Advancing neodymium single-band nanothermometry

Nanoscale ◽  
2019 ◽  
Vol 11 (23) ◽  
pp. 11322-11330 ◽  
Author(s):  
A. Skripka ◽  
A. Morinvil ◽  
M. Matulionyte ◽  
T. Cheng ◽  
F. Vetrone
Keyword(s):  
Single Band ◽  
Temperature Sensing ◽  
Stark Structure ◽  
Imaging Probes

Nd3+ doped LiLuF4 nanoparticles are explored as photoluminescent nanothermometers and imaging probes. Such host-dopant configuration permits to resolve the fine Stark structure of Nd3+ photoluminescence at 1050 nm, and to use it for subcutaneous temperature sensing.

Optical imaging probes and their potential contribution to radiotracer development

2016 ◽  
Vol 55 (02) ◽  
pp. 51-62 ◽  
Author(s):  
S. Hermann ◽  
M. Schäfers ◽  
C. Höltke ◽  
A. Faust
Keyword(s):  
Optical Imaging ◽  
Fluorescent Dyes ◽  
Great Influence ◽  
Potential Contribution ◽  
Preclinical Evaluation ◽  
Guided Surgery ◽  
Fluorescence Guided Surgery ◽  
Imaging Probes ◽  
Unspecific Binding

SummaryOptical imaging has long been considered a method for histological or microscopic investigations. Over the last 15 years, however, this method was applied for preclinical molecular imaging and, just recently, was also able to show its principal potential for clinical applications (e.g. fluorescence-guided surgery). Reviewing the development and preclinical evaluation of new fluorescent dyes and target-specific dye conjugates, these often show characteristic patterns of their routes of excretion and biodistribution, which could also be interesting for the development and optimization of radiopharmaceuticals. Especially ionic charges show a great influence on biodistribution and netcharge and charge-distribution on a conjugate often determines unspecific binding or background signals in liver, kidney or intestine, and other organs.Learning from fluorescent probe behaviour in vivo and translating this knowledge to radio-pharmaceuticals might be useful to further optimize emerging and existing radiopharmaceuticals with respect to their biodistribution and thereby availability for binding to their targets.

A New Scanning Thermal Microprobe

1997 ◽  
Vol 503 ◽  
Author(s):  
Yongxia Zhang ◽  
Yanwei Zhang ◽  
Juliana Blaser ◽  
T. S. Sriiram ◽  
R. B. Marcus
Keyword(s):  
Thin Film ◽  
High Resolution ◽  
Thermal Response ◽  
Temperature Sensing ◽  
Thermal Sensor ◽  
Atomic Force ◽  
Thin Film Thermocouple ◽  
Processing Steps ◽  
Thermocouple Junction

ABSTRACTA thermal microprobe has been designed and built for high resolution temperature sensing. The thermal sensor is a thin-film thermocouple junction at the tip of an Atomic Force Microprobe (AFM) silicon probe needle. Only wafer-stage processing steps are used for the fabrication. The thermal response over the range 25–s 4.5–rovolts per degree C and is linear.

A Single Band Antenna Design for Future Millimeter Wave Wireless Communication at 38 GHz

2018 ◽  
Vol 3 (1) ◽  
pp. 35 ◽  
Author(s):  
Cihat Şeker ◽  
Turgut Ozturk ◽  
Muhammet Tahir Güneşer
Keyword(s):  
Millimeter Wave ◽  
Mobile Communications ◽  
Return Loss ◽  
Computer Software ◽  
Dielectric Substrate ◽  
Single Band ◽  
Microstrip Patch ◽  
Fifth Generation ◽  
Wireless Application ◽  
5G Mobile Communications

In this proposed paper, a single band microstrip patch antenna for fifth generation (5G) wireless application was presented. 28, 38, 60 and 73 GHz frequency bands have been allocated for 5G mobile communications by International Telecommunications Union (ITU). In this paper, we proposed an antenna, which is suitable for the millimeter wave frequency. The single band antenna consists of new slot loaded on the radiating patch with the 50 ohms microstrip line feeding used. This single band antenna was simulated on a FR4 dielectric substrate have relative permittivity 4.4, loss tangent 0.02, and height 1.6 mm. The antenna was simulated by Electromagnetic simulation, computer software technology High Frequency Structural Simulator. And simulated result on return loss, VSWR, radiation pattern and 3D gain was presented. The parameters of the results well coherent and proved the literature for millimeter wave 5G wireless application at 38 GHz.

Radiolabeled Imaging Probes Targeting Angiogenesis for Personalized Medicine

2014 ◽  
Vol 20 (14) ◽  
pp. 2293-2307 ◽  
Author(s):  
Samantha Terry ◽  
Mark Rijpkema ◽  
Keelara Abiraj ◽  
Winette Graaf ◽  
Wim Oyen ◽  
...  
Keyword(s):  
Personalized Medicine ◽  
Imaging Probes

PET Imaging of Adenosine Receptors in Diseases

2019 ◽  
Vol 19 (16) ◽  
pp. 1445-1463 ◽  
Author(s):  
Jindian Li ◽  
Xingfang Hong ◽  
Guoquan Li ◽  
Peter S. Conti ◽  
Xianzhong Zhang ◽  
...  
Keyword(s):  
Pet Imaging ◽  
Adenosine Receptors ◽  
Neurological Diseases ◽  
G Protein Coupled Receptors ◽  
Extracellular Adenosine ◽  
Positron Emission ◽  
Imaging Probes ◽  
Pet Probes ◽  
Cancer And Inflammation ◽  
G Protein Coupled

Adenosine receptors (ARs) are a class of purinergic G-protein-coupled receptors (GPCRs). Extracellular adenosine is a pivotal regulation molecule that adjusts physiological function through the interaction with four ARs: A1R, A2AR, A2BR, and A3R. Alterations of ARs function and expression have been studied in neurological diseases (epilepsy, Alzheimer’s disease, and Parkinson’s disease), cardiovascular diseases, cancer, and inflammation and autoimmune diseases. A series of Positron Emission Tomography (PET) probes for imaging ARs have been developed. The PET imaging probes have provided valuable information for diagnosis and therapy of diseases related to alterations of ARs expression. This review presents a concise overview of various ARs-targeted radioligands for PET imaging in diseases. The most recent advances in PET imaging studies by using ARs-targeted probes are briefly summarized.

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