Transition metal-free aerobic oxidative cleavage of the C–N bonds of α-amino esters

2019 ◽  
Vol 6 (23) ◽  
pp. 3854-3858
Author(s):  
Shenpeng Tan ◽  
Feng Li ◽  
Soojun Park ◽  
Sanghee Kim
Keyword(s):  
Amino Acid ◽  
Transition Metal ◽  
Metal Catalysts ◽  
Oxidative Cleavage ◽  
Amino Acid Derivatives ◽  
Metal Free ◽  
Amino Esters

A base-mediated aerobic oxidative cleavage of α-amino esters involving a hydroperoxide intermediate was reported, which represents the first example of the cleavage of the α-C–N bonds of amino acid derivatives without the aid of metal catalysts.

The aryne Sommelet–Hauser rearrangement

2019 ◽  
Vol 55 (20) ◽  
pp. 3004-3007 ◽  
Author(s):  
Tony Roy ◽  
Rahul N. Gaykar ◽  
Subrata Bhattacharjee ◽  
Akkattu T. Biju
Keyword(s):  
Amino Acid ◽  
Transition Metal ◽  
Amino Acid Derivatives ◽  
Metal Free

An aryne induced transition-metal-free and mild Sommelet–Hauser rearrangement of tertiary benzylamines for the synthesis of α-aryl amino acid derivatives in moderate to good yields and with broad substrate scope is presented.

scholarly journals Metal-free quinolylation of the primary amino groups of amino acid derivatives and peptides with dihydrooxazolo[3,2-a]quinoliniums

2019 ◽  
Vol 21 (15) ◽  
pp. 4231-4237
Author(s):  
Peng Liu ◽  
Bo Li ◽  
Mengyu Xi ◽  
Zhaoqiang Chen ◽  
Haiguo Sun ◽  
...  
Keyword(s):  
Amino Acid ◽  
Amino Acid Derivatives ◽  
Amino Groups ◽  
Metal Free ◽  
Primary Amino

A new metal-free method for the N-quinolylation of primary amino groups using novel dihydrooxazolo[3,2-a]quinoliniums showing good compatibility with other reactive moieties.

ChemInform Abstract: Transition-Metal-Free Decarboxylation of Dimethyl Malonate: An Efficient Construction of α-Amino Acid Esters Using TBAI/TBHP.

ChemInform ◽  
2015 ◽  
Vol 46 (29) ◽  
pp. no-no
Author(s):  
Jie Zhang ◽  
Ying Shao ◽  
Yaxiong Wang ◽  
Huihuang Li ◽  
Dongmei Xu ◽  
...  
Keyword(s):  
Amino Acid ◽  
Transition Metal ◽  
Amino Acid Esters ◽  
Dimethyl Malonate ◽  
Metal Free ◽  
Efficient Construction ◽  
Acid Esters

Equilibrium and structural studies on transition metal complexes of amino acid derivatives containing the bis(pyridin-2-yl)methyl residue

2001 ◽  
Vol 25 (5) ◽  
pp. 700-706 ◽  
Author(s):  
Katalin Ősz ◽  
Katalin Várnagy ◽  
Imre Sóvágó ◽  
Lídia Lennert ◽  
Helga Süli-Vargha ◽  
...  
Keyword(s):  
Amino Acid ◽  
Transition Metal ◽  
Metal Complexes ◽  
Transition Metal Complexes ◽  
Amino Acid Derivatives ◽  
Structural Studies

scholarly journals Transition-Metal-Free [3+2] Dehydration Cycloaddition of Donor-Acceptor Cyclopropanes With 2-Naphthols

2021 ◽  
Vol 9 ◽  
Author(s):  
Hua Zhao ◽  
Peng Shen ◽  
Dongru Sun ◽  
Hongbin Zhai ◽  
Yufen Zhao
Keyword(s):  
Transition Metal ◽  
Ring Opening ◽  
Metal Catalysts ◽  
Transition Metal Catalysts ◽  
Cyclization Reaction ◽  
Metal Free ◽  
Efficient Access ◽  
Donor Acceptor ◽  
Acid Catalyzed ◽  
Synthetic Application

A Brønsted acid-catalyzed domino ring-opening cyclization transformation of donor-acceptor (D-A) cyclopropanes and 2-naphthols has been developed. This formal [3+2] cyclization reaction provided novel and efficient access to the naphthalene-fused cyclopentanes in the absence of any transition-metal catalysts or additives. This robust procedure was completed smoothly on a gram-scale to afford the corresponding product with comparable efficiency. Furthermore, the synthetic application of the prepared product has been demonstrated by its transformation into a variety of synthetically useful molecules.

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