Nanomechanical sub-surface mapping of living biological cells by force microscopy

Nanoscale ◽  
2019 ◽  
Vol 11 (27) ◽  
pp. 13089-13097 ◽  
Author(s):  
Lukas Stühn ◽  
Anna Fritschen ◽  
Joseph Choy ◽  
Martin Dehnert ◽  
Christian Dietz

Atomic force microscopy allows for the acquisition of depth-resolved nanomechanical properties deduced from maps of force–distance curves recorded on cancerous epithelial breast cells.

2012 ◽  
Vol 45 (27) ◽  
pp. 275301 ◽  
Author(s):  
Hyunsoo Lee ◽  
Weonho Shin ◽  
Jang Wook Choi ◽  
Jeong Young Park

2020 ◽  
Vol 570 ◽  
pp. 362-374 ◽  
Author(s):  
Nan Yang ◽  
Chunxia Su ◽  
Yuemei Zhang ◽  
Junji Jia ◽  
Robert L. Leheny ◽  
...  

RSC Advances ◽  
2019 ◽  
Vol 9 (47) ◽  
pp. 27464-27474 ◽  
Author(s):  
Xinfeng Tan ◽  
Dan Guo ◽  
Jianbin Luo

Dynamic force microscopy (DFM) has become a multifunctional and powerful technique for the study of the micro–nanoscale imaging and force detection, especially in the compositional and nanomechanical properties of polymers.


2005 ◽  
Vol 187 (11) ◽  
pp. 3864-3868 ◽  
Author(s):  
Fabien Gaboriaud ◽  
Sidney Bailet ◽  
Etienne Dague ◽  
Frédéric Jorand

ABSTRACT The nanomechanical properties of gram-negative bacteria (Shewanella putrefaciens) were investigated in situ in aqueous solutions at two pH values, specifically, 4 and 10, by atomic force microscopy (AFM). For both pH values, the approach force curves exhibited subsequent nonlinear and linear regimens that were related to the progressive indentation of the AFM tip in the bacterial cell wall, including a priori polymeric fringe (nonlinear part), while the linear part was ascribed to compression of the plasma membrane. These results indicate the dynamic of surface ultrastructure in response to changes in pH, leading to variations in nanomechanical properties, such as the Young's modulus and the bacterial spring constant.


2010 ◽  
Vol 79 (1) ◽  
pp. 284-290 ◽  
Author(s):  
Judith Arfsten ◽  
Stefan Leupold ◽  
Christian Bradtmöller ◽  
Ingo Kampen ◽  
Arno Kwade

Sign in / Sign up

Export Citation Format

Share Document