scholarly journals Thermodynamic and spectroscopic study of Cu(ii) and Zn(ii) complexes with the (148–156) peptide fragment of C4YJH2, a putative metal transporter of Candida albicans

Metallomics ◽  
2019 ◽  
Vol 11 (12) ◽  
pp. 1988-1998 ◽  
Author(s):  
Denise Bellotti ◽  
Cinzia Tocchio ◽  
Remo Guerrini ◽  
Magdalena Rowińska-Żyrek ◽  
Maurizio Remelli
Keyword(s):  
Candida Albicans ◽  
Spectroscopic Study ◽  
Peptide Fragment ◽  
Linker Sequence ◽  
Metal Transporter ◽  
Coordination Sites

The linker sequence between the two main Cu(ii) and Zn(ii) coordination sites of C4YJH2, a putative metal transporter of Candida albicans, contributes in a non-negligible way to the protein chelating capability.

scholarly journals Spectroscopic Study of the Molecular Structure of the New Hybrid with a Potential Two-Way Antibacterial Effect

Molecules ◽  
2021 ◽  
Vol 26 (5) ◽  
pp. 1442
Author(s):  
Dorota Kowalczuk ◽  
Agata Gładysz ◽  
Monika Pitucha ◽  
Daniel M. Kamiński ◽  
Agnieszka Barańska ◽  
...  
Keyword(s):  
Spectroscopic Study ◽  
Good Alternative ◽  
Structure Characterization ◽  
Resonance Spectroscopy ◽  
Spectroscopic Techniques ◽  
Bacterial Strains ◽  
Active Components ◽  
Hybrid Compound ◽  
Coordination Sites ◽  
Almost All

Bacterial strains become resistant to almost all classes of antibiotics, which makes it necessary to look for new substitutes. The non-absorbable ciprofloxacin–biguanide bismuth complex, used locally, may be a good alternative to a conventional therapy. The purpose of this study was to study the structure of the proposed ciprofloxacin (CIP) -bismuth(III)—chlorhexidine (CHX) composite (CIP-Bi-CHX). The spectroscopic techniques such as UV-VIS (ultraviolet-visible) spectroscopy, FTIR (Fourier-transform infrared) spectroscopy and NMR (Nuclear Magnetic Resonance) spectroscopy were used for structure characterization of the hybrid compound. The performed analysis confirmed the presence of the two active components—CIP and CHX and revealed the possible coordination sites of the ligands with bismuth ion in the metallo-organic structure. Spectroscopic study showed that the complexation between Bi(III) and CIP occurs through the carboxylate and ketone groups of the quinolone ring, while CHX combines with the central ion via the biguanide moieties.

Some Results of the Spectroscopic Study of Four Close Binary Systems of Early Spectral Types

1965 ◽  
Vol 5 ◽  
pp. 120-130
Author(s):  
T. S. Galkina
Keyword(s):  
Spectroscopic Study ◽  
Spectral Type ◽  
Spectroscopic Investigation ◽  
Binary Systems ◽  
Quantitative Information ◽  
Close Binary ◽  
Physical Parameters ◽  
Absorption And Emission ◽  
Close Binary Systems ◽  
Quantitative Estimates

It is necessary to have quantitative estimates of the intensity of lines (both absorption and emission) to obtain the physical parameters of the atmosphere of components.Some years ago at the Crimean observatory we began the spectroscopic investigation of close binary systems of the early spectral type with components WR, Of, O, B to try and obtain more quantitative information from the study of the spectra of the components.

Effect of pH and inhibitors on beta-amyloid fibril assembly

1996 ◽  
Vol 54 ◽  
pp. 752-753
Author(s):  
Beverly E. Maleeff ◽  
Timothy K. Hart ◽  
Stephen J. Wood ◽  
Ronald Wetzel
Keyword(s):  
Amyloid Fibril ◽  
Peptide Fragment ◽  
Hydrophobic Peptides ◽  
Amyloid Fibril Formation ◽  
Effects Of Ph ◽  
Severity Of The Disease ◽  
Kinetics Of ◽  
The Brain

Alzheimer's disease is characterized post-mortem in part by abnormal extracellular neuritic plaques found in brain tissue. There appears to be a correlation between the severity of Alzheimer's dementia in vivo and the number of plaques found in particular areas of the brain. These plaques are known to be the deposition sites of fibrils of the protein β-amyloid. It is thought that if the assembly of these plaques could be inhibited, the severity of the disease would be decreased. The peptide fragment Aβ, a precursor of the p-amyloid protein, has a 40 amino acid sequence, and has been shown to be toxic to neuronal cells in culture after an aging process of several days. This toxicity corresponds to the kinetics of in vitro amyloid fibril formation. In this study, we report the biochemical and ultrastructural effects of pH and the inhibitory agent hexadecyl-N-methylpiperidinium (HMP) bromide, one of a class of ionic micellar detergents known to be capable of solubilizing hydrophobic peptides, on the in vitro assembly of the peptide fragment Aβ.

Enhanced IgE response to Candida albicans in postoperative invasive candidiasis

1996 ◽  
Vol 26 (4) ◽  
pp. 452-460 ◽  
Author(s):  
J. SAVOLAINEN ◽  
A. RANTALA ◽  
M. NERMES ◽  
L. LEHTONEN ◽  
M. VIANDER
Keyword(s):  
Candida Albicans ◽  
Invasive Candidiasis ◽  
Ige Response

Existence of Candida albicans and microorganisms in denture stomatitis patients

1997 ◽  
Vol 24 (10) ◽  
pp. 788-790 ◽  
Author(s):  
Y. KULAK ◽  
A. ARIKAN ◽  
E. KAZAZOGLU
Keyword(s):  
Candida Albicans ◽  
Denture Stomatitis

A spectroscopic study of soil fulvic acid composition after six-year applications of urban waste compost

Agronomie ◽  
2003 ◽  
Vol 23 (8) ◽  
pp. 719-724 ◽  
Author(s):  
Giovanni Gigliotti ◽  
Alceo Macchioni ◽  
Cristiano Zuccaccia ◽  
Pier Lodovico Giusquiani ◽  
Daniela Businelli
Keyword(s):  
Spectroscopic Study ◽  
Fulvic Acid ◽  
Acid Composition ◽  
Urban Waste
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