In situ self-assembled biosupramolecular porphyrin nanofibers for enhancing photodynamic therapy in tumors

Nanoscale ◽  
2020 ◽  
Vol 12 (20) ◽  
pp. 11119-11129 ◽  
Author(s):  
Yang Liu ◽  
Xiaomin Li ◽  
Xiaoyan Niu ◽  
Licheng Yu ◽  
Weizhou Sha ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Hydraulic Pressure ◽  
Forming Strategy ◽  
Self Assembled

Focusing on the high tissue hydraulic pressure in tumors leads to the low retention effect of photosensitizers (PSs), we proposed a “PSs self-fiber forming strategy” to effectively increase PSs concentration in tumor and enhance the PDT effect.

scholarly journals Switching energy dissipation pathway: in situ proton-induced transformation of AIE-active self-assemblies to boost photodynamic therapy

2021 ◽  
Author(s):  
Jie Li ◽  
Jianxing Wang ◽  
Jianyu Zhang ◽  
Xiyao Hu ◽  
Dong Wang ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Energy Dissipation ◽  
Morphological Transformation ◽  
Switching Energy ◽  
Self Assembled

With the morphological transformation of fluorescent self-assembled nanostructures, their functions can be varied simultaneously.

scholarly journals In situ second-harmonic generation mediated photodynamic therapy by micelles co-encapsulating coordination nanoparticle and photosensitizer

RSC Advances ◽  
2017 ◽  
Vol 7 (82) ◽  
pp. 52125-52132 ◽  
Author(s):  
Xuyang Zhou ◽  
Yang Chen ◽  
Jian Su ◽  
Xiaohe Tian ◽  
Yonghuang Luo ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Second Harmonic Generation ◽  
Harmonic Generation ◽  
Nonlinear Optical ◽  
Second Harmonic ◽  
Property A

NIR-PDT strategy was introduced by employing a nonlinear optical conveyor bearing strong second-harmonic generation (SHG) property. A biocompatible micellic system co-delivered the conveyor and photosensitizer for in situ NIR-PDT.

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