Enzymatically modified isoquercitrin promotes energy metabolism through activating AMPKα in male C57BL/6 mice

2019 ◽  
Vol 10 (8) ◽  
pp. 5188-5202 ◽  
Author(s):  
Hao Jiang ◽  
Yasukiyo Yoshioka ◽  
Sihao Yuan ◽  
Yuko Horiuchi ◽  
Yoko Yamashita ◽  
...  
Keyword(s):  
Energy Metabolism ◽  
Food Additive ◽  
Ampk Phosphorylation ◽  
Quercetin Glycoside ◽  
Potential Food

Enzymatically modified isoquercitrin (EMIQ), a quercetin glycoside with a greater bioavailability, is a potential food additive for the regulation of energy metabolism through AMPK phosphorylation.

The food additive BHA modifies energy metabolism in the perfused rat liver

2018 ◽  
Vol 299 ◽  
pp. 191-200 ◽  
Author(s):  
Vanesa de Oliveira Pateis ◽  
Lívia Bracht ◽  
Lorena dos Santos Castro ◽  
Gabriela Bueno Franco Salla ◽  
Jurandir Fernando Comar ◽  
...  
Keyword(s):  
Energy Metabolism ◽  
Rat Liver ◽  
Food Additive ◽  
Perfused Rat Liver

scholarly journals Assessment of Nano Cellulose from Peach Palm Residue as Potential Food Additive: Part II: Preliminary Studies

2014 ◽  
Vol 52 (9) ◽  
pp. 5641-5650 ◽  
Author(s):  
Dayanne Regina Mendes Andrade ◽  
Márcia Helena Mendonça ◽  
Cristiane Vieira Helm ◽  
Washington L. E. Magalhães ◽  
Graciela Ines Bonzon de Muniz ◽  
...  
Keyword(s):  
Food Additive ◽  
Peach Palm ◽  
Additive Part ◽  
Nano Cellulose ◽  
Potential Food

Solid-State Fermented Flaxseed Oil Cake of Improved Antioxidant Capacity as Potential Food Additive

2016 ◽  
Vol 41 (2) ◽  
pp. e12855 ◽  
Author(s):  
Bożena Stodolak ◽  
Anna Starzyńska-Janiszewska ◽  
Anna Wywrocka-Gurgul ◽  
Agnieszka Wikiera
Keyword(s):  
Solid State ◽  
Antioxidant Capacity ◽  
Flaxseed Oil ◽  
Food Additive ◽  
Potential Food

scholarly journals Review article: The effect of borax as a food additive on energy metabolism

2020 ◽  
Vol 23 (08) ◽  
Author(s):  
Yunita Satya Pratiwi ◽  
Irma Prasetyowati ◽  
Manik Nur Hidayati ◽  
Ruli Bahyu Antika ◽  
Lirista Dyah Ayu Oktafiani ◽  
...  
Keyword(s):  
Energy Metabolism ◽  
Review Article ◽  
Food Additive

Erythorbyl laurate as a potential food additive with multi-functionalities: Interfacial characteristics and antioxidant activity

2017 ◽  
Vol 215 ◽  
pp. 101-107 ◽  
Author(s):  
Kyung-Min Park ◽  
Min Joo Lee ◽  
Su-Kyung Jo ◽  
Seung Jun Choi ◽  
JaeHwan Lee ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Food Additive ◽  
Potential Food ◽  
Interfacial Characteristics

scholarly journals 5’-AMP-Activated Protein Kinase Regulates Goat Sperm Functions via Energy Metabolism In Vitro

2018 ◽  
Vol 47 (6) ◽  
pp. 2420-2431 ◽  
Author(s):  
Zhendong Zhu ◽  
Rongnan Li ◽  
Gongzhen Ma ◽  
Wenjing Bai ◽  
Xiaoteng Fan ◽  
...  
Keyword(s):  
Energy Metabolism ◽  
Mitochondrial Membrane ◽  
Acrosome Reaction ◽  
Membrane Integrity ◽  
Atp Content ◽  
Compound C ◽  
Ampk Phosphorylation ◽  
Amp Activated Protein Kinase ◽  
Sperm Functions

Background/Aims: ATP is essential for mammalian sperm to survive and maintain fertilizing capacity. AMP-activated protein kinase (AMPK) is a sensor of cellular energy status. The aims of the present study were to explore the localization of AMPK in goat sperm and to investigate whether and how AMPK regulates sperm functions in vitro. Methods: Sperm were treated with AMPK modulators (AICAR, metformin and Compound C) during incubation. Sperm motility was assessed with a computer-assisted spermatozoa analysis system (CASA). Membrane integrity, acrosome reaction and mitochondrial membrane potentials were detected by SYBR-14/PI, FITC-PNA and JC-1 staining, respectively. And the lactate content, ATP content, AMPK activity, activity of pyruvate kinase (PK) and lactate dehydrogenase (LDH) were also measured with the commercial assay kits. Immunofluorescence staining was used to analyze the distribution of PK, LDH, AMPK and phospho-Thr172-AMPK in sperm. The role of AMPK was further studied during induction of capacitation and acrosome reaction. Results: We found that AMPKα was localized in the entire acrosomal region, the midpiece and the flagellum, while the phospho-Thr172-AMPK was distributed in the head, the midpiece and flagellum. Activation of AMPK by AICAR and metformin significantly improved sperm motility, membrane integrity and acrosome reaction, largely maintained sperm mitochondrial membrane potentials, lactate content and ATP content, and enhanced the activity of AMPK, PK and LDH, whereas inhibition by Compound C triggered the converse effects. Moreover, PK was localized in the acrosomal area and the midpiece, while LDH was distributed in the tail. Induction of capacitation and acrosome reaction led to AMPK phosphorylation. AMPK phosphorylation regulated the activity of energetic enzymes. Conclusion: This study for the first time provides evidence that AMPK governs goat sperm functions through energy metabolism in vitro. This finding will help to improve assisted reproductive techniques in goats and the other species.

Safety evaluation studies of SGF gum—a potential food additive from the seed of Sesbania cannabina

1988 ◽  
Vol 26 (11-12) ◽  
pp. 935-946 ◽  
Author(s):  
Li Xili ◽  
Xu Eryi ◽  
Xu Gencheng ◽  
Shang Reiming ◽  
Wang Yuengming ◽  
...  
Keyword(s):  
Evaluation Studies ◽  
Safety Evaluation ◽  
Food Additive ◽  
Sesbania Cannabina ◽  
Potential Food

Erythorbyl laurate as a potential food additive with multi-functionalities: Antibacterial activity and mode of action

Food Control ◽  
2018 ◽  
Vol 86 ◽  
pp. 138-145 ◽  
Author(s):  
Kyung-Min Park ◽  
Su-Kyung Jo ◽  
Hyunjong Yu ◽  
Jun-Young Park ◽  
Seung Jun Choi ◽  
...  
Keyword(s):  
Antibacterial Activity ◽  
Mode Of Action ◽  
Food Additive ◽  
Potential Food
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