A simple route towards the synthesis of 1,4,5-trisubstituted 1,2,3-triazoles from primary amines and 1,3-dicarbonyl compounds under metal-free conditions

2019 ◽  
Vol 17 (25) ◽  
pp. 6148-6152 ◽  
Author(s):  
Ningxin Guo ◽  
Xiufen Liu ◽  
Hongyan Xu ◽  
Xi Zhou ◽  
Huaiqing Zhao
Keyword(s):  
Primary Amines ◽  
Dicarbonyl Compounds ◽  
Simple Route ◽  
Metal Free ◽  
One Step

A metal-free protocol for the synthesis of fully substituted 1,2,3-triazoles in a one-step reaction from easily available primary amines, 1,3-dicarbonyl compounds and tosyl azide was developed under air.

Ruthenium-catalyzed synthesis of N-substituted lactams by acceptorless dehydrogenative coupling of diols with primary amines

2019 ◽  
Vol 55 (82) ◽  
pp. 12384-12387 ◽  
Author(s):  
Yanling Zheng ◽  
Xufeng Nie ◽  
Yang Long ◽  
Li Ji ◽  
Haiyan Fu ◽  
...  
Keyword(s):  
Phosphine Ligand ◽  
Primary Amines ◽  
Dehydrogenative Coupling ◽  
One Step

The first synthesis of N-substituted lactams via an acceptorless dehydrogenative coupling of diols with primary amines in one step was enabled by combining Ru3(CO)12 with a hybrid N-heterocyclic carbene–phosphine–phosphine ligand as the catalyst.

One-step Synthesis of Amorphous Nickel Iron Phosphide Hierarchical Nanostructures for Water Electrolysis with Superb Stability at High Current Density

2021 ◽  
Author(s):  
Yuefeng Yu ◽  
Xun He ◽  
Rong Li ◽  
Xinglong Gou
Keyword(s):  
High Performance ◽  
High Current Density ◽  
Water Electrolysis ◽  
Bifunctional Catalysts ◽  
High Current ◽  
Hierarchical Nanostructures ◽  
Iron Phosphide ◽  
Nickel Iron ◽  
Metal Free ◽  
One Step

Development of noble-metal-free high-performance bifunctional catalysts for both oxygen evolution reaction (OER) and hydrogen evolution reaction (HER) is essential but challenging for hydrogen production from water electrolysis. Herein, amorphous bimetallic...

scholarly journals Metal-Free Air Oxidation in a Convenient Cascade Approach for the Access to Isoquinoline-1,3,4(2H)-triones

Molecules ◽  
2019 ◽  
Vol 24 (11) ◽  
pp. 2177
Author(s):  
Antonia Di Mola ◽  
Consiglia Tedesco ◽  
Antonio Massa
Keyword(s):  
Heterocyclic Compounds ◽  
Aromatic Ketone ◽  
Primary Amines ◽  
Cascade Process ◽  
Staudinger Reaction ◽  
Caspase Inhibitor ◽  
Air Oxidation ◽  
Metal Free ◽  
Free Air

Herein we describe a very useful application of the readily available trifunctional aromatic ketone methyl-2-(2-bromoacetyl)benzoate in reactions with primary amines. An unexpected in situ air oxidation that follows a cascade process allowed the access to a series of isoquinoline-1,3,4(2H)-triones, a class of heterocyclic compounds of great interest containing an oxygen-rich heterocyclic scaffold. A modification of the original protocol, utilizing a Staudinger reaction in the presence of trimethylphosphine, was necessary for the synthesis of Caspase inhibitor trione with free NH group.

Synthesis of 2-Aryl-5-alkyl-fulleropyrrolidines: Metal-Free-Mediated Reaction of [60]Fullerene with Aromatic Aldehydes and Inactive Primary Amines

2017 ◽  
Vol 82 (16) ◽  
pp. 8617-8627 ◽  
Author(s):  
Meng Zhang ◽  
Hui-Juan Wang ◽  
Fa-Bao Li ◽  
Xin-Xin Zhong ◽  
Yong-Shun Huang ◽  
...  
Keyword(s):  
Aromatic Aldehydes ◽  
Primary Amines ◽  
Metal Free

A general metal-free route towards the synthesis of 1,2,3-triazoles from readily available primary amines and ketones

2016 ◽  
Vol 52 (14) ◽  
pp. 2885-2888 ◽  
Author(s):  
Joice Thomas ◽  
Sampad Jana ◽  
Jubi John ◽  
Sandra Liekens ◽  
Wim Dehaen
Keyword(s):  
Natural Products ◽  
Primary Amines ◽  
Metal Free ◽  
Amino Esters

A metal-free route towards different 1,2,3-triazole heterocycles was accomplished by using inexpensive and readily available ketones and primary amines. This reaction is very general and was extended to functionalize different amino esters, dendrimers and natural products.

Bifunctional metal-free photo-organocatalysts for enantioselective aerobic oxidation of β-dicarbonyl compounds

Tetrahedron ◽  
2018 ◽  
Vol 74 (27) ◽  
pp. 3624-3633 ◽  
Author(s):  
Xiao-fei Tang ◽  
Shi-hao Feng ◽  
Ya-kun Wang ◽  
Fan Yang ◽  
Ze-hao Zheng ◽  
...  
Keyword(s):  
Aerobic Oxidation ◽  
Dicarbonyl Compounds ◽  
Metal Free
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