Selective synthesis of spirooxindoles via a two-step reaction of N-phenacylpyridinium bromide, 1,3-indanedione and N-alkylisations

2019 ◽  
Vol 17 (16) ◽  
pp. 3978-3983 ◽  
Author(s):  
Jing Sun ◽  
Yu Zhang ◽  
Rong-Guo Shi ◽  
Chao-Guo Yan

The three-component reaction resulted in the unique spiro[indoline-3,4′-naphtho[1,2-b]furan] derivatives, which were converted to spiro[indoline-3,2′-naphthalen]-4′-yl acetates by acylation and alkoxy-substituted spiro[benzo[h]chromene-5,3′-indolines] by acid catalyzed etherification.

RSC Advances ◽  
2016 ◽  
Vol 6 (32) ◽  
pp. 26783-26790 ◽  
Author(s):  
Hamid Reza Safaei ◽  
Farbod Dehbozorgi

A rapid and efficient solvent-free one-pot synthesis of novel alkyl amino aryl furan tricarbonitrile derivatives is described under catalyst-free conditions.


2021 ◽  
Vol 57 (76) ◽  
pp. 9708-9711
Author(s):  
Akansha Singh ◽  
Ravindra Kumar

A sustainable catalyst- and solvent-free Passerini-tetrazole three component reaction (PT-3CR) has been developed for the selective synthesis of benzoxaborol-tetrazoles for the first time.


ChemInform ◽  
2013 ◽  
Vol 44 (6) ◽  
pp. no-no
Author(s):  
yuliya V. Filippova ◽  
Anna G. Sukhanova ◽  
Sergei V. Voitekhovich ◽  
Vadim E. Matulis ◽  
Gennady T. Sukhanov ◽  
...  

2019 ◽  
Vol 21 (4) ◽  
pp. 792-797 ◽  
Author(s):  
Jiaoting Pan ◽  
Runmin Zhao ◽  
Jiami Guo ◽  
Dumei Ma ◽  
Ying Xia ◽  
...  

The first facile and efficient acid-catalyzed three-component reaction of indoles, H-phosphine oxides and carbonyl compounds has been developed, providing a general, one-pot approach to structurally diverse C3-alkylated indole derivatives.


2019 ◽  
Vol 15 ◽  
pp. 1061-1064 ◽  
Author(s):  
Alexei Lukin ◽  
Anna Bakholdina ◽  
Anna Kryukova ◽  
Alexander Sapegin ◽  
Mikhail Krasavin

A three-component reaction involving in situ generation of propargylureas and subsequent Zn(OTf)2-mediated cyclocondensation with a primary amine yielded trisubstituted 2-aminoimidazoles. These findings are in contrast to the previously reported base-promoted unimolecular cyclization of propargylureas (leading to 2-imidazolones) and extend the range of Lewis acid-catalyzed azole syntheses based on N-carbonyl propargylamines.


2019 ◽  
Vol 84 (14) ◽  
pp. 9369-9377 ◽  
Author(s):  
Zhengwang Chen ◽  
Pei Liang ◽  
Fan Xu ◽  
Rulin Qiu ◽  
Qi Tan ◽  
...  

2019 ◽  
Vol 21 (11) ◽  
pp. 2938-2945 ◽  
Author(s):  
Durgaiah Chevella ◽  
Arun Kumar Macharla ◽  
Rammurthy Banothu ◽  
Krishna Sai Gajula ◽  
Vasu Amrutham ◽  
...  

A novel heterogeneous acid catalyzed highly selective synthesis of non-symmetrical alkyl carbonates from alcohols and DMC has been developed.


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