Automated serial dilutions for high-dynamic-range assays enabled by fill-level-coupled valving in centrifugal microfluidics

Lab on a Chip ◽  
2019 ◽  
Vol 19 (13) ◽  
pp. 2205-2219 ◽  
Author(s):  
Peter Juelg ◽  
Mara Specht ◽  
Elena Kipf ◽  
Michael Lehnert ◽  
Cornelia Eckert ◽  
...  

Time-independent, serial valving under rotation on centrifugal microfluidic platforms by a fill-level-coupled temperature change rate (FLC-TCR) actuated principle.

Lab on a Chip ◽  
2018 ◽  
Vol 18 (2) ◽  
pp. 362-370 ◽  
Author(s):  
S. Hin ◽  
N. Paust ◽  
M. Keller ◽  
M. Rombach ◽  
O. Strohmeier ◽  
...  

Temperature change rate as actuation principle for a bubble mixer in centrifugal microfluidics minimizes external means required. We applied the new bubble mixer to the rehydration of dry reagents for nucleic acid amplification.


Lab on a Chip ◽  
2017 ◽  
Vol 17 (5) ◽  
pp. 864-875 ◽  
Author(s):  
M. Keller ◽  
G. Czilwik ◽  
J. Schott ◽  
I. Schwarz ◽  
K. Dormanns ◽  
...  

Thermally induced underpressure for temperature change rate (TCR) actuated siphon valving, which is controlled by the rotational frequency. The TCR actuated siphon valve makes use of already present air vents for implementation at no additional cost in centrifugal microfluidics.


1986 ◽  
Vol 133 (1) ◽  
pp. 26
Author(s):  
J. Mellis ◽  
G.R. Adams ◽  
K.D. Ward

2009 ◽  
Vol 35 (2) ◽  
pp. 113-122 ◽  
Author(s):  
Ke-Hu YANG ◽  
Jing JI ◽  
Jian-Jun GUO ◽  
Wen-Sheng YU

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