scholarly journals Synthesis, characterization and biological evaluation of new manganese metal carbonyl compounds that contain sulfur and selenium ligands as a promising new class of CORMs

2019 ◽  
Vol 48 (17) ◽  
pp. 5574-5584 ◽  
Author(s):  
André L. Amorim ◽  
Marcos M. Peterle ◽  
Ana Guerreiro ◽  
Daniel F. Coimbra ◽  
Renata S. Heying ◽  
...  
Keyword(s):  
Carbonyl Compounds ◽  
Heavy Atom ◽  
Metal Carbonyl ◽  
Biological Evaluation ◽  
New Class ◽  
Manganese Carbonyl ◽  
Potential Use

Three new manganese carbonyl compounds with heavy atom donors were synthesized and their potential use as photoCORMS was evaluated.

1,4-Diazepines: A Review on Synthesis, Reactions and Biological Significance

2019 ◽  
Vol 16 (5) ◽  
pp. 709-729 ◽  
Author(s):  
Muhammad A. Rashid ◽  
Aisha Ashraf ◽  
Sahibzada S. Rehman ◽  
Shaukat A. Shahid ◽  
Adeel Mahmood ◽  
...  
Keyword(s):  
Biological Activities ◽  
Biological Significance ◽  
Biological Evaluation ◽  
Wide Range ◽  
Pharmaceutical Industries ◽  
Biological Aspects ◽  
Synthetic Routes ◽  
Biological Attributes ◽  
Synthesis Reactions ◽  
Potential Use

Background:1,4-Diazepines are two nitrogen containing seven membered heterocyclic compounds and associated with a wide range of biological activities. Due to its medicinal importance, scientists are actively involved in the synthesis, reactions and biological evaluation of 1,4-diazepines since number of decades.Objective:The primary purpose of this review is to discuss the synthetic schemes and reactivity of 1,4- diazepines. This article also describes biological aspects of 1,4-diazepine derivatives, that can be usefully exploited for the pharmaceutical sector.Conclusion:This review summarizes the abundant literature on synthetic routes, chemical reactions and biological attributes of 1,4-diazepine derivatives. We concluded that 1,4-diazepines have significant importance due to their biological activities like antipsychotic, anxiolytic, anthelmintic, anticonvulsant, antibacterial, antifungal and anticancer. 1,4-diazepine derivatives with significant biological activities could be explored for potential use in the pharmaceutical industries.

scholarly journals Synthesis and Biological Evaluation of 2-aroyl-4-phenyl-5- hydroxybenzofurans as a New Class of Antitubulin Agents

2008 ◽  
Vol 4 (6) ◽  
pp. 558-564 ◽  
Author(s):  
Romeo Romagnoli ◽  
Pier Baraldi ◽  
Taradas Sarkar ◽  
Carlota Cara ◽  
Olga Lopez ◽  
...  
Keyword(s):  
Biological Evaluation ◽  
New Class ◽  
Synthesis And Biological Evaluation

scholarly journals Synthesis and biological evaluation of nimesulide based new class of triazole derivatives as potential PDE4B inhibitors against cancer cells

2013 ◽  
Vol 23 (24) ◽  
pp. 6721-6727 ◽  
Author(s):  
Jyoti Mareddy ◽  
Suresh Babu Nallapati ◽  
Jayasree Anireddy ◽  
Yumnam Priyadarshini Devi ◽  
Lakshmi Narasu Mangamoori ◽  
...  
Keyword(s):  
Cancer Cells ◽  
Biological Evaluation ◽  
Triazole Derivatives ◽  
New Class ◽  
Synthesis And Biological Evaluation

Study of the CO stretching frequencies and intensities in metal-carbonyl compounds

1982 ◽  
Vol 82 (1-2) ◽  
pp. 43-50 ◽  
Author(s):  
M. van Rentergem ◽  
E.G. Claeys ◽  
G.P. van der Kelen
Keyword(s):  
Carbonyl Compounds ◽  
Metal Carbonyl

scholarly journals Synthesis and biological evaluation of benzothiazin-4-ones: a possible new class of acetylcholinesterase inhibitors

2018 ◽  
Vol 34 (1) ◽  
pp. 196-202 ◽  
Author(s):  
Gabriele A. Berwaldt ◽  
Daniela P. Gouvêa ◽  
Daniel S. da Silva ◽  
Adriana M. das Neves ◽  
Mayara S. P. Soares ◽  
...  
Keyword(s):  
Acetylcholinesterase Inhibitors ◽  
Biological Evaluation ◽  
New Class ◽  
Synthesis And Biological Evaluation

scholarly journals Binuclear Rhenium and Manganese Carbonyl Compounds Containing Hetero-Mercaptanes

2012 ◽  
Vol 25 (1) ◽  
pp. 62-70 ◽  
Author(s):  
Md Anwarul Hoque ◽  
Md Arzu Miah ◽  
Md Nurul Abser ◽  
Abul K Azad ◽  
Kamrun N Khan ◽  
...  
Keyword(s):  
Ambient Temperature ◽  
Spectral Data ◽  
1H Nmr ◽  
Metal Atom ◽  
Carbonyl Compounds ◽  
Chemical Society ◽  
Mass Spectral Data ◽  
Heterocyclic Ligands ◽  
Mass Spectral ◽  
Manganese Carbonyl

Treatment of 2-Mercaptothiazoline, 2-Mercaptobenzimidazole, 2-Mercapto-1- methylimidazole with [M2(CO)10] (M = Re and Mn) at ambient temperature in presence of decarbonylating reagent Me3NO give the complexes [Mn2(?-?2-C3H4NS2)2(CO)6] (1), [Re2(?-?2-C3H4NS2)2(CO)6] (2), [Mn2(?-?2-C7H5SN2)2(CO)6] (3), [Re2(?-?2- C7H5SN2)2(CO)6] (4), [Re2(?-?2-C4H5N2S)2(CO)6] (5) and [Re2(?1-C4H5N2SH)(CO)9] (6) respectively. All the compounds have been characterized by IR, 1H NMR and mass spectral data. The heterocyclic ligands are expected to be coordinated to two or single metal atom through the nitrogen and sulfur atoms or via only sulfur atom.DOI: http://dx.doi.org/10.3329/jbcs.v25i1.11775 Journal of Bangladesh Chemical Society, Vol. 25(1), 62-70, 2012> 

scholarly journals The aphid BCR4 structure and activity uncover a new defensin peptide superfamily

2021 ◽  
Author(s):  
Karine Loth ◽  
Nicolas Parisot ◽  
Francoise Paquet ◽  
Catherine Sivignon ◽  
Isabelle Rahioui ◽  
...  
Keyword(s):  
Acyrthosiphon Pisum ◽  
3D Structure ◽  
Pea Aphid ◽  
Symbiotic Bacteria ◽  
Structural Class ◽  
New Class ◽  
Agricultural Plants ◽  
Nymphal Growth ◽  
Structure And Activity ◽  
Potential Use

Aphids (Hemiptera: Aphidoidea) are among the most injuring insects for agricultural plants and their management is a great challenge in agronomical research. A new class of proteins, called Bacteriocyte-specific Cysteine-Rich (BCR), provides an alternative to chemical insecticides for pest control. BCRs have been initially identified in the pea aphid Acyrthosiphon pisum. They are small disulfide bond-rich proteins expressed exclusively in aphid bacteriocytes, the insect derived cells that host intracellular symbiotic bacteria. Here, we show that one out of the A. pisum BCRs, BCR4, displays an outstanding insecticidal activity against the pea aphid, impairing insect survival and nymphal growth, providing evidence for its potential use as a new biopesticides. Our comparative genomics and phylogenetic analysis indicate that BCRs seem restricted to the aphid lineage. The 3D structure of the BCR4 reveals that this peptide belongs to a yet unknown structural class of peptides and defines a new superfamily of defensins.

Sign in / Sign up

Export Citation Format

Share Document