scholarly journals Cobalt pincer complexes for catalytic reduction of nitriles to primary amines

2019 ◽  
Vol 9 (8) ◽  
pp. 1779-1783 ◽  
Author(s):  
Jacob Schneekönig ◽  
Bianca Tannert ◽  
Helen Hornke ◽  
Matthias Beller ◽  
Kathrin Junge
Keyword(s):  
Catalytic Reduction ◽  
Primary Amines ◽  
Pincer Complexes ◽  
Mild Conditions ◽  
Type Complex ◽  
High Yields ◽  
Hydrogenation Of Nitriles

An efficient cobalt pincer type complex catalyzes the hydrogenation of nitriles to amines under mild conditions with high yields.

A New Supported Rhodium Catalyst for Selective Hydrogenation of Nitriles to Primary Amines

2007 ◽  
Vol 72 (4) ◽  
pp. 468-474 ◽  
Author(s):  
Peter T. Witte
Keyword(s):  
Selective Hydrogenation ◽  
High Selectivity ◽  
Rhodium Catalyst ◽  
Primary Amines ◽  
Mild Conditions ◽  
Pharmaceutical Applications ◽  
Strong Acids ◽  
Hydrogenation Of Nitriles ◽  
Supported Rhodium Catalyst

Nitriles are converted to primary amines with high selectivity using a newly developed alumina-supported rhodium catalyst. The high selectivity is obtained without any additives, which are often used to prevent the formation of higher amines. The catalyst is active under mild conditions in various solvents, which makes it specifically suitable for use in pharmaceutical applications or for other substrates that can react with additives like strong acids or bases.

Direct catalytic synthesis of β-(C3)-substituted pyrroles: a complementary addition to the Paal–Knorr reaction

2021 ◽  
Vol 57 (2) ◽  
pp. 251-254
Author(s):  
Amol Prakash Pawar ◽  
Jyothi Yadav ◽  
Nisar Ahmad Mir ◽  
Eldhose Iype ◽  
Krishnan Rangan ◽  
...  
Keyword(s):  
Dft Calculations ◽  
Catalytic Synthesis ◽  
Primary Amines ◽  
Multicomponent Synthesis ◽  
Mild Conditions ◽  
Substituted Pyrroles ◽  
High Yields

Direct catalytic multicomponent synthesis of β-(C3)-substituted pyrroles is developed with good to high yields, using aqueous succinaldehyde, primary amines, and isatins under mild conditions. An access to the β-substituted free NH-pyrrole is the main focus of the work along with DFT-calculations.

Low-Pressure Hydrogenation of Nitriles to Primary Amines Catalyzed by Ruthenium Pincer Complexes. Scope and mechanism

ChemCatChem ◽  
2017 ◽  
Vol 9 (4) ◽  
pp. 559-563 ◽  
Author(s):  
Arup Mukherjee ◽  
Dipankar Srimani ◽  
Yehoshoa Ben-David ◽  
David Milstein
Keyword(s):  
Low Pressure ◽  
Primary Amines ◽  
Pincer Complexes ◽  
Hydrogenation Of Nitriles

scholarly journals Efficient and selective hydrogenation of amides to alcohols and amines using a well-defined manganese–PNN pincer complex

2017 ◽  
Vol 8 (5) ◽  
pp. 3576-3585 ◽  
Author(s):  
Veronica Papa ◽  
Jose R. Cabrero-Antonino ◽  
Elisabetta Alberico ◽  
Anke Spanneberg ◽  
Kathrin Junge ◽  
...  
Keyword(s):  
Selective Hydrogenation ◽  
Active Catalyst ◽  
Pincer Complexes ◽  
Mild Conditions ◽  
Pincer Complex ◽  
Wide Range ◽  
High Yields

Novel manganese NNP and PNP pincer complexes have been synthesized. The active catalyst allows the efficient hydrogenation of a wide range of amides under relatively mild conditions to afford alcohols and amines in high yields.

Selective catalytic hydrogenation of nitriles to primary amines using iron pincer complexes

2016 ◽  
Vol 6 (13) ◽  
pp. 4768-4772 ◽  
Author(s):  
S. Lange ◽  
S. Elangovan ◽  
C. Cordes ◽  
A. Spannenberg ◽  
H. Jiao ◽  
...  
Keyword(s):  
Catalytic Hydrogenation ◽  
Primary Amines ◽  
Pincer Complexes ◽  
Pincer Complex ◽  
Hydrogenation Of Nitriles

The selective catalytic hydrogenation of nitriles to primary amines with the well-defined Fe(PNPCy) pincer complex 2 is reported.

scholarly journals Quasi Pd1Ni single-atom surface alloy catalyst enables hydrogenation of nitriles to secondary amines

2019 ◽  
Vol 10 (1) ◽  
Author(s):  
Hengwei Wang ◽  
Qiquan Luo ◽  
Wei Liu ◽  
Yue Lin ◽  
Qiaoqiao Guan ◽  
...  
Keyword(s):  
Building Blocks ◽  
Surface Alloy ◽  
Secondary Amines ◽  
Single Atom ◽  
Redox Potentials ◽  
Practical Applications ◽  
Mild Conditions ◽  
Metal Selectivity ◽  
High Yields ◽  
Hydrogenation Of Nitriles

Abstract Hydrogenation of nitriles represents as an atom-economic route to synthesize amines, crucial building blocks in fine chemicals. However, high redox potentials of nitriles render this approach to produce a mixture of amines, imines and low-value hydrogenolysis byproducts in general. Here we show that quasi atomic-dispersion of Pd within the outermost layer of Ni nanoparticles to form a Pd1Ni single-atom surface alloy structure maximizes the Pd utilization and breaks the strong metal-selectivity relations in benzonitrile hydrogenation, by prompting the yield of dibenzylamine drastically from ∼5 to 97% under mild conditions (80 °C; 0.6 MPa), and boosting an activity to about eight and four times higher than Pd and Pt standard catalysts, respectively. More importantly, the undesired carcinogenic toluene by-product is completely prohibited, rendering its practical applications, especially in pharmaceutical industry. Such strategy can be extended to a broad scope of nitriles with high yields of secondary amines under mild conditions.

Mild and selective hydrogenation of nitriles into primary amines over a supported Ni catalyst

2020 ◽  
Vol 44 (2) ◽  
pp. 549-555 ◽  
Author(s):  
Jianjian Wang ◽  
Qingjie Tang ◽  
Shiwei Jin ◽  
Yanxin Wang ◽  
Ziliang Yuan ◽  
...  
Keyword(s):  
High Activity ◽  
Selective Hydrogenation ◽  
Primary Amines ◽  
Ni Catalyst ◽  
Mild Conditions ◽  
Supported Ni Catalyst ◽  
Supported Ni ◽  
Hydrogenation Of Nitriles

The mesoporous Al2O3 supported Ni catalyst demonstrated a high activity and selectivity for the hydrogenation of nitriles into primary amines under the mild conditions (60–80 °C and 2.5 bar H2) with ammonia as the additive.

Acceptorless amine dehydrogenation and transamination using Pd-doped layered double hydroxides

2018 ◽  
Author(s):  
Diana Ainembabazi ◽  
Nan An ◽  
Jinesh Manayil ◽  
Kare Wilson ◽  
Adam Lee ◽  
...  
Keyword(s):  
Layered Double Hydroxides ◽  
Oxidation States ◽  
Secondary Amines ◽  
Primary Amines ◽  
Acid Dissolution ◽  
Oxidative Amination ◽  
Strong Function ◽  
Excellent Activity ◽  
High Yields ◽  
Double Hydroxides

<div> <p>The synthesis, characterization, and activity of Pd-doped layered double hydroxides (Pd-LDHs) for for acceptorless amine dehydrogenation is reported. These multifunctional catalysts comprise Brønsted basic and Lewis acidic surface sites that stabilize Pd species in 0, 2+, and 4+ oxidation states. Pd speciation and corresponding cataytic performance is a strong function of metal loading. Excellent activity is observed for the oxidative transamination of primary amines and acceptorless dehydrogenation of secondary amines to secondary imines using a low Pd loading (0.5 mol%), without the need for oxidants. N-heterocycles, such as indoline, 1,2,3,4-tetrahydroquinoline, and piperidine, are dehydrogenated to the corresponding aromatics with high yields. The relative yields of secondary imines are proportional to the calculated free energy of reaction, while yields for oxidative amination correlate with the electrophilicity of primary imine intermediates. Reversible amine dehydrogenation and imine hydrogenation determine the relative imine:amine selectivity. Poisoning tests evidence that Pd-LDHs operate heterogeneously, with negligible metal leaching; catalysts can be regenerated by acid dissolution and re-precipitation.</p> </div> <br>

scholarly journals Electrochemical multicomponent synthesis of 4-selanylpyrazoles under catalyst- and chemical-oxidant-free conditions

2021 ◽  
Author(s):  
Yan Wu ◽  
Jin-Yang Chen ◽  
Jing Ning ◽  
Xue Jiang ◽  
Jie Deng ◽  
...  
Keyword(s):  
Multicomponent Reaction ◽  
Raw Materials ◽  
Multicomponent Synthesis ◽  
Mild Conditions ◽  
Simple Protocol ◽  
High Yields

An electrochemical multicomponent reaction was established under catalyst-, chemical-oxidant-free and mild conditions, which provides an eco-friendly and simple protocol for constructing 4-selanylpyrazoles from easily available raw materials with high yields.

Efficient Copper-Catalysed Synthesis of Carbazoles by Double N-Arylation of Primary Amines with 2,2′-Dibromobiphenyl in the Presence of Air

Synlett ◽  
2021 ◽  
Author(s):  
Tran Quang Hung ◽  
Tuan Thanh Dang ◽  
Peter Langer ◽  
Ha Nam Do ◽  
Nguyen Minh Quan ◽  
...  
Keyword(s):  
Aromatic Amines ◽  
Aliphatic Amines ◽  
Primary Amines ◽  
Coupling Reactions ◽  
Carbazole Derivatives ◽  
High Yields

AbstractAn efficient Cu-catalyzed synthesis of carbazole derivatives is reported, which proceeds by double C–N coupling reactions of 2,2′-dibromobiphenyl and amines in the presence of air. The reaction is robust, proceeds in high yields, and tolerates a series of amines including neutral, electron-rich, electron-deficient aromatic amines and aliphatic amines.

Sign in / Sign up

Export Citation Format

Share Document