Soyasaponins A1 and A2 exert anti-atherosclerotic functionalities by decreasing hypercholesterolemia and inflammation in high fat diet (HFD)-fed ApoE−/− mice

2020 ◽  
Vol 11 (1) ◽  
pp. 253-269 ◽  
Author(s):  
Qunying Xie ◽  
Fei Xiong ◽  
Xinglong Wu ◽  
Junbin Chen ◽  
Xiangfu Gu ◽  
...  

To the best of our knowledge, this study firstly shows that soyasaponins (A1 & A2) exhibit antiatherosclerotic bioactivities by improving the serum lipid profile and reducing TLR4-/MyD88-/NF-κB-mediated inflammations in high fat diet-fed ApoE−/− mice.

3 Biotech ◽  
2021 ◽  
Vol 11 (6) ◽  
Author(s):  
Mahesh P. Patil ◽  
Jayesh J. Ahire ◽  
Ulhas K. Patil ◽  
Bharat Bhushan ◽  
Bhushan L. Chaudhari

2016 ◽  
Vol 81 (7) ◽  
pp. H1840-H1845 ◽  
Author(s):  
Byoung-Mok Kim ◽  
Jae-Ho Park ◽  
Dong-Soo Kim ◽  
Young-Myung Kim ◽  
Joon-Young Jun ◽  
...  

2010 ◽  
Vol 24 (S1) ◽  
Author(s):  
Paula Daniela Perris ◽  
María Susana Feliu ◽  
Inés Fernandez ◽  
Nora Slobodianik

Author(s):  
Maya Bassil ◽  
Costantine F Daher ◽  
Mohammad Mroueh ◽  
Nadine Zeeni

2016 ◽  
Vol 2016 ◽  
pp. 1-11 ◽  
Author(s):  
Dong-Seon Kim ◽  
Seung-Hyung Kim ◽  
Jimin Cha

The antiobesity effects of several different combinations of extracts (BS) prepared from two plants,Phyllostachys pubescensleaf (bamboo leaf: BL) andScutellaria baicalensisroot (SB), were investigated using a high fat diet (HFD) induced obese mouse model. In order to find the most effective mixture among the mixtures of the two plant extracts, experimental preparations were made by combining BL and SB by different proportions of 3 : 1 (BS31), 2 : 1 (BS21), 1 : 1 (BS11), 1 : 2 (BS12), and 1 : 3 (BS13). Body weight, weight of adipose tissues, size of adipocytes, levels of glucose, leptin and adiponectin, and lipid profile in serum, and fat accumulation in liver were investigated. We have found that BS21 is the most effective in antiobesity among the five mixtures investigated, indicated by reduction in body weight gain, total mass of adipose tissue, and the size of adipocyte. In addition, BS21 has shown to be beneficial in serum lipid profile, levels of glucose, leptin, and adiponectin in serum, and fat accumulation in liver. By chromatographic separation of BS21, the two maker compounds, isoorientin and baicalin, were identified and quantified for the standardization of BS21.


2019 ◽  
Vol 11 (4) ◽  
pp. 836-841 ◽  
Author(s):  
Rohan S Phatak ◽  
Chitra C Khanwelkar ◽  
Somnath M Matule ◽  
Kailas D Datkhile ◽  
Anup S Hendre

2001 ◽  
Vol 120 (5) ◽  
pp. A576-A576
Author(s):  
E FOGEL ◽  
T IMPERIALE ◽  
B DEVERAUX ◽  
S SHERMAN ◽  
J WATKINS ◽  
...  

2007 ◽  
Vol 16 (1) ◽  
Author(s):  
D Sarkar ◽  
SA Latif ◽  
MM Uddin ◽  
J Aich ◽  
SR Sutradhar ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document