Intramolecular hydrogen-bonding-assisted phosphine-catalysed [3 + 2] cyclisation of ynones with o-hydroxy/amino benzaldehydes

2019 ◽  
Vol 17 (8) ◽  
pp. 2187-2191 ◽  
Author(s):  
Zhi-Xiong Deng ◽  
Zhen-Zhen Xie ◽  
Yu Zheng ◽  
Jun-An Xiao ◽  
Rui-Jia Wang ◽  
...  
Keyword(s):  
Hydrogen Bonding ◽  
Aromatic Aldehydes ◽  
Intramolecular Hydrogen Bonding ◽  
Hydroxy Amino ◽  
New Strategy ◽  
Intramolecular Hydrogen

A new strategy for the synthesis of functionalized tetrahydrofuran derivatives was developed via a phosphine-catalysed [3 + 2] annulation reaction of aromatic aldehydes with 4-phenylbut-3-yn-2-one.

scholarly journals Intra-molecular Interactions in Porous Covalent Organic Frameworks

2014 ◽  
Vol 70 (a1) ◽  
pp. C530-C530
Author(s):  
Rahul Banerjee
Keyword(s):  
Hydrogen Bonding ◽  
Schiff Base ◽  
Molecular Interactions ◽  
Chemical Stability ◽  
Intramolecular Hydrogen Bonding ◽  
Covalent Organic Frameworks ◽  
Covalent Organic Framework ◽  
New Strategy ◽  
The Stability ◽  
Intramolecular Hydrogen

A new strategy of intramolecular hydrogen bonding in 2D covalent organic framework as an extra stabilizing factor has been introduced, which helps to improve the crystallinity, porosity and chemical stability of the COF. Using this concept, highly stable porphyrin containing covalent organic frameworks have been synthesized using the Schiff base reaction. The stability of the COFs mainly arises due to the strong intramolecular O-H...N=C hydrogen bonding. Validation of this postulate was cross-checked by synthesizing methoxy (OCH3) substituted COF in which no hyrogen bonding exists. It was found that methoxy substituted COF have a low crystallinity, porosity and chemical stability as compared to hydrogen bonded COF.

scholarly journals The intramolecular hydrogen bonded–halogen bond: a new strategy for preorganization and enhanced binding

2018 ◽  
Vol 9 (26) ◽  
pp. 5828-5836 ◽  
Author(s):  
Asia Marie S. Riel ◽  
Daniel A. Decato ◽  
Jiyu Sun ◽  
Casey J. Massena ◽  
Morly J. Jessop ◽  
...  
Keyword(s):  
Molecular Structure ◽  
Hydrogen Bonding ◽  
Halogen Bond ◽  
Halogen Bonding ◽  
Intramolecular Hydrogen Bonding ◽  
New Strategy ◽  
Intramolecular Hydrogen ◽  
Hydrogen Bonded

Intramolecular hydrogen bonding directly to halogen bond donors preorganizes molecular structure and strengthens halogen bonding.

The emergent intramolecular hydrogen bonding effect on the electronic structures of organic electron acceptors

2017 ◽  
Vol 19 (35) ◽  
pp. 23905-23909 ◽  
Author(s):  
Takashi Takeda ◽  
Yasutaka Suzuki ◽  
Jun Kawamata ◽  
Shin-ichiro Noro ◽  
Takayoshi Nakamura ◽  
...  
Keyword(s):  
Hydrogen Bonding ◽  
Electronic Structures ◽  
Molecular System ◽  
Intramolecular Hydrogen Bonding ◽  
Hydrogen Bonding Interactions ◽  
Bonding Effect ◽  
Organic Electron ◽  
New Strategy ◽  
Intramolecular Hydrogen ◽  
Hydrogen Bonding Effect

A new strategy for controlling the electron-accepting ability of an anthraquinone-based π-molecular system is proposed to take advantage of intramolecular hydrogen bonding interactions.

Theoretical study of intramolecular hydrogen bonding and molecular geometry of 2-trifluoromethylphenol

10.1002/jcc.2 ◽  
1996 ◽  
Vol 17 (16) ◽  
pp. 1804-1819 ◽  
Author(s):  
Attila Kov�cs ◽  
Istv�n Kolossv�ry ◽  
G�bor I. Csonka ◽  
Istv�n Hargittai
Keyword(s):  
Hydrogen Bonding ◽  
Theoretical Study ◽  
Molecular Geometry ◽  
Intramolecular Hydrogen Bonding ◽  
Intramolecular Hydrogen

Intramolecular Hydrogen Bonding Facilitates Electrocatalytic Reduction of Nitrite in Aqueous Solutions

2019 ◽  
Vol 58 (14) ◽  
pp. 9443-9451 ◽  
Author(s):  
Song Xu ◽  
Hyuk-Yong Kwon ◽  
Daniel C. Ashley ◽  
Chun-Hsing Chen ◽  
Elena Jakubikova ◽  
...  
Keyword(s):  
Hydrogen Bonding ◽  
Aqueous Solutions ◽  
Intramolecular Hydrogen Bonding ◽  
Electrocatalytic Reduction ◽  
Intramolecular Hydrogen

Seven-Membered Intramolecular Hydrogen Bonding of Phenols: Database Analysis and Phloroglucinol Model Compounds

2012 ◽  
Vol 2012 (24) ◽  
pp. 4483-4492 ◽  
Author(s):  
Ronald K. Castellano ◽  
Yan Li ◽  
Edwin A. Homan ◽  
Andrew J. Lampkins ◽  
Iris V. Marín ◽  
...  
Keyword(s):  
Hydrogen Bonding ◽  
Intramolecular Hydrogen Bonding ◽  
Model Compounds ◽  
Database Analysis ◽  
Intramolecular Hydrogen

scholarly journals NMR of Natural Products as Potential Drugs

Molecules ◽  
2021 ◽  
Vol 26 (12) ◽  
pp. 3763
Author(s):  
Poul Erik Hansen
Keyword(s):  
Natural Products ◽  
Hydrogen Bonding ◽  
Density Functional ◽  
Chemical Shifts ◽  
Isotope Effects ◽  
Density Functional Theory Calculations ◽  
Intramolecular Hydrogen Bonding ◽  
Chemical Equilibria ◽  
Nmr Techniques ◽  
Intramolecular Hydrogen

This review outlines methods to investigate the structure of natural products with emphasis on intramolecular hydrogen bonding, tautomerism and ionic structures using NMR techniques. The focus is on 1H chemical shifts, isotope effects on chemical shifts and diffusion ordered spectroscopy. In addition, density functional theory calculations are performed to support NMR results. The review demonstrates how hydrogen bonding may lead to specific structures and how chemical equilibria, as well as tautomeric equilibria and ionic structures, can be detected. All these features are important for biological activity and a prerequisite for correct docking experiments and future use as drugs.

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