Simulation guided design of silver nanostructures for plasmon-enhanced fluorescence, singlet oxygen generation and SERS applications

2020 ◽  
Vol 22 (10) ◽  
pp. 5673-5687 ◽  
Author(s):  
Mohammad Tavakkoli Yaraki ◽  
Soroosh Daqiqeh Rezaei ◽  
Yen Nee Tan
Keyword(s):  
Optical Properties ◽  
Singlet Oxygen ◽  
Raman Laser ◽  
Laser Wavelength ◽  
Silver Nanostructures ◽  
Enhanced Fluorescence ◽  
Oxygen Generation ◽  
Singlet Oxygen Generation ◽  
Silver Nanocubes ◽  
Plasmon Enhanced Fluorescence

A simulation-guided design of silver nanocubes for MEF, ME-SOG and SERS applications based on the fluorophore/photosensitizer's optical properties and Raman laser wavelength.

Cubic POSS engineering of photosensitizer-doped semiconducting polymer nanoparticles for enhanced fluorescence imaging and amplified photodynamic therapy

2020 ◽  
Vol 11 (44) ◽  
pp. 7035-7041
Author(s):  
Biqing Bao ◽  
Xue Zhai ◽  
Tianqi Liu ◽  
Peng Su ◽  
Luyao Zhou ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Singlet Oxygen ◽  
Fluorescence Imaging ◽  
Polymer Nanoparticles ◽  
Enhanced Fluorescence ◽  
Semiconducting Polymer ◽  
Oxygen Generation ◽  
Singlet Oxygen Generation ◽  
Semiconducting Polymer Nanoparticles

PorPOSSC12 -doped semiconducting polymer nanoparticles with simultaneously enhanced fluorescence brightness and amplified singlet oxygen generation ability were designed for imaging-guided photodynamic therapy.

Optical limiting and singlet oxygen generation properties of phosphorus triazatetrabenzcorroles

2015 ◽  
Vol 19 (01-03) ◽  
pp. 192-204 ◽  
Author(s):  
Colin Mkhize ◽  
Jonathan Britton ◽  
John Mack ◽  
Tebello Nyokong
Keyword(s):  
Optical Properties ◽  
Dipole Moment ◽  
Dft Calculations ◽  
Singlet Oxygen ◽  
Electronic Structures ◽  
Optical Limiting ◽  
Oxygen Generation ◽  
Singlet Oxygen Generation ◽  
Td Dft ◽  
Benzene Rings

Novel phosphorus triazatetrabenzcorrole (TBC) tetrasubstituted at the α- and β-positions of the peripheral fused benzene rings with t-butylphenoxy substituents have been prepared and characterized. The effect of the substituents on the electronic structures and optical properties is investigated with TD-DFT calculations and MCD spectroscopy. The optical limiting properties have been investigated to examine whether the lower symmetry that results from the direct pyrrole–pyrrole bond and hence the permanent dipole moment that is introduced result in higher safety thresholds, relative to the values that have been reported for phthalocyanines. The suitability of the compounds for singlet oxygen applications has also been examined.

Protoporphyrin IX Nanoparticle Carrier: Preparation, Optical Properties, and Singlet Oxygen Generation

Langmuir ◽  
2008 ◽  
Vol 24 (21) ◽  
pp. 12534-12538 ◽  
Author(s):  
Liane M. Rossi ◽  
Paulo R. Silva ◽  
Lucas L. R. Vono ◽  
Adjaci U. Fernandes ◽  
Dayane B. Tada ◽  
...  
Keyword(s):  
Optical Properties ◽  
Singlet Oxygen ◽  
Protoporphyrin Ix ◽  
Oxygen Generation ◽  
Singlet Oxygen Generation

scholarly journals Gold Nanostars-AIE Theranostic Nanodots with Enhanced Fluorescence and Photosensitization Towards Effective Image-Guided Photodynamic Therapy

2021 ◽  
Vol 13 (1) ◽  
Author(s):  
Mohammad Tavakkoli Yaraki ◽  
Min Wu ◽  
Eshu Middha ◽  
Wenbo Wu ◽  
Soroosh Daqiqeh Rezaei ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Singlet Oxygen ◽  
Enhancement Factor ◽  
Fluorescence Emission ◽  
Localized Surface Plasmon ◽  
Enhanced Fluorescence ◽  
Oxygen Generation ◽  
Image Guided ◽  
Singlet Oxygen Generation

AbstractDual-functional aggregation-induced photosensitizers (AIE-PSs) with singlet oxygen generation (SOG) ability and bright fluorescence in aggregated state have received much attention in image-guided photodynamic therapy (PDT). However, designing an AIE-PS with both high SOG and intense fluorescence via molecular design is still challenging. In this work, we report a new nanohybrid consisting of gold nanostar (AuNS) and AIE-PS dots with enhanced fluorescence and photosensitization for theranostic applications. The spectral overlap between the extinction of AuNS and fluorescence emission of AIE-PS dots (665 nm) is carefully selected using five different AuNSs with distinct localized surface plasmon (LSPR) peaks. Results show that all the AuNSs can enhance the 1O2 production of AIE-PS dots, among which the AuNS with LSPR peak at 585 nm exhibited the highest 1O2 enhancement factor of 15-fold with increased fluorescence brightness. To the best of our knowledge, this is the highest enhancement factor reported for the metal-enhanced singlet oxygen generation systems. The Au585@AIE-PS nanodots were applied for simultaneous fluorescence imaging and photodynamic ablation of HeLa cancer cells with strongly enhanced PDT efficiency in vitro. This study provides a better understanding of the metal-enhanced AIE-PS nanohybrid systems, opening up new avenue towards advanced image-guided PDT with greatly improved efficacy.

Design of Novel Photosensitizers and Controlled Singlet Oxygen Generation for Photodynamic Therapy

2021 ◽  
Author(s):  
Esra Tanrıverdi Eçik ◽  
Onur BULUT ◽  
Hasan Hüseyin Kazan ◽  
Elif Şenkuytu ◽  
Bunyemin Cosut
Keyword(s):  
Photodynamic Therapy ◽  
Cancer Treatment ◽  
Singlet Oxygen ◽  
Side Effect ◽  
Side Effect Profile ◽  
High Ability ◽  
Lower Side ◽  
Oxygen Generation ◽  
Singlet Oxygen Generation ◽  
Promising Strategy

Photodynamic therapy (PDT) is a promising strategy in cancer treatment with its relatively lower side effect profile. Undoubtedly, the key component of PDT is the photosensitizers with a high ability...

Achieving high singlet-oxygen generation by applying the heavy-atom effect to thermally activated delayed fluorescent materials

2021 ◽  
Author(s):  
Ya-Fang Xiao ◽  
Jia-Xiong Chen ◽  
Wen-Cheng Chen ◽  
Xiuli Zheng ◽  
Chen Cao ◽  
...  
Keyword(s):  
Singlet Oxygen ◽  
Heavy Atom ◽  
Synergetic Effect ◽  
Heavy Atom Effect ◽  
Oxygen Generation ◽  
Thermally Activated ◽  
Singlet Oxygen Generation ◽  
Fluorescent Materials ◽  
Atom Effect

Applying the heavy-atom effect to TADF photosensitizers achieves ultra-high 1O2 generation (ФΔ = 0.91) by the synergetic effect of small ΔEST and considerable SOC.

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