Permeation of nanoparticles across the intestinal lipid membrane: dependence on shape and surface chemistry studied through molecular simulations

Nanoscale ◽  
2020 ◽  
Vol 12 (11) ◽  
pp. 6318-6333 ◽  
Author(s):  
Rakesh Gupta ◽  
Yogesh Badhe ◽  
Samir Mitragotri ◽  
Beena Rai
Keyword(s):  
Drug Delivery ◽  
Surface Chemistry ◽  
In Silico ◽  
Lipid Membrane ◽  
Oral Drug Delivery ◽  
Molecular Simulations ◽  
Oral Drug ◽  
Drug Delivery Applications

In-silico design & testing of nanoparticles for oral drug delivery applications.

Preparation and characterization of mucus-penetrating papain/poly(acrylic acid) nanoparticles for oral drug delivery applications

2012 ◽  
Vol 15 (1) ◽  
Author(s):  
Christiane Müller ◽  
Katharina Leithner ◽  
Sabine Hauptstein ◽  
Fabian Hintzen ◽  
Willi Salvenmoser ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Acrylic Acid ◽  
Oral Drug Delivery ◽  
Oral Drug ◽  
Drug Delivery Applications ◽  
Poly Acrylic Acid

scholarly journals Effects of ingested nanocellulose and nanochitosan materials on carbohydrate digestion and absorption in an in vitro small intestinal epithelium model

2021 ◽  
Author(s):  
Zhongyuan Guo ◽  
Glen DeLoid ◽  
Xiaoqiong Cao ◽  
Dimitrios Bitounis ◽  
Kaarunya Sampathkumar ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Intestinal Epithelium ◽  
Oral Drug Delivery ◽  
Oral Drug ◽  
Small Intestinal Epithelium ◽  
Surface Areas ◽  
Small Intestinal ◽  
Drug Delivery Applications ◽  
Carbohydrate Digestion

Nanoscale materials derived from natural biopolymers like cellulose and chitosan have many potentially useful agri-food and oral drug delivery applications. Because of their large and potentially bioactive surface areas and...

Chitosan-based systems for oral drug delivery applications

2022 ◽  
pp. 23-53
Author(s):  
Sabya Sachi Das ◽  
Sweta Kar ◽  
Sandeep Kumar Singh ◽  
P.R.P. Verma ◽  
Afzal Hussain ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Oral Drug Delivery ◽  
Oral Drug ◽  
Drug Delivery Applications

Polyionic complexes of chitosan-N-arginine with alginate as pH responsive and mucoadhesive particles for oral drug delivery applications

2020 ◽  
Vol 148 ◽  
pp. 550-564 ◽  
Author(s):  
Ana C.M. Fernandes Patta ◽  
Patrick D. Mathews ◽  
Rafael R.M. Madrid ◽  
Vera L.S. Rigoni ◽  
Emerson R. Silva ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Oral Drug Delivery ◽  
Oral Drug ◽  
Ph Responsive ◽  
Drug Delivery Applications

scholarly journals Role of nanoparticle size, shape and surface chemistry in oral drug delivery

2016 ◽  
Vol 238 ◽  
pp. 176-185 ◽  
Author(s):  
Amrita Banerjee ◽  
Jianping Qi ◽  
Rohan Gogoi ◽  
Jessica Wong ◽  
Samir Mitragotri
Keyword(s):  
Drug Delivery ◽  
Surface Chemistry ◽  
Oral Drug Delivery ◽  
Nanoparticle Size ◽  
Oral Drug

scholarly journals Polymer–Enzyme Conjugates for Oral Drug Delivery Applications

2013 ◽  
Vol 67 (9) ◽  
pp. 685-685 ◽  
Author(s):  
Gregor Fuhrmann ◽  
Marc A. Gauthier ◽  
Jean-Christophe Leroux
Keyword(s):  
Drug Delivery ◽  
Oral Drug Delivery ◽  
Oral Drug ◽  
Drug Delivery Applications

Applications of Ion Exchange Resin in Oral Drug Delivery Systems

2017 ◽  
Vol 7 (03) ◽  
Author(s):  
Kathpalia Harsha ◽  
Das Sukanya
Keyword(s):  
Drug Delivery ◽  
Ion Exchange ◽  
Drug Delivery Systems ◽  
Oral Drug Delivery ◽  
Physical Stability ◽  
Delivery Systems ◽  
Oral Drug ◽  
Ion Exchange Resins ◽  
Exchange Resins ◽  
Oral Drug Delivery Systems

Ion Exchange Resins (IER) are insoluble polymers having styrene divinylbenzene copolymer backbone that contain acidic or basic functional groups and have the ability to exchange counter ions with the surrounding aqueous solutions. From the past many years they have been widely used for purification and softening of water and in chromatographic columns, however recently their use in pharmaceutical industry has gained considerable importance. Due to the physical stability and inert nature of the resins, they can be used as a versatile vehicle to design several modified release dosage forms The ionizable drug is complexed with the resin owing to the property of ion exchange. This resin complex dissociatesin vivo to release the drug. Based on the dissociation strength of the drug from the drug resin complex, various release patterns can be achieved. Many formulation glitches can be circumvented using ion exchange resins such as bitter taste and deliquescence. These resins also aid in enhancing disintegrationand stability of formulation. This review focuses on different types of ion exchange resins, their preparation methods, chemistry, properties, incompatibilities and their application in various oral drug delivery systems as well as highlighting their use as therapeutic agents.

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