Expanding beyond ICP-MS to better understand selenium biochemistry

Metallomics ◽  
2019 ◽  
Vol 11 (12) ◽  
pp. 1974-1983 ◽  
Author(s):  
Barbara R. Cardoso ◽  
Katherine Ganio ◽  
Blaine R. Roberts
Keyword(s):  
Mass Spectrometry ◽  
Inductively Coupled Plasma ◽  
Esi Ms ◽  
Inductively Coupled ◽  
Electrospray Ionisation ◽  
Electrospray Ionisation Mass Spectrometry ◽  
Icp Ms ◽  
Ionisation Mass Spectrometry ◽  
Plasma Mass Spectrometry ◽  
Ionisation Mass

Electrospray ionisation mass spectrometry (ESI-MS) is an alternative to inductively coupled plasma mass spectrometry (ICP-MS) to better understand selenium biochemistry.

Can Laser-Ionisation Time-of-Flight Mass Spectrometry Be a Promising Alternative to Laser Ablation/Inductively-Coupled Plasma Mass Spectrometry and Glow Discharge Mass Spectrometry for the Elemental Analysis of Solids?

2002 ◽  
Vol 8 (3) ◽  
pp. 213-232 ◽  
Author(s):  
Alexander A. Sysoev ◽  
Alexey A. Sysoev
Keyword(s):  
Mass Spectrometry ◽  
Laser Ablation ◽  
Inductively Coupled Plasma ◽  
Promising Alternative ◽  
Inductively Coupled ◽  
Icp Ms ◽  
Direct Sampling ◽  
Ionisation Mass Spectrometry ◽  
Plasma Mass Spectrometry ◽  
Ionisation Mass

At the beginning of the age of laser-ionisation mass spectrometry (LIMS) increasing numbers of publications were observed. However, later the method began to run into obstacles associated with poor reproducibility of analysis and large variations in elemental sensitivities so that the wide interest of the scientific community in the method faded away. However, the results described here show that the current knowledge of laser plasma processes, together with modern technical solutions to ion separation and quantification with time-of-flight (ToF) mass spectrometry, allow one to overcome the above-mentioned obstacles in LIMS. Thus, the performance in direct-sampling solid analysis demonstrated by the LAMAS-10M instrument is similar to that typically obtained by laser ablation/inductively-coupled plasma mass spectrometry (LA-ICP-MS) and glow-discharge mass spectrometry (GD-MS) methods. At the same time, there are additional advantages, including compactness of the instrument, absence of the need for expensive consumables and freedom from mass line interferences. Direct-sampling elemental LIMS is discussed as a promising alternative to LA-ICP-MS and GD-MS. Existing and prospective approaches to designing direct-sampling laser-ionisation mass spectrometers are theoretically justified. Factors affecting the main performance criteria, such as reproducibility, correctness, variations of relative sensitivity factors, linear dynamic range and resolution are considered. The demonstrated reproducibility, resolution, low-ppb limit of detection and one order-of-magnitude variation in elemental sensitivity are not the limit for direct-sampling laser-ionisation mass spectrometry of solid samples. Ways of improving LI-ToF-MS instrumental performance are discussed and theoretically justified.

Synthesis, structure, and condensed-phase reactivity of [Ag3(μ3-H)(μ3-BH4)LPh3](BF4) (LPh = bis(diphenylphosphino)amine) with CS2

2018 ◽  
Vol 47 (41) ◽  
pp. 14713-14725 ◽  
Author(s):  
Howard Z. Ma ◽  
Jonathan M. White ◽  
Roger J. Mulder ◽  
Gavin E. Reid ◽  
Allan J. Canty ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Condensed Phase ◽  
Esi Ms ◽  
Electrospray Ionisation ◽  
Electrospray Ionisation Mass Spectrometry ◽  
Ionisation Mass Spectrometry ◽  
Ionisation Mass

Electrospray ionisation mass spectrometry (ESI-MS) was used to monitor the reaction of AgBF4, bis(diphenylphosphino)amine (dppa = (Ph2P)2NH = LPh) and NaBH4 in acetonitrile.

scholarly journals Multi-Modal Mass Spectrometric Imaging of Uveal Melanoma

Metabolites ◽  
2021 ◽  
Vol 11 (8) ◽  
pp. 560
Author(s):  
Laura M. Cole ◽  
Joshua Handley ◽  
Emmanuelle Claude ◽  
Catherine J. Duckett ◽  
Hardeep S. Mudhar ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Inductively Coupled Plasma ◽  
Cancer Metastasis ◽  
Inductively Coupled ◽  
Icp Ms ◽  
Ionisation Mass Spectrometry ◽  
Plasma Mass Spectrometry ◽  
Tumour Periphery ◽  
Modal Mass

Matrix assisted laser desorption ionisation mass spectrometry imaging (MALDI-MSI), was used to obtain images of lipids and metabolite distribution in formalin fixed and embedded in paraffin (FFPE) whole eye sections containing primary uveal melanomas (UM). Using this technique, it was possible to obtain images of lysophosphatidylcholine (LPC) type lipid distribution that highlighted the tumour regions. Laser ablation inductively coupled plasma mass spectrometry images (LA-ICP-MS) performed on UM sections showed increases in copper within the tumour periphery and intratumoural zinc in tissue from patients with poor prognosis. These preliminary data indicate that multi-modal MSI has the potential to provide insights into the role of trace metals and cancer metastasis.

Chemical profile of mango (Mangifera indica L.) using electrospray ionisation mass spectrometry (ESI-MS)

2016 ◽  
Vol 204 ◽  
pp. 37-45 ◽  
Author(s):  
Bruno G. Oliveira ◽  
Helber B. Costa ◽  
José A. Ventura ◽  
Tamara P. Kondratyuk ◽  
Maria E.S. Barroso ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Mangifera Indica ◽  
Chemical Profile ◽  
Esi Ms ◽  
Electrospray Ionisation ◽  
Electrospray Ionisation Mass Spectrometry ◽  
Ionisation Mass Spectrometry ◽  
Ionisation Mass
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