioactivity ◽  
X Ray ◽  
Composite Layers ◽  
Cp Ti ◽  
Nanostructured Titania

Nanostructured titania/hydroxyapatite (HA) composite layer was developed on commercially pure titanium (Cp Ti) implant material by plasma electrolytic processing (PEP) technique in order to improve its bioactivity and corrosion resistance under physiological conditions. The phases present in the developed composite layer were studied by X-ray diffraction (XRD) technique. The surface morphology and thickness of the composite layers were observed by scanning electron microscopy (SEM). The corrosion characteristics of the developed layer were studied by potentiodynamic polarization scan under simulated body fluid (7.4 pH Hanks solution) and simulated osteoclast (4.5 pH) conditions. The in-vitro bioactivity of the composite layers was studied by using Kokubu’s simulated body fluid (SBF) solution. The X-ray diffractograms reveal the presence of anatase TiO2 and HA phases in the developed layer. The SEM results confirm the pore-free morphology of the implant material surface and the thickness of the developed composite layer was observed to be 110 ± 5 µm for 12 min of PEP. The potentiodynamic polarization study shows an improved corrosion resistance and the in-vitro bioactivity test results indicate enhanced apatite forming ability of PEP treated Cp Ti surfaces compared to that of the untreated Cp Ti, under simulated body fluid conditions.

Mechanical Properties and In Vitro Bioactivity of β-Tri Calcium Phosphate, Merwinite Nanocomposites

2011 ◽  
Vol 493-494 ◽  
pp. 582-587 ◽  
Author(s):  
Marziyeh Abbasi-Shahni ◽  
Saeed Hesaraki ◽  
Ali Asghar Behnam-Ghader ◽  
Masoud Hafezi-Ardakani
Keyword(s):  
Mechanical Properties ◽  
Fracture Toughness ◽  
Calcium Phosphate ◽  
Simulated Body Fluid ◽  
Body Fluid ◽  
Sem Analysis ◽  
In Vitro Bioactivity ◽  
Hard Tissue ◽  
Calcium Phosphate Layer

In this study, nanocomposites based on of β-tri calcium phosphate (β-TCP) and 2.5-10 wt% merwinite nanoparticles were prepared and sintered at 1100-1300°c.The mechanical properties were investigated by measuring compressive strength and fracture toughness. Structural properties were evaluated by XRD, TEM and SEM analysis, and the in vitro bioactivity was studied by soaking the samples in simulated body fluid (SBF). The mechanical strength of the sintered samples wereincreased, by increasing the amount of merwinite phase up to 5 wt%, whereas it decreased when the samples were sintered at 1100 and 1200°c. Nanostructured calcium phosphate layer was formed on the surfaces of the nanocomposites within 1 day immersion in simulated body fluid. Because of appropriate mechanical properties the composite is suggested to be used as substitute for hard tissue.

In vitro bioactivity study of TiCaPCO(N) and Ag‐doped TiCaPCO(N) films in simulated body fluid

2015 ◽  
Vol 105 (1) ◽  
pp. 193-203 ◽  
Author(s):  
I.V. Sukhorukova ◽  
A.N. Sheveyko ◽  
Ph. V. Kiryukhantsev‐Korneev ◽  
E.A. Levashov ◽  
D.V. Shtansky
Keyword(s):  
Simulated Body Fluid ◽  
Body Fluid ◽  
In Vitro Bioactivity

Microstructure and in vitro bioactivity of laser-cladded bioceramic coating on titanium alloy in a simulated body fluid

2010 ◽  
Vol 489 (1) ◽  
pp. 211-214 ◽  
Author(s):  
Min Zheng ◽  
Ding Fan ◽  
Xiu-kun Li ◽  
Jian-bin Zhang ◽  
Qi-bin Liu
Keyword(s):  
Titanium Alloy ◽  
Simulated Body Fluid ◽  
Body Fluid ◽  
In Vitro Bioactivity

scholarly journals Is non-buffered DMEM solution a suitable medium for in vitro bioactivity tests?

2014 ◽  
Vol 2 (31) ◽  
pp. 5068-5076 ◽  
Author(s):  
Dana Rohanová ◽  
Aldo Roberto Boccaccini ◽  
Diana Horkavcová ◽  
Pavlína Bozděchová ◽  
Petr Bezdička ◽  
...  
Keyword(s):  
Simulated Body Fluid ◽  
Body Fluid ◽  
Simulated Body Fluid Solution ◽  
Fluid Solution ◽  
In Vitro Bioactivity ◽  
Suitable Medium

For decades the bioactivity of materials has been tested in laboratories by means of in vitro tests under standard ISO 23317 in a Tris-buffered simulated body fluid solution (SBF).

scholarly journals Nghiên cứu tính chất vật liệu thủy tinh y sinh 45S tổng hợp từ nguyên liệu chính cát trắng

2017 ◽  
Vol 33 (2) ◽  
Author(s):  
Bùi Xuân Vương
Keyword(s):  
Simulated Body Fluid ◽  
Cell Viability ◽  
Bioactive Glass ◽  
Body Fluid ◽  
In Vitro Bioactivity ◽  
Melting Method ◽  
Good Cell ◽  
Glass Powders

A bioactive glass 46S6 with composition 46% SiO2 - 24% CaO - 24% Na2O - 6% P2O5 (wt%) was elaborated by melting method. ‘‘In vitro’’ bioactivity of bio-glass was evaluated by soaking of glass-powders in a simulated body fluid (SBF) at different times. The obtained results highlighted the bioactivity of the bio-glass by the formation of a bioactive hydroxyapatite (HA) layer on its surface. Experiments ''in vitro'' in the presence of cells confirmed the non-toxicity and the good cell viability on this bio-glass.

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