α-Lactalbumin and chitosan core–shell nanoparticles: resveratrol loading, protection, and antioxidant activity

2020 ◽  
Vol 11 (2) ◽  
pp. 1525-1536 ◽  
Author(s):  
Yuexiang Liu ◽  
Luyu Gao ◽  
Jiang Yi ◽  
Yuting Fan ◽  
Xuli Wu ◽  
...  

Resveratrol (RES)-loaded protein–polysaccharide nanoparticles were fabricated through simple electrostatic interactions with oppositely charged α-lactalbumin (ALA) and chitosan (CHI) with a mass ratio of 5 : 1 without the addition of NaCl at pH 6.5.

Soft Matter ◽  
2012 ◽  
Vol 8 (36) ◽  
pp. 9412 ◽  
Author(s):  
Miroslav Štěpánek ◽  
Juraj Škvarla ◽  
Mariusz Uchman ◽  
Karel Procházka ◽  
Borislav Angelov ◽  
...  

2008 ◽  
Vol 254 (6) ◽  
pp. 1684-1690 ◽  
Author(s):  
Youli Qi ◽  
Miao Chen ◽  
Shan Liang ◽  
Wu Yang ◽  
Jing Zhao

2020 ◽  
Author(s):  
Jakob Hübner ◽  
Vincent Pichot ◽  
Emeline Lobry ◽  
Tanja Deckert-Gaudig ◽  
Volker Deckert ◽  
...  

<p>Mixtures of RDX and TNT or hexolite mixtures are well known precursors for nanodiamond detonation syntheses. In this study diverse nanoscale hexolite mixtures varying in mass ratios of RDX and TNT are synthesized via Spray Flash Evaporation. The hexolite mixtures are characterized by confocal Raman spectroscopy and tip-enhanced Raman spectroscopy (TERS) to obtain information about their molecular structure composition. The marker bands of pristine RDX and TNT enable the identification and distinction of both compounds in the Raman spectra. Confocal Raman spectroscopy indicates an intermixture of RDX and TNT molecules on the nanoscale since both marker bands are detected in all spectra. TERS investigations of single hexolite particles reveal that the particle surfaces are mainly composed of TNT. The comparison of confocal Raman and TERS results suggests that (depending on the mass ratio) hexolite particles are either inhomogeneous patchy RDX/TNT nanoparticles or anisotropic RDX/TNT core-shell nanoparticles. A building mechanism to explain the formation/growth of those nanoparticles is derived from the spectroscopic data and the dynamics of the SFE process. Finally, a correlation between the TNT shell thickness, the symmetry of the anisotropic hexolite precursor nanoparticles, and the resulting nanodiamond sizes is discussed in detail.</p>


Materials ◽  
2021 ◽  
Vol 14 (9) ◽  
pp. 2304
Author(s):  
Anna Pajor-Świerzy ◽  
Dawid Staśko ◽  
Radosław Pawłowski ◽  
Grzegorz Mordarski ◽  
Alexander Kamyshny ◽  
...  

The effect of polydispersity of nickel-silver core-shell nanoparticles (Ni-Ag NPs) on the conductivity of ink coatings was studied. Ni-Ag NPs of various average diameters (100, 220, and 420 nm) were synthesized and utilized for the preparation of conductive inks composed of monodisperse NPs and their polydisperse mixtures. The shell thickness of synthesized Ni-Ag NPs was found to be in the range of 10–20 nm and to provide stability of a core metal to oxidation for at least 6 months. The conductivity of metallic films formed by inks with monodisperse Ni-Ag NPs was compared with those formed by polydisperse inks. In all cases, the optimal conditions for the formation of conductive patterns (weight ratio of monodisperse NPs for polydisperse composition, the concentration of the wetting agent, sintering temperature, and duration) were determined. It was found that metallic films formed by polydisperse ink containing 100, 220, and 420 nm Ni-Ag NPs with a mass ratio of 1:1.5:0.5, respectively, are characterized by the lowest resistivity, 10.9 µΩ·cm, after their thermal post-coating sintering at 300 °C for 30 min that is only 1.6 higher than that of bulk nickel.


2014 ◽  
Vol 67 (1) ◽  
pp. 142 ◽  
Author(s):  
You Wei Zhang ◽  
Yan Chen ◽  
Jiong Xin Zhao

Antibacterial core–shell nanoparticles based on poly(hexamethylene guanidine hydrochloride) (PHMG) oligomers and poly(acrylic acid) (PAA) networks are efficiently fabricated via a facile one-step co-polymerization of acrylic acid and N,N′-methylenebisacrylamide on PHMG templates in aqueous solution. Dynamic light scattering, Fourier-transform infrared spectroscopy, and transmission electron microscopy observations were used to characterize the size, morphology, and structure of the nanoparticles, as well as the interactions between the components. Also, the stability of the nanoparticle dispersion against storage, pH value, salt, and temperature was investigated. The results show that the crosslinked PAA/PHMG nanoparticles are stabilized by electrostatic interactions. The core–shell structure of the nanoparticles was confirmed by transmission electron microscopy observation. The size of the nanoparticles increases substantially with extension of storage or with increase of the salt concentration. The nanoparticle dispersion is stable in a pH range of 2.0–4.0. The size change of the nanoparticles with pH of the medium is parabolic, and the minimum size is reached at pH 3.0. A rise of temperature leads to a slight and recoverable size increase of the nanoparticles. Antibacterial efficiency was evaluated quantitatively against Escherichia coli and Staphylococcus aureus by the plating method according to Standard JC/T 897–2002. The antibacterial activity against these two bacteria are both above 99.0 % at a nanoparticle concentration of 5 mg mL–1. This makes the nanoparticle dispersion a good candidate for the application of antibacterial water-based coatings and textiles coating.


Nano LIFE ◽  
2012 ◽  
Vol 02 (01) ◽  
pp. 1250002 ◽  
Author(s):  
MINGBIN ZHENG ◽  
PING GONG ◽  
DONGXUE JIA ◽  
CUIFANG ZHENG ◽  
YIFAN MA ◽  
...  

We reported the development of multifunctional poly (lactic-co-glycolic acid) (PLGA)-lecithin-polyethylene glycol (PEG) core-shell nanoparticles (NPs) that combined the beneficial properties of liposome and polymeric NPs for chemotherapeutics delivery. The particle size, surface charge and surface functional groups were easily tunable in highly reproducible manner by various formulation parameters such as lipid/polymer, 1, 2-distearoyl-sn-glycero-3-phosphoethanolamine (DSPE)-PEG- COOH /lecithin, DSPE-PEG- COOH /DSPE-PEG- NH2 mass ratio and modification of terminal groups of DSPE-PEG. We encapsulated model chemotherapy drug, hydrophilic cisplatin (DDP) or hydrophobic DDP prodrug, in the NPs and showed high encapsulation efficiency, excellent stability, specific FA targeting recognition for MCF-7 cells with over FA receptors expression and pretty cytotoxicity. Such PLGA–lecithin–PEG core-shell nanoparticles (NPs) were proved to be a promising drug delivery nanocarrier for cancer-targeted therapy.


2020 ◽  
Author(s):  
Jakob Hübner ◽  
Vincent Pichot ◽  
Emeline Lobry ◽  
Tanja Deckert-Gaudig ◽  
Volker Deckert ◽  
...  

<p>Mixtures of RDX and TNT or hexolite mixtures are well known precursors for nanodiamond detonation syntheses. In this study diverse nanoscale hexolite mixtures varying in mass ratios of RDX and TNT are synthesized via Spray Flash Evaporation. The hexolite mixtures are characterized by confocal Raman spectroscopy and tip-enhanced Raman spectroscopy (TERS) to obtain information about their molecular structure composition. The marker bands of pristine RDX and TNT enable the identification and distinction of both compounds in the Raman spectra. Confocal Raman spectroscopy indicates an intermixture of RDX and TNT molecules on the nanoscale since both marker bands are detected in all spectra. TERS investigations of single hexolite particles reveal that the particle surfaces are mainly composed of TNT. The comparison of confocal Raman and TERS results suggests that (depending on the mass ratio) hexolite particles are either inhomogeneous patchy RDX/TNT nanoparticles or anisotropic RDX/TNT core-shell nanoparticles. A building mechanism to explain the formation/growth of those nanoparticles is derived from the spectroscopic data and the dynamics of the SFE process. Finally, a correlation between the TNT shell thickness, the symmetry of the anisotropic hexolite precursor nanoparticles, and the resulting nanodiamond sizes is discussed in detail.</p>


2012 ◽  
Vol 27 (1) ◽  
pp. 95-101
Author(s):  
Shi-Bin LIU ◽  
Chun-Ying YANG ◽  
Zhong-Lin ZHANG ◽  
Dong-Hong DUAN ◽  
Xiao-Gang HAO ◽  
...  

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