scholarly journals A quantitative nanoparticle extraction method for microsecond time resolved single-particle ICP-MS data in the presence of a high background

2019 ◽  
Vol 34 (8) ◽  
pp. 1571-1580 ◽  
Author(s):  
Darya Mozhayeva ◽  
Carsten Engelhard
Keyword(s):  
Time Resolution ◽  
Single Particle ◽  
Extraction Method ◽  
New Method ◽  
Time Resolved ◽  
High Background ◽  
Icp Ms ◽  
Dissolved Ions

A new method for the quantification of dissolved ions and nanoparticles in mixtures with SP-ICP-MS with microsecond time resolution.

scholarly journals Toward Real-Time Monitoring and Control of Single Nanoparticle Properties with a Microbubble Resonator Spectrometer

2019 ◽  
Author(s):  
Levi Hogan ◽  
Erik Horak ◽  
Jonathan Ward ◽  
Kassandra Knapper ◽  
Síle Nic Chormaic ◽  
...  
Keyword(s):  
Single Particle ◽  
Stable Solution ◽  
New Method ◽  
Monitoring And Control ◽  
Experimental Conditions ◽  
Widespread Application ◽  
Time Resolved ◽  
Biologically Relevant ◽  
Rapid Acquisition ◽  
Free Environment

<p></p><p></p><p>Optical microresonators have widespread application at the frontiers of nanophotonic technology, driven by their ability to confine light to the nanoscale and enhance light-matter interactions. Microresonators form the heart of a new method for single-particle photothermal absorption spectroscopy, whereby the microresonators act as microscale thermometers to detect the heat dissipated by optically pumped, non-luminescent nanoscopic targets. However, translation of this technology to chemically dynamic systems requires a platform that is mechanically stable, solution compatible, and visibly transparent. We report microbubble absorption spectrometers as a new and versatile platform that meets these requirements. Microbubbles integrate a two-port microfluidic device within a Whispering Gallery Mode (WGM) microresonator, allowing for the facile exchange of chemical reagents within the resonator’s interior while maintaining a solution-free environment on its exterior. We first leverage these qualities to investigate the photo-activated etching of single gold nanorods by ferric chloride, providing a new method for rapid acquisition of spatial and morphological information about nanoparticles as they undergo chemical reactions. We then demonstrate the ability to control nanorod orientation within a microbubble through optically exerted torque, a new route toward the construction of hybrid photonic-plasmonic systems. Critically, the reported platform advances microresonator spectrometer technology by permitting room-temperature, aqueous experimental conditions, opening a regime of time-resolved single-particle experiments on non-emissive, nanoscale analytes engaged in catalytically and biologically relevant chemical dynamics.</p><p></p><p></p>

Toward Real-Time Monitoring and Control of Single Nanoparticle Properties with a Microbubble Resonator Spectrometer

2019 ◽  
Author(s):  
Levi Hogan ◽  
Erik Horak ◽  
Jonathan Ward ◽  
Kassandra Knapper ◽  
Síle Nic Chormaic ◽  
...  
Keyword(s):  
Single Particle ◽  
Stable Solution ◽  
New Method ◽  
Monitoring And Control ◽  
Experimental Conditions ◽  
Widespread Application ◽  
Time Resolved ◽  
Biologically Relevant ◽  
Rapid Acquisition ◽  
Free Environment

<p></p><p></p><p>Optical microresonators have widespread application at the frontiers of nanophotonic technology, driven by their ability to confine light to the nanoscale and enhance light-matter interactions. Microresonators form the heart of a new method for single-particle photothermal absorption spectroscopy, whereby the microresonators act as microscale thermometers to detect the heat dissipated by optically pumped, non-luminescent nanoscopic targets. However, translation of this technology to chemically dynamic systems requires a platform that is mechanically stable, solution compatible, and visibly transparent. We report microbubble absorption spectrometers as a new and versatile platform that meets these requirements. Microbubbles integrate a two-port microfluidic device within a Whispering Gallery Mode (WGM) microresonator, allowing for the facile exchange of chemical reagents within the resonator’s interior while maintaining a solution-free environment on its exterior. We first leverage these qualities to investigate the photo-activated etching of single gold nanorods by ferric chloride, providing a new method for rapid acquisition of spatial and morphological information about nanoparticles as they undergo chemical reactions. We then demonstrate the ability to control nanorod orientation within a microbubble through optically exerted torque, a new route toward the construction of hybrid photonic-plasmonic systems. Critically, the reported platform advances microresonator spectrometer technology by permitting room-temperature, aqueous experimental conditions, opening a regime of time-resolved single-particle experiments on non-emissive, nanoscale analytes engaged in catalytically and biologically relevant chemical dynamics.</p><p></p><p></p>

scholarly journals Time-resolved ICP-MS Measurement: a New Method for Elemental and Multiparametric Analysis of Single Cells

2014 ◽  
Vol 30 (2) ◽  
pp. 219-224 ◽  
Author(s):  
Shin-ichi MIYASHITA ◽  
Alexander S. GROOMBRIDGE ◽  
Shin-ichiro FUJII ◽  
Akiko TAKATSU ◽  
Koichi CHIBA ◽  
...  
Keyword(s):  
Single Cells ◽  
New Method ◽  
Time Resolved ◽  
Multiparametric Analysis ◽  
Icp Ms

A new peak recognition algorithm for detection of ultra-small nano-particles by single particle ICP-MS using rapid time resolved data acquisition on a sector-field mass spectrometer

2015 ◽  
Vol 30 (8) ◽  
pp. 1723-1729 ◽  
Author(s):  
Jani Tuoriniemi ◽  
Geert Cornelis ◽  
Martin Hassellöv
Keyword(s):  
Detection Limit ◽  
Data Acquisition ◽  
Single Particle ◽  
Recognition Algorithm ◽  
Nano Particles ◽  
Field Mass ◽  
Time Resolved ◽  
Icp Ms ◽  
Peak Recognition ◽  
Rapid Data Acquisition

The size detection limit of single particle ICP-MS is improved by rapid data acquisition combined with a new peak recognition algorithm.

scholarly journals Fast time-resolved aerosol collector: proof of concept

2010 ◽  
Vol 3 (5) ◽  
pp. 1377-1384
Author(s):  
X.-Y. Yu ◽  
J. P. Cowin ◽  
M. J. Iedema ◽  
H. Ali
Keyword(s):  
Time Resolution ◽  
Single Particle ◽  
Particle Methods ◽  
Particle Analysis ◽  
Fast Time ◽  
Time Resolved ◽  
On Line ◽  
Real Time Information ◽  
Spatial Locations

Abstract. Atmospheric particles can be collected in the field on substrates for subsequent laboratory analysis via chemically sensitive single particle methods such as scanning electron microscopy with energy dispersive x-ray analysis. With moving substrates time resolution of seconds to minutes can be achieved. In this paper, we demonstrate how to increase the time resolution when collecting particles on a substrate to a few milliseconds to provide real-time information. Our fast time-resolved aerosol collector ("Fast-TRAC") microscopically observes the particle collection on a substrate and records an on-line video. Particle arrivals are resolved to within a single frame (4–17 ms in this setup), and the spatial locations are matched to the subsequent single particle analysis. This approach also provides in-situ information on particle size and number concentration. Applications are expected in airborne studies of cloud microstructure, pollution plumes, and surface long-term monitoring.

scholarly journals Fast time-resolved aerosol collector: proof of concept

2010 ◽  
Vol 3 (3) ◽  
pp. 2515-2534
Author(s):  
X.-Y. Yu ◽  
J. P. Cowin ◽  
M. J. Iedema ◽  
H. Ali
Keyword(s):  
Time Resolution ◽  
Single Particle ◽  
Particle Methods ◽  
Particle Analysis ◽  
Fast Time ◽  
Time Resolved ◽  
On Line ◽  
Real Time Information ◽  
Spatial Locations

Abstract. Atmospheric particles can be collected in the field on substrates for subsequent laboratory analysis via chemically sensitive single particle methods such as scanning electron microscopy with energy dispersive x-ray analysis. With moving substrates time resolution of seconds to minutes can be achieved. In this paper, we demonstrate how to increase the time resolution when collecting particles on a substrate to a few milliseconds to provide real-time information. Our fast time-resolved aerosol collector ("Fast-TRAC") microscopically observes the particle collection on a substrate and records an on-line video. Particle arrivals are resolved to within a single frame (4–17 ms in this setup), and the spatial locations are matched to the subsequent single particle analysis. This approach also provides in-situ information on particle size and number concentration. Applications are expected in airborne studies of cloud microstructure, pollution plumes, and surface long-term monitoring.

scholarly journals Capabilities of fast data acquisition with microsecond time resolution in inductively coupled plasma mass spectrometry and identification of signal artifacts from millisecond dwell times during detection of single gold nanoparticles

2016 ◽  
Vol 31 (1) ◽  
pp. 135-144 ◽  
Author(s):  
I. Strenge ◽  
C. Engelhard
Keyword(s):  
Mass Spectrometry ◽  
Gold Nanoparticles ◽  
Data Acquisition ◽  
Time Resolution ◽  
Single Particle ◽  
Inductively Coupled Plasma ◽  
Inductively Coupled ◽  
Fast Data Acquisition ◽  
Icp Ms ◽  
Plasma Mass Spectrometry

In this paper, a home-built DAQ featuring microsecond time resolution is used to demonstrate advantages of fast data acquisition and to uncover potential artifacts in single-particle ICP-MS.

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