scholarly journals Chemical characterization and biological activities of two varieties of xoconostle fruits Opuntia joconostle F.A.C. Weber ex Diguet and Opuntia matudae Scheinvar

2019 ◽  
Vol 10 (6) ◽  
pp. 3181-3187
Author(s):  
Natalia Moraleja Garcia-Saavedra ◽  
Lillian Barros ◽  
Filipa S. Reis ◽  
Custódio Lobo Roriz ◽  
Maria José Alves ◽  
...  
Keyword(s):  
Biological Activities ◽  
Chemical Characterization ◽  
Good Source

Xoconostle fruits are a good source of healthy compounds.

scholarly journals Chemical Characterization and Biological Activities of Essential Oil Obtained from Mint Timija Cultivated under Mineral and Biological Fertilizers

2017 ◽  
Vol 2017 ◽  
pp. 1-7 ◽  
Author(s):  
Ayoub Kasrati ◽  
Chaima Alaoui Jamali ◽  
Robert Spooner-Hart ◽  
Laurent Legendre ◽  
David Leach ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Arbuscular Mycorrhizae ◽  
Biological Activities ◽  
Chemical Characterization ◽  
Mineral Fertilizer ◽  
Agronomic Practices ◽  
Significant Difference ◽  
Vesicular Arbuscular ◽  
Promising Solution ◽  
Biological Fertilizer

Cultivation of mint timija (Mentha suaveolens subsp. timija (Briq.) Harley) constitutes a promising solution to the conservation and sustainable utilization of this Moroccan endemic and threatened species. Optimized agronomic practices require mineral and/or biological fertilizer applications. The aim of this study was to determine the effects of application of a complete (N, P, and K) mineral fertilizer and vesicular arbuscular mycorrhizae (VAM) inoculation on the composition, antioxidant, and insecticidal properties of mint timija essential oils (EOs). The GC-MS analyses identified 27 components representing more than 99.9% of the total oils. Menthone (40.7–49.3%), pulegone (31.3–36.5%), and isomenthone (2.5–4.4%) were found to be the main constituents. Cultivation of mint timija with mineral fertilizer and VAM inoculation induced an increase in menthone content and a parallel decrease of pulegone. Both treatments enhanced the antioxidant activity of the investigated EOs in all assays (IC50 ranged from 2.34 ± 0.03 mg/mL to 6.82 ± 0.25 mg/mL), while no significant difference in the toxicities of these oils against Tribolium confusum du Val. has been observed. Overall, we conclude that cultivation using complete mineral fertilizer and VAM inoculation could be useful in modulating the chemical composition and enhancing the antioxidant activity of the EO of this endemic Moroccan species.

A novel Synthesis, Chemical Characterization and Biological Activities of Metal-Leather Protein Hydrolysate Chelates

2021 ◽  
Author(s):  
Rania Jacob ◽  
Hazem Hassan ◽  
Adel Afify ◽  
Gamal Gabr
Keyword(s):  
Melting Point ◽  
Protein Hydrolysate ◽  
Biological Activities ◽  
Chemical Characterization ◽  
Antibacterial Activities ◽  
Biochemical Properties ◽  
Mineral Salts ◽  
Mineral Absorption ◽  
E Coli ◽  
Leather Processing

Abstract Leather industries covers a wide chain of production and indirectly contributes to the economic flow. The different stages used in leather processing led to produce huge solid waste volumes. Because of the great effectiveness of amino acids as naturally chelates for minerals, the present study was carried out to recycling leather waste into its protein hydrolysate by CaO hydrolysis. The Leather protein hydrolysates (LPHs) was used to prepare metal-leather protein hydrolysate chelates (Cu2+-, Zn2+-& Fe2+-LPHCs) and some of their physical properties (i.e. λ-max, FTIR spectra, color, melting point) and biochemical properties as its antibacterial activity, as well as using as micronutrient elements for plant were evaluated. Results showed that the Cu2+-LPHC gave the highest value of melting point and λ-max than other chelates. All chelates shifted the vibration bands toward a higher frequency than LPH/CaO. Metal-leather protein hydrolysate (M-LPHCs) had antibacterial activities against E. coli, B. cereus and Micrococcus spp. mostly with Zn-LPHC and Fe-LPHC. These complexes also increased the growth characteristics and mineral absorption of spinach plants in hydroponic nutrient solution than that of mineral salts (CuSO4, ZnSO4 and FeSO4). Finally, the study concluded that M-LPHCs can be used as antimicrobial agent, micronutrients for plant and support the minerals bioavailability in animals.

scholarly journals Parallelism of Chemicostructural Properties between Filgrastim Originator and Three of Its Biosimilar Drugs

2019 ◽  
Vol 2019 ◽  
pp. 1-15 ◽  
Author(s):  
Alessandra Gianoncelli ◽  
Michela Bertuzzi ◽  
Michela Guarienti ◽  
Sara Vezzoli ◽  
Sara Anna Bonini ◽  
...  
Keyword(s):  
Biological Activity ◽  
Reference Product ◽  
Biological Activities ◽  
Chemical Characterization ◽  
Structural Similarity ◽  
Functional Assay ◽  
Biological Drugs ◽  
Reference Drug ◽  
Rp Hplc

The approval and granting of marketing authorization for a putative biosimilar is based on strong comparability studies with its biological reference product. This is due to the complexity of the structure and nature of the manufacturing process of biological drugs. Hence, a rigorous analytical workflow for chemical characterization and clinical trials to evaluate the efficacy and safety is required to demonstrate their high similarities to the reference drug. This work is focused on the comparison of the originator of filgrastim with three of its biosimilars by evaluating their structural similarity and biological activity. Qualiquantitative analyses were performed by MALDI-TOF/TOF-MS and RP-HPLC-UV. An innovative functional assay using zebrafish as the animal model was developed to evaluate the biological activities of the drugs. The different analyses performed in this study highlighted the structural similarity of biosimilar drugs and their originator. This result was further confirmed by a similar in vivo biological activity.

scholarly journals Identification of a Proanthocyanidin from Litchi Chinensis Sonn. Root with Anti-Tyrosinase and Antioxidant Activity

Biomolecules ◽  
2020 ◽  
Vol 10 (9) ◽  
pp. 1347
Author(s):  
Matthew Saive ◽  
Manon Genva ◽  
Thibaut Istasse ◽  
Michel Frederich ◽  
Chloé Maes ◽  
...  
Keyword(s):  
Antioxidant Activities ◽  
Biological Activities ◽  
Chemical Characterization ◽  
2D Nmr ◽  
Ethnobotanical Study ◽  
Traditional Use ◽  
Litchi Chinensis ◽  
Isolated Compound ◽  
First Time

This work follows an ethnobotanical study that took place in the island of Mayotte (France), which pointed out the potential properties of Litchi chinensis Sonn. roots when used to enhance skin health and appearance. Through in vitro testing of a crude methanolic extract, high anti-tyrosinase (skin whitening effect) and antioxidant activities (skin soothing effect) could be measured. HPLC successive bio-guided fractionation steps allowed the purification of one of the compounds responsible for the biological activities. The isolated compound was characterized by UV, IR, MS and 2D-NMR, revealing, for the first time in Litchi chinensis Sonn. roots, an A-type proanthocyanidin and thus revealing a consensus among the traditional use shown by the ethnobotanical study, in vitro biological activities and chemical characterization.

scholarly journals Chemical Composition and Insecticide Activity of Essential Oil of Mesosphaerum suaveolens Against Nauphoeta cinerea

2020 ◽  
Vol 8 (2) ◽  
pp. 352
Author(s):  
José Weverton Almeida Bezerra ◽  
Francisco Alves Grangeiro Neto ◽  
Jacques Tavares Pereira Filho ◽  
Adrielle Rodrigues Costa ◽  
Arycelle Alves de Oliveira ◽  
...  
Keyword(s):  
Essential Oil ◽  
Biological Activities ◽  
Chemical Constituents ◽  
Chemical Characterization ◽  
Positive Control ◽  
Plant Metabolites ◽  
Secondary Plant Metabolites ◽  
Nauphoeta Cinerea ◽  
Insecticide Activity ◽  
Insecticidal Action

Essential oils are compounds produced by secondary plant metabolites and are found in leaf trichomes, moreover, they are characteristic because they present strong odors and present biological activities. Thus, the objective of this work was to evaluate the insecticidal action of Mesosphaerum suaveolens essential oil against nymphs of Nauphoeta cinerea as well as to characterize the chemical constituents present in it. The EO was extracted by means of hydrodistillation and its chemical characterization was done by Gas Chromatography coupled to Mass Spectrometry (GC/MS). For the biological assay against cockroaches, nymphs of 20 days old were selected for which they were submitted to different concentrations (50 - 1000 μg/mL oil per air) and mortality was evaluated over 48 hours of EO exposure. As a positive control, ethanol (C2H6O) was used. Have been identified 44 compounds in EO, with β-Caryophyllene (18.57%), sabinene (15.94%) and spatulenol (11.09%) being the major compounds of EO. This showed no activity against the nymphs at any of the concentrations, whereas the positive control caused mortality at all concentrations tested. Thus, the essential oil of M. suaveolens does not present insecticidal properties in low concentrations against the cockroach.

scholarly journals General Characteristics, Phytochemistry and Pharmacognosy of Lippia sidoides

2015 ◽  
Vol 10 (11) ◽  
pp. 1934578X1501001 ◽  
Author(s):  
Luiz Gustavo de L. Guimarães ◽  
Maria Laura M. da Silva ◽  
Paula Campos J. Reis ◽  
Maria Tereza R. Costa ◽  
Lívia L. Alves
Keyword(s):  
Essential Oil ◽  
Traditional Medicine ◽  
Biological Activities ◽  
Chemical Characterization ◽  
Northeastern Brazil ◽  
Lippia Sidoides ◽  
Aerial Parts ◽  
The Family ◽  
Cultivation Methods

Lippia sidoides Cham. is a plant that belongs to the family Verbenaceae and is commonly known as “alecrim-pimenta”. It was first found in northeastern Brazil, where it is extensively used in traditional medicine. Many studies have been made with the essential oil of L. sidoides, which has a high content of the isomeric compounds thymol and carvacrol. L. sidoides extracts, and particularly the essential oil extracted from its aerial parts, have shown many biological activities such as antifungal, antibacterial, and insecticidal. Given the great biological potentialities of L. sidoides and the amount of recent studies about this plant, the present study aimed to make a survey of its general attributes, cultivation methods, chemical characterization of its extracts and essential oil, as well as its different biological activities.

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