Label-free and enzyme-free detection of microRNA based on a hybridization chain reaction with hemin/G-quadruplex enzymatic catalysis-induced MoS2 quantum dots via the inner filter effect

Nanoscale ◽  
2020 ◽  
Vol 12 (2) ◽  
pp. 808-814 ◽  
Author(s):  
Jia Ge ◽  
Zhangyu Qi ◽  
Liangliang Zhang ◽  
Xueping Shen ◽  
Yanmei Shen ◽  
...  

A new label-free, enzyme-free, and specific strategy for the assay of microRNA has been developed based on a hybridization chain reaction with hemin/G-quadruplex enzymatic catalysis-induced MoS2 quantum dots via the inner filter effect.

Talanta ◽  
2015 ◽  
Vol 138 ◽  
pp. 15-19 ◽  
Author(s):  
Qingai Chen ◽  
Qingquan Guo ◽  
Ying Chen ◽  
Jie Pang ◽  
Fengfu Fu ◽  
...  

The Analyst ◽  
2015 ◽  
Vol 140 (17) ◽  
pp. 6124-6130 ◽  
Author(s):  
Zhilu Shi ◽  
Xiafei Zhang ◽  
Rui Cheng ◽  
Baoxin Li ◽  
Yan Jin

A label-free and enzyme-free amplification strategy has been developed for sensitively and specifically studying PNK activity and inhibitionviathe hybridization chain reaction (HCR).


2020 ◽  
Vol 56 (12) ◽  
pp. 1811-1814 ◽  
Author(s):  
Xin Song ◽  
Ting Hou ◽  
Fangfang Lu ◽  
Yuze Wang ◽  
Junjie Liu ◽  
...  

We develop a label-free homogeneous photoelectrochemical biosensing strategy for microRNA quantification based on the synergy of G-quadruplex/hemin catalyzed electron donor consumption and the inner filter effect.


2021 ◽  
Author(s):  
Qianqian Zhao ◽  
Datong Wu ◽  
Zhengzhi Yin ◽  
Wenrong Cai ◽  
Haifeng Zhou ◽  
...  

A fluorescent chiral sensor is proposed based on the inner filter effect (IFE) of chiral Au nanoparticles (AuNPs) on MoS2 quantum dots (MoS2 QDs), which can be used for the...


RSC Advances ◽  
2016 ◽  
Vol 6 (62) ◽  
pp. 57502-57506 ◽  
Author(s):  
Lin Liu ◽  
Qing Li ◽  
Li-Juan Tang ◽  
Ru-Qin Yu ◽  
Jian-Hui Jiang

A hybridization chain reaction (HCR) lightened by DNA-stabilized silver nanoclusters (AgNCs) as a label-free and turn on fluorescence platform for nucleic acid assays.


RSC Advances ◽  
2015 ◽  
Vol 5 (55) ◽  
pp. 44714-44721 ◽  
Author(s):  
Siqi Zhang ◽  
Kun Wang ◽  
Zhenyu Li ◽  
Zhongmin Feng ◽  
Ting Sun

Upon adding THBV, the self-assembly of THBV with H1 allows the rest of the DNA sequence of H1 to accelerate H1–H2 complex formation. The G-quadruplex at the end of the H1–H2 complex could catalyze TMB into a colored product.


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