Ni–Fe hybrid nanocubes: an efficient electrocatalyst for non-enzymatic glucose sensing with a wide detection range

2019 ◽  
Vol 43 (28) ◽  
pp. 11135-11140 ◽  
Author(s):  
Cancan Bao ◽  
Qiangqiang Niu ◽  
Xiaowei Cao ◽  
Chang Liu ◽  
Hui Wang ◽  
...  
Keyword(s):  
Glucose Sensing ◽  
Detection Range ◽  
Sensing Performance

A sensor for the determination of glucose is developed based on Ni–Fe hybrid nanocubes, which exhibit excellent sensing performance.

scholarly journals Ratiometric Fluorescent Biosensors for Glucose and Lactate Using an Oxygen-Sensing Membrane

Biosensors ◽  
2021 ◽  
Vol 11 (7) ◽  
pp. 208
Author(s):  
Hong Dinh Duong ◽  
Jong Il Rhee
Keyword(s):  
Limit Of Detection ◽  
Oxygen Sensing ◽  
High Sensitivity ◽  
Glucose Sensing ◽  
Oxidation Reactions ◽  
Lactate Oxidase ◽  
Lactate Oxidation ◽  
Detection Range ◽  
Quenching Effect ◽  
Sensing Membrane

In this study, ratiometric fluorescent glucose and lactate biosensors were developed using a ratiometric fluorescent oxygen-sensing membrane immobilized with glucose oxidase (GOD) or lactate oxidase (LOX). Herein, the ratiometric fluorescent oxygen-sensing membrane was fabricated with the ratio of two emission wavelengths of platinum meso-tetra (pentafluorophenyl) porphyrin (PtP) doped in polystyrene particles and coumarin 6 (C6) captured into silica particles. The operation mechanism of the sensing membranes was based on (i) the fluorescence quenching effect of the PtP dye by oxygen molecules, and (ii) the consumption of oxygen levels in the glucose or lactate oxidation reactions under the catalysis of GOD or LOX. The ratiometric fluorescent glucose-sensing membrane showed high sensitivity to glucose in the range of 0.1–2 mM, with a limit of detection (LOD) of 0.031 mM, whereas the ratiometric fluorescent lactate-sensing membrane showed the linear detection range of 0.1–0.8 mM, with an LOD of 0.06 mM. These sensing membranes also showed good selectivity, fast reversibility, and stability over long-term use. They were applied to detect glucose and lactate in artificial human serum, and they provided reliable measurement results.

Ultrasensitive determination of chloramphenicol in pork and chicken meat samples using a portable electrochemical sensor: effects of 2D nanomaterials on the sensing performance and stability

2021 ◽  
Author(s):  
Ngo Xuan Dinh ◽  
Tuyet Nhung Pham ◽  
Tran Quang Huy ◽  
Do Quang Trung ◽  
Pham Anh Tuan ◽  
...  
Keyword(s):  
Electrochemical Sensor ◽  
Food Samples ◽  
Chicken Meat ◽  
Electrochemical Sensing ◽  
Portable Sensors ◽  
2D Nanomaterials ◽  
Meat Samples ◽  
Sensing Performance

This work contributes to a deeper understanding of the effects of functional 2D nanomaterials on the electrochemical sensing performance of SPE-based portable sensors for the rapid, accurate, and on-site determination of CAP in food samples.

scholarly journals Portable smartphone-integrated paper sensors for fluorescence detection of As(III) in groundwater

2020 ◽  
Vol 7 (12) ◽  
pp. 201500
Author(s):  
Sha Liu ◽  
Yong Li ◽  
Chao Yang ◽  
Liqiang Lu ◽  
Yulun Nie ◽  
...  
Keyword(s):  
Environmental Problem ◽  
Visual Detection ◽  
High Sensitivity ◽  
Integration System ◽  
Detection Range ◽  
Sensitivity And Selectivity ◽  
Toxic Metalloid ◽  
Interfering Ions ◽  
Cu Nanoclusters

Arsenic contamination in groundwater is a supreme environmental problem, and levels of this toxic metalloid must be strictly monitored by a portable, sensitive and selective analytical device. Herein, a new system of smartphone-integrated paper sensors with Cu nanoclusters was established for the effective detection of As(III) in groundwater. For the integration system, the fluorescence emissive peak of Cu nanoclusters at 600 nm decreased gradually with increasing As(III) addition. Meanwhile, the fluorescence colour also changed from orange to colourless, and the detection limit was determined as 2.93 nM (0.22 ppb) in a wide detection range. The interfering ions also cannot influence the detection selectivity of As(III). Furthermore, the portable paper sensors based on Cu nanoclusters were fabricated for visual detection of As(III) in groundwater. The quantitative determination of As(III) in natural groundwater has also been accomplished with the aid of a common smartphone. Our work has provided a portable and on-site detection technique toward As(III) in groundwater with high sensitivity and selectivity.

scholarly journals Single-Step Formation of Ni Nanoparticle-Modified Graphene–Diamond Hybrid Electrodes for Electrochemical Glucose Detection

Sensors ◽  
2019 ◽  
Vol 19 (13) ◽  
pp. 2979 ◽  
Author(s):  
Naiyuan Cui ◽  
Pei Guo ◽  
Qilong Yuan ◽  
Chen Ye ◽  
Mingyang Yang ◽  
...  
Keyword(s):  
Glucose Sensing ◽  
Single Step ◽  
Diamond Surface ◽  
Glucose Detection ◽  
Ni Nanoparticles ◽  
Step Method ◽  
Detection Range ◽  
Graphene Layers ◽  
Potential Applications ◽  
Modified Graphene

The development of accurate, reliable devices for glucose detection has drawn much attention from the scientific community over the past few years. Here, we report a single-step method to fabricate Ni nanoparticle-modified graphene–diamond hybrid electrodes via a catalytic thermal treatment, by which the graphene layers are directly grown on the diamond surface using Ni thin film as a catalyst, meanwhile, Ni nanoparticles are formed in situ on the graphene surface due to dewetting behavior. The good interface between the Ni nanoparticles and the graphene guarantees efficient charge transfer during electrochemical detection. The fabricated electrodes exhibit good glucose sensing performance with a low detection limit of 2 μM and a linear detection range between 2 μM–1 mM. In addition, this sensor shows great selectivity, suggesting potential applications for sensitive and accurate monitoring of glucose in human blood.

Liquid Chromatographic Method for Quantitative Determination of Free Fatty Acids in Butter

1984 ◽  
Vol 67 (4) ◽  
pp. 718-721 ◽  
Author(s):  
Alan W Reed ◽  
Hilton C Deeth ◽  
Donald E Clegg
Keyword(s):  
Fatty Acids ◽  
Free Fatty Acids ◽  
Chromatographic Method ◽  
Water System ◽  
Internal Standard ◽  
Detection Range ◽  
Water Solvent ◽  
Liquid Chromatographic Method ◽  
Liquid Chromatographic

Abstract A liquid chromatographic method has been developed for the determination of free fatty acids in butter. The fatty acids are converted to the p-bromophenacyl esters, via a crown ether-catalyzed reaction, without separation from the other butter components. The esters are separated on a Cis-bonded silica column by using an acetonitrile-water solvent gradient and quantitated using the ester of heptadecanoic acid as internal standard. Cu, and C ,S:i co-elute in the acetonitrile-water system but are separated using an isocratic methanol-acetonitrile-water system. Limits of detection range from 7 ng for butyric acid to 45 ng for linoleic acid. The average coefficient of variation (n = 10) for 10 free fatty acids from,a butter was 5.83%.

scholarly journals Pharmacokinetics and Bioavailability Study of Monocrotaline in Mouse Blood by Ultra-Performance Liquid Chromatography-Tandem Mass Spectrometry

2018 ◽  
Vol 2018 ◽  
pp. 1-10 ◽  
Author(s):  
Lianguo Chen ◽  
Bin Zhang ◽  
Jinlai Liu ◽  
Zhehua Fan ◽  
Ziwei Weng ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Liquid Chromatography ◽  
Tandem Mass Spectrometry ◽  
Quantitative Determination ◽  
Ultra Performance Liquid Chromatography ◽  
New Method ◽  
Tandem Mass ◽  
Mouse Blood ◽  
Detection Range

Background and Aims. The present study aimed to develop a simple and sensitive method for quantitative determination of monocrotaline (MCT) in mouse blood employing ultra-performance liquid chromatography-electrospray ionization tandem mass spectrometry (UPLC-ESI/MS/MS) using rhynchophylline as an internal standard. Methods. Proteins present in the blood samples were precipitated using acetonitrile. MCT was separated using a 1.7-μm ethylene bridged hybrid (BEH) C18 column (2.1 mm × 50 mm) with a gradient elution program and a constant flow rate of 0.4 mL/min. The LC mobile phase consisted of 10 mmol/L ammonium acetate (containing 0.1% formic acid) and acetonitrile. The total elution time was 4.0 min. The analytes were detected on a UPLC-ESI mass spectrometer in multiple reaction monitoring (MRM) mode and quantified. Results. The new method for the determination of MCT has a satisfactory linear detection range of 1-2000 ng/mL and excellent linearity (r = 0.9971). The lower limit of quantification (LLOQ) of MCT is 1.0 ng/mL. Intra- and interassay precisions of MCT were ≤13% with an accuracy from 96.2% to 106.6%. The average recovery of the new method was >75.0%, and matrix effects were between 89.0% and 94.3%. Based on the pharmacokinetics data, the bioavailability of MCT in mice was 88.3% after oral administration. Conclusions. The results suggest that the newly standardized method for quantitative determination of MCT in whole blood is fast, reliable, specific, sensitive, and suitable for pharmacokinetic studies of MCT after intravenous or intragastric administration.

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