Photo-crosslinkable elastomeric protein-derived supramolecular peptide hydrogel with controlled therapeutic CO-release

Nanoscale ◽  
2019 ◽  
Vol 11 (37) ◽  
pp. 17327-17333 ◽  
Author(s):  
Inhye Kim ◽  
Woo-Young Bang ◽  
Won Ho Park ◽  
Eun Hee Han ◽  
Eunji Lee
Keyword(s):  
Visible Light ◽  
Mechanical Strength ◽  
Short Peptides ◽  
Peptide Hydrogel

Visible light-mediated crosslinkable CO-releasing peptide hydrogel with enhanced mechanical strength and stability was developed by fibrillar assembly of elastomeric protein-derived short peptides.

scholarly journals Improving gelation efficiency and cytocompatibility of visible light polymerized thiol-norbornene hydrogels via addition of soluble tyrosine

2017 ◽  
Vol 5 (3) ◽  
pp. 589-599 ◽  
Author(s):  
Han Shih ◽  
Hung-Yi Liu ◽  
Chien-Chi Lin
Keyword(s):  
Visible Light ◽  
Peptide Hydrogel

A biomimetic PEG-peptide hydrogel was developed through tyrosine-assisted visible-light thiol-norbornene crosslinking. Soluble tyrosine improves crosslinking and enhances the cytocompatibility of hydrogels.

scholarly journals Systematic exploration of the pH dependence of a peptide hydrogel

2019 ◽  
Vol 97 (6) ◽  
pp. 430-434 ◽  
Author(s):  
Natashya Falcone ◽  
Tsuimy Shao ◽  
Xiaoyi Sun ◽  
Heinz-Bernhard Kraatz
Keyword(s):  
Mechanical Strength ◽  
Narrow Range ◽  
Ph Dependence ◽  
Stimuli Responsive ◽  
Systematic Exploration ◽  
Ph Conditions ◽  
Ph Dependent ◽  
Functional Biomaterials ◽  
Peptide Hydrogel

Stimuli-responsive peptide gels are a growing class of functional biomaterials that are involved in many applications in research. Here, we present a novel di-peptide hydrogel from the compound Boc–Phe–Trp–OH in various buffer and pH conditions. We examine the effects of different stimuli, including temperature and pH, on the mechanical strength of the gels through frequency rheology studies. We found that this hydrogelator is highly pH dependent, only forming a gel in a narrow range of pH 6–7. This hydrogelator hold promise for the development of new stimuli-responsive biomaterials for specific applications that require this type of specific stimuli.

Mechanical strength of urethane-based visible-light-cured resins

1993 ◽  
Vol 4 (4) ◽  
pp. 404-406 ◽  
Author(s):  
K. Wakasa ◽  
H. Urabe ◽  
M. Taira ◽  
T. Hirose ◽  
M. Yamaki
Keyword(s):  
Visible Light ◽  
Mechanical Strength

scholarly journals Experimental study of the LED lamp

2021 ◽  
Vol 338 ◽  
pp. 01015
Author(s):  
Marek Markowicz ◽  
Emil Smyk ◽  
Robert Smusz
Keyword(s):  
Experimental Study ◽  
Power Consumption ◽  
Low Power ◽  
Visible Light ◽  
Mechanical Strength ◽  
Radiant Energy ◽  
Electrical Energy ◽  
Low Power Consumption ◽  
Light Sources ◽  
Basic Parameters

LEDs are widely used light sources. Their main advantages are low power consumption, mechanical strength, high luminous efficacy, and a lifetime exceeding 50 000 hours. However, compared to other light sources, they are more sensitive to high temperatures. Heat is generated by converting electrical energy into radiant energy. The share of heat in this transformation describes the efficiency, but in the case of light sources, efficiency is not one of the basic parameters because only a part of the radiation produced is visible light, which interests the recipients. However, the temperature has a big influence on the properties and lifetime of LEDs. This article presents the results of temperature measurements of the LED lamp.

Studies of metaphase chromosomes in the scanning transmission x-ray microscope: Image fidelity, radiation damage and specimen preparation

1992 ◽  
Vol 50 (2) ◽  
pp. 1038-1039
Author(s):  
Shawn Williams ◽  
Xiaodong Zhang ◽  
Susan Lamm ◽  
Jack Van’t Hof
Keyword(s):  
Visible Light ◽  
Radiation Damage ◽  
Cross Section ◽  
Imaging Techniques ◽  
Dose Range ◽  
Specimen Preparation ◽  
X Rays ◽  
Metaphase Chromosomes ◽  
X Ray ◽  
Scanning Transmission

The Scanning Transmission X-ray Microscope (STXM) is well suited for investigating metaphase chromosome structure. The absorption cross-section of soft x-rays having energies between the carbon and oxygen K edges (284 - 531 eV) is 6 - 9.5 times greater for organic specimens than for water, which permits one to examine unstained, wet biological specimens with resolution superior to that attainable using visible light. The attenuation length of the x-rays is suitable for imaging micron thick specimens without sectioning. This large difference in cross-section yields good specimen contrast, so that fewer soft x-rays than electrons are required to image wet biological specimens at a given resolution. But most imaging techniques delivering better resolution than visible light produce radiation damage. Soft x-rays are known to be very effective in damaging biological specimens. The STXM is constructed to minimize specimen dose, but it is important to measure the actual damage induced as a function of dose in order to determine the dose range within which radiation damage does not compromise image quality.

Scanning luminescence x-ray microscopy: Progress toward selective staining using microspheres

1994 ◽  
Vol 52 ◽  
pp. 74-75
Author(s):  
C. Jacobsen ◽  
J. Fu ◽  
S. Mayer ◽  
Y. Wang ◽  
S. Williams
Keyword(s):  
Visible Light ◽  
Active Sites ◽  
Light Emission ◽  
Chinese Hamster ◽  
Polystyrene Spheres ◽  
Good Resistance ◽  
X Ray ◽  
Selective Staining ◽  
Visible Light Emission ◽  
Specific Labelling

In scanning luminescence x-ray microscopy (SLXM), a high resolution x-ray probe is used to excite visible light emission (see Figs. 1 and 2). The technique has been developed with a goal of localizing dye-tagged biochemically active sites and structures at 50 nm resolution in thick, hydrated biological specimens. Following our initial efforts, Moronne et al. have begun to develop probes based on biotinylated terbium; we report here our progress towards using microspheres for tagging.Our initial experiments with microspheres were based on commercially-available carboxyl latex spheres which emitted ~ 5 visible light photons per x-ray absorbed, and which showed good resistance to bleaching under x-ray irradiation. Other work (such as that by Guo et al.) has shown that such spheres can be used for a variety of specific labelling applications. Our first efforts have been aimed at labelling ƒ actin in Chinese hamster ovarian (CHO) cells. By using a detergent/fixative protocol to load spheres into cells with permeabilized membranes and preserved morphology, we have succeeded in using commercial dye-loaded, spreptavidin-coated 0.03μm polystyrene spheres linked to biotin phalloidon to label f actin (see Fig. 3).

Photocatalyst-free decarboxylative aminoalkylation of imidazo[1,2-a]pyridines with N-aryl glycines enabled by visible light

2019 ◽  
Vol 6 (21) ◽  
pp. 3693-3697 ◽  
Author(s):  
Jiu-Jian Ji ◽  
Zhi-Qiang Zhu ◽  
Li-Jin Xiao ◽  
Dong Guo ◽  
Xiao Zhu ◽  
...  
Keyword(s):  
Visible Light

A novel, green and efficient visible-light-promoted decarboxylative aminoalkylation reaction of imidazo[1,2-a]pyridines with N-aryl glycines has been described.

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