Processed Aloe vera gel attenuates non-steroidal anti-inflammatory drug (NSAID)-induced small intestinal injury by enhancing mucin expression

2019 ◽  
Vol 10 (9) ◽  
pp. 6088-6097 ◽  
Author(s):  
Min Woo Kim ◽  
Ju-Hee Kang ◽  
Eunju Shin ◽  
Kyu-Suk Shim ◽  
Min Jung Kim ◽  
...  
Keyword(s):  
Adverse Effects ◽  
Aloe Vera ◽  
Intestinal Damage ◽  
Inflammatory Drug ◽  
Aloe Vera Gel ◽  
Small Intestinal Injury ◽  
Mucin Expression ◽  
Gel Treatment ◽  
Small Intestinal ◽  
Potential Strategy

NSAIDs-induced intestinal damage is one of the most common adverse effects by medication. Here, we suggest processed Aloe vera gel treatment as a potential strategy to attenuate NSAID-induced intestinal damage via enhancing mucin expression.

scholarly journals Involvement of gliadin, a component of wheat gluten, in increased intestinal permeability leading to non-steroidal anti-inflammatory drug-induced small-intestinal damage

PLoS ONE ◽  
2019 ◽  
Vol 14 (2) ◽  
pp. e0211436 ◽  
Author(s):  
Sunao Shimada ◽  
Tetsuya Tanigawa ◽  
Toshio Watanabe ◽  
Akinobu Nakata ◽  
Naoki Sugimura ◽  
...  
Keyword(s):  
Intestinal Permeability ◽  
Wheat Gluten ◽  
Intestinal Damage ◽  
Drug Induced ◽  
Inflammatory Drug ◽  
Small Intestinal ◽  
Anti Inflammatory

Mo1031 PROTECTIVE ROLE OF THE PRO-RESOLVING LIPID MEDIATOR RESOLVIN D1 IN NONSTEROIDAL ANTI-INFLAMMATORY DRUG-INDUCED SMALL INTESTINAL DAMAGE

2020 ◽  
Vol 158 (6) ◽  
pp. S-762
Author(s):  
Takuya Kuzumoto ◽  
Tetsuya Tanigawa ◽  
Hiroyuki Kitamura ◽  
Akira Higashimori ◽  
Yuji Nadatani ◽  
...  
Keyword(s):  
Protective Role ◽  
Lipid Mediator ◽  
Intestinal Damage ◽  
Resolvin D1 ◽  
Drug Induced ◽  
Inflammatory Drug ◽  
Small Intestinal ◽  
Anti Inflammatory

Risk factors for severe nonsteroidal anti-inflammatory drug-induced small intestinal damage

2013 ◽  
Vol 45 (5) ◽  
pp. 390-395 ◽  
Author(s):  
Toshio Watanabe ◽  
Tetsuya Tanigawa ◽  
Yuji Nadatani ◽  
Yasuaki Nagami ◽  
Satoshi Sugimori ◽  
...  
Keyword(s):  
Risk Factors ◽  
Intestinal Damage ◽  
Drug Induced ◽  
Inflammatory Drug ◽  
Small Intestinal ◽  
Anti Inflammatory

Preventive effect of agaro-oligosaccharides on non-steroidal anti-inflammatory drug-induced small intestinal injury in mice

2014 ◽  
Vol 29 (2) ◽  
pp. 310-317 ◽  
Author(s):  
Yasuki Higashimura ◽  
Yuji Naito ◽  
Tomohisa Takagi ◽  
Yuko Tanimura ◽  
Katsura Mizushima ◽  
...  
Keyword(s):  
Intestinal Injury ◽  
Preventive Effect ◽  
Drug Induced ◽  
Inflammatory Drug ◽  
Small Intestinal Injury ◽  
Small Intestinal ◽  
Anti Inflammatory

scholarly journals An Innovation for Retarded Healing Process of a Chronic Ulcer by Aloe Vera Gel Treatment

2016 ◽  
Vol 16 (2) ◽  
pp. 45 ◽  
Author(s):  
Majid Avijgan ◽  
Mahtab Avijgan ◽  
Atousa Hakamifard ◽  
Niloufar Razavi
Keyword(s):  
Potassium Permanganate ◽  
Conventional Treatment ◽  
Healing Process ◽  
Aloe Vera ◽  
Complete Healing ◽  
Response To Therapy ◽  
Chronic Ulcer ◽  
Alternative Methods ◽  
Aloe Vera Gel ◽  
Gel Treatment

In some cases of chronic ulcers of soft tissue cannot be treated by conventional treatment methods. In recent years some alternative methods have been proposed for treatment of such ulcers on the basis of Traditional Iranian (Persian) Medicine. This reports a case of chronic ulcer treatment by using <em>Aloe vera</em> gel. The ulcer was caused by car accident and in spite of using conventional treatment the injury remained for 60 days without appropriate response to therapy. Because of stopping in healing process by Aloe vera gel, this was discontinued and potassium permanganate has been used. After drying the ulcer using the alternative method of <em>Aloe vera</em> gel and potassium permanganate together has been applied and then the <em>Aloe vera</em> gel was used until the complete healing of ulcer. The delayed healing process of <em>Aloe vera</em> gel raise the question whether it is solely effective in complete healing of chronic ulcer or requires adjuvant therapies. Although <em>Aloe vera</em> is effective in healing process of chronic ulcer but sometimes it may be ineffective so that we are obliged to use potassium permanganate as an adjuvant drug which is presented by this case report.

scholarly journals Comparison of TGF-β1 in corneal laceration with or without Aloe vera gel treatment

2021 ◽  
Vol 11 (1) ◽  
pp. 120-124
Author(s):  
Nur Atik ◽  
Muhamad Arif Rachman Sururi ◽  
Raden Angga Kartiwa
Keyword(s):  
Aloe Vera ◽  
Aloe Vera Gel ◽  
Gel Treatment ◽  
Tgf Β1 ◽  
Corneal Laceration
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