Exosome-mediated microRNA-497 delivery for anti-cancer therapy in a microfluidic 3D lung cancer model

Lab on a Chip ◽  
2020 ◽  
Vol 20 (3) ◽  
pp. 548-557 ◽  
Author(s):  
Kyeongsoo Jeong ◽  
Yeong Jun Yu ◽  
Jae Young You ◽  
Won Jong Rhee ◽  
Jeong Ah Kim
Keyword(s):  
Lung Cancer ◽  
Cancer Therapy ◽  
Culture System ◽  
3D Cell Culture ◽  
Targeted Cancer Therapy ◽  
Cell Culture System ◽  
Cancer Model ◽  
Anti Cancer ◽  
Lung Cancer Model ◽  
Cost Efficient

A 3D cell culture system that mimics the lung cancer microenvironment was used to investigate the effect of exosomes encapsulating miR-497 on tumor growth and angiogenesis, and could be a predictive, cost-efficient translational tool to develop targeted cancer therapy.

Abstract 316: Development of a novel 3D cancer model by cultivation of malignant effusions in a 3D cell culture system

2015 ◽  
Author(s):  
Arno Amann ◽  
Marit Zwierzina ◽  
Julia M. Huber ◽  
Gabriele Gamerith ◽  
Stefan Koeck ◽  
...  
Keyword(s):  
Cell Culture ◽  
Culture System ◽  
3D Cell Culture ◽  
Cell Culture System ◽  
Cancer Model ◽  
Malignant Effusions

scholarly journals Development of an Innovative 3D Cell Culture System to Study Tumour - Stroma Interactions in Non-Small Cell Lung Cancer Cells

PLoS ONE ◽  
2014 ◽  
Vol 9 (3) ◽  
pp. e92511 ◽  
Author(s):  
Arno Amann ◽  
Marit Zwierzina ◽  
Gabriele Gamerith ◽  
Mario Bitsche ◽  
Julia M. Huber ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Cell Culture ◽  
Small Cell Lung Cancer ◽  
Cancer Cells ◽  
Culture System ◽  
3D Cell Culture ◽  
Small Cell ◽  
Cell Culture System ◽  
Tumour Stroma ◽  
Small Cell Lung

scholarly journals Modest Anti-Cancer Activity of a Bile Acid Acylated Heparin Derivative in a PC14PE6 Induced Orthotopic Lung Cancer Model

2009 ◽  
Vol 41 (2) ◽  
pp. 80 ◽  
Author(s):  
Zheng Yun Cui ◽  
Min Jae Park ◽  
Jeeyun Lee ◽  
Jin Seok Ahn ◽  
Myung Ju Ahn ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Bile Acid ◽  
Cancer Model ◽  
Anti Cancer ◽  
Lung Cancer Model ◽  
Heparin Derivative ◽  
Cancer Activity

scholarly journals Metabolic response of lung cancer cells to radiation in a paper-based 3D cell culture system

Biomaterials ◽  
2016 ◽  
Vol 95 ◽  
pp. 47-59 ◽  
Author(s):  
Karen A. Simon ◽  
Bobak Mosadegh ◽  
Kyaw Thu Minn ◽  
Matthew R. Lockett ◽  
Marym R. Mohammady ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Cell Culture ◽  
Cancer Cells ◽  
Culture System ◽  
Metabolic Response ◽  
3D Cell Culture ◽  
Lung Cancer Cells ◽  
Cell Culture System

scholarly journals DNA vaccine elicits an efficient antitumor response by targeting the mutant Kras in a transgenic mouse lung cancer model

Gene Therapy ◽  
2014 ◽  
Vol 21 (10) ◽  
pp. 888-896 ◽  
Author(s):  
T-Y Weng ◽  
M-C Yen ◽  
C-T Huang ◽  
J-J Hung ◽  
Y-L Chen ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Transgenic Mouse ◽  
Dna Vaccine ◽  
Mouse Lung ◽  
Cancer Model ◽  
Antitumor Response ◽  
Lung Cancer Model

Refinement of an Orthotopic Lung Cancer Model in the Nude Rat

2001 ◽  
Vol 38 (5) ◽  
pp. 483-490 ◽  
Author(s):  
T. H. March ◽  
P. G. Marron-Terada ◽  
S. A. Belinsky
Keyword(s):  
Lung Cancer ◽  
Cancer Model ◽  
Nude Rat ◽  
Lung Cancer Model
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