Chiral helical substituted polyacetylene grafted on hollow polymer particles: preparation and enantioselective adsorption towards cinchona alkaloids

2019 ◽  
Vol 10 (32) ◽  
pp. 4441-4448 ◽  
Author(s):  
Xueyong Yong ◽  
Youping Wu ◽  
Jianping Deng
Keyword(s):  
Cinchona Alkaloids ◽  
Polymer Chains ◽  
Carboxyl Groups ◽  
Polymer Particles ◽  
Helical Polymer ◽  
Enantioselective Adsorption

Hollow polymer particles tethering chiral helical polymer chains and functional carboxyl groups were prepared and applied in enantioselective adsorption.

SuFExable Polymers with Helical Structures Derived from Thionyl Tetrafluoride (SOF4)

2019 ◽  
Author(s):  
Suhua Li ◽  
Gencheng Li ◽  
Bing Gao ◽  
Sidharam P. Pujari ◽  
Xiaoyan Chen ◽  
...  
Keyword(s):  
Functional Polymers ◽  
Polymer Chains ◽  
New Materials ◽  
Helical Structures ◽  
Polymer Backbone ◽  
Silyl Ethers ◽  
Helical Polymer ◽  
Key Characteristics ◽  
Post Modification ◽  
Individual Polymer

The first SuFEx click chemistry synthesis of SOF<sub>4</sub>-derived copolymers based upon the polymerization of bis(iminosulfur oxydifluorides) and bis(aryl silyl ethers) is described. This novel class of SuFEx polymer presents two key characteristics: First, the newly created [-N=S(=O)F-O-] polymer backbone linkages are themselves SuFExable and primed to undergo further high-yielding and precise SuFEx-based post-modification with phenols or amines to yield branched functional polymers. Second, studies of individual polymer chains of several of these new materials indicate the presence of helical polymer structures, which itself suggests a preferential approach of new monomers onto the growing polymer chain upon the formation of the stereogenic linking moiety.

Novel three-dimensional long-term bone marrow culture system using polymer particles with grafted epoxy-polymer-chains supports the proliferation and differentiation of hematopoietic stem cells

2011 ◽  
Vol 236 (11) ◽  
pp. 1342-1350 ◽  
Author(s):  
Yukio Hirabayashi ◽  
Yoshihiro Hatta ◽  
Jin Takeuchi ◽  
Isao Tsuboi ◽  
Tomonori Harada ◽  
...  
Keyword(s):  
Stromal Cells ◽  
Culture System ◽  
3D Structure ◽  
Three Dimensional ◽  
Hematopoietic Cells ◽  
3D Culture ◽  
Polymer Chains ◽  
Polymer Particles ◽  
Hematopoietic Stem ◽  
3D Culture System

Hematopoiesis occurs in the bone marrow, where primitive hematopoietic cells proliferate and differentiate in close association with a three-dimensional (3D) hematopoietic microenvironment composed of stromal cells. We examined the hematopoietic supportive ability of stromal cells in a 3D culture system using polymer particles with grafted epoxy polymer chains. Umbilical cord blood-derived CD34+ cells were co-cultivated with MS-5 stromal cells. They formed a 3D structure in the culture dish in the presence of particles, and the total numbers of cells and the numbers of hematopoietic progenitor cells, including colony-forming unit (CFU)-Mix, CFU-granulocyte-macrophage, CFU-megakaryocyte and burst-forming unit-erythroid, were measured every seven days. The hematopoietic supportive activity of the 3D culture containing polymer particles and stromal cells was superior to that of 2D culture, and allowed the expansion and maintenance of hematopoietic progenitor cells for more than 12 weeks. Various types of hematopoietic cells, including granulocytes, macrophages and megakaryocytes at different maturation stages, appeared in the 3D culture, suggesting that the CD34+ cells were able to differentiate into a range of blood cell types. Morphological examination showed that MS-5 stromal cells grew on the surface of the particles and bridged the gaps between them to form a 3D structure. Hematopoietic cells slipped into the 3D layer and proliferated within it, relying on the presence of the MS-5 cells. These results suggest that this 3D culture system using polymer particles reproduced the hematopoietic phenomenon in vitro, and might thus provide a new tool for investigating hematopoietic stem cell–stromal cell interactions.

Nonspherical chiral helical polymer particles with programmable morphology prepared by electrospraying

Nanoscale ◽  
2019 ◽  
Vol 11 (48) ◽  
pp. 23197-23205 ◽  
Author(s):  
Pengpeng Li ◽  
Kai Pan ◽  
Jianping Deng
Keyword(s):  
Research Field ◽  
Polymer Particles ◽  
Helical Polymer ◽  
New Research

We anticipate that nonspherical chiral particles may open up a new research field as advanced functional micro- and nanomaterials.

SuFExable Polymers with Helical Structures Derived from Thionyl Tetrafluoride (SOF4)

2019 ◽  
Author(s):  
Suhua Li ◽  
Gencheng Li ◽  
Bing Gao ◽  
Sidharam P. Pujari ◽  
Xiaoyan Chen ◽  
...  
Keyword(s):  
Functional Polymers ◽  
Polymer Chains ◽  
New Materials ◽  
Helical Structures ◽  
Polymer Backbone ◽  
Silyl Ethers ◽  
Helical Polymer ◽  
Key Characteristics ◽  
Post Modification ◽  
Individual Polymer

The first SuFEx click chemistry synthesis of SOF<sub>4</sub>-derived copolymers based upon the polymerization of bis(iminosulfur oxydifluorides) and bis(aryl silyl ethers) is described. This novel class of SuFEx polymer presents two key characteristics: First, the newly created [-N=S(=O)F-O-] polymer backbone linkages are themselves SuFExable and primed to undergo further high-yielding and precise SuFEx-based post-modification with phenols or amines to yield branched functional polymers. Second, studies of individual polymer chains of several of these new materials indicate the presence of helical polymer structures, which itself suggests a preferential approach of new monomers onto the growing polymer chain upon the formation of the stereogenic linking moiety.

Synthesis and chiral recognition of optically active hydrogels containing helical polymer chains

2010 ◽  
Vol 1 (7) ◽  
pp. 1030 ◽  
Author(s):  
Xiaoying Du ◽  
Jinbao Liu ◽  
Jianping Deng ◽  
Wantai Yang
Keyword(s):  
Chiral Recognition ◽  
Optically Active ◽  
Polymer Chains ◽  
Helical Polymer

scholarly journals Coordination Behaviour of 1-(4,2′:6′,4′′-terpyridin-4′-yl)ferrocene and 1-(3,2′:6′,3′′-terpyridin-4′-yl)ferrocene: Predictable and Unpredictable Assembly Algorithms

2017 ◽  
Vol 70 (5) ◽  
pp. 468 ◽  
Author(s):  
Y. Maximilian Klein ◽  
Alessandro Prescimone ◽  
Edwin C. Constable ◽  
Catherine E. Housecroft
Keyword(s):  
Crystal Growth ◽  
Polymer Chains ◽  
Stacking Interactions ◽  
Helical Polymer ◽  
Π Stacking ◽  
Coordination Behaviour ◽  
Nitrogen Donors ◽  
Assembly Algorithms ◽  
Growth Experiments

The reaction of 1-(4,2′:6′,4″-terpyridin-4′-yl)ferrocene (2) with ZnI2 leads to [{ZnI2(2)}4·1.4MeOH·0.8H2O] which contains a discrete [4+4] metallocycle. Crystal growth experiments demonstrate that reactions of 2 with Zn(OAc)2 or CuCl2 result in the formation of single- or double-stranded 1D polymer chains, respectively, the latter facilitated by the formation of {Cu2Cl4} dinuclear nodes. While both 2 and its isomer 1-(3,2′:6′,3″-terpyridin-4′-yl)ferrocene (3) present V-shaped donor sets, rotation about interannular bonds in 3 generates flexible vectorial properties associated with limiting convergent and divergent orientations of the nitrogen donors. The synthesis and characterisation of 3 are described as are reactions of 3 with ZnCl2 or ZnBr2 which lead, respectively, to a metallosquare in [{ZnCl2(3)}4·3CHCl3·3MeOH] or a helical polymer in [{ZnBr2(3)}·MeOH]n. The tight pitch of the helix in the latter (8.7879(9) Å) is controlled by a combination of the orientations of the N,N″-donor sets in 3, and intra-chain π-stacking interactions involving ferrocenyl and pyridine units.

Helical Polymer Particles Derived from Aromatic Acetylenics and Prepared by Suspension Polymerization

2015 ◽  
Vol 216 (19) ◽  
pp. 1963-1971 ◽  
Author(s):  
Jiangfeng Lin ◽  
Haiyang Zhang ◽  
Junya Liang ◽  
Jianping Deng
Keyword(s):  
Suspension Polymerization ◽  
Polymer Particles ◽  
Helical Polymer
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