Strategic planning of proteins in ionic liquids: future solvents for the enhanced stability of proteins against multiple stresses

2019 ◽  
Vol 21 (42) ◽  
pp. 23269-23282 ◽  
Author(s):  
Awanish Kumar ◽  
Kavya Bhakuni ◽  
Pannuru Venkatesu
Keyword(s):  
Ionic Liquids ◽  
Strategic Planning ◽  
Organic Solvents ◽  
Biomedical Applications ◽  
Protein Stabilization ◽  
Multiple Stresses ◽  
Toxic Organic Solvents ◽  
Enhanced Stability

Ionic liquids (ILs) represent as solvents or co-solvents for protein stabilization and refolding. Thus, ILs are replacement to toxic organic solvents in chemical, biotechnology and biomedical applications.

scholarly journals Long-term protein packaging in cholinium-based ionic liquids: improved catalytic activity and enhanced stability of cytochrome c against multiple stresses

2017 ◽  
Vol 19 (20) ◽  
pp. 4900-4911 ◽  
Author(s):  
Meena Bisht ◽  
Dibyendu Mondal ◽  
Matheus M. Pereira ◽  
Mara G. Freire ◽  
P. Venkatesu ◽  
...  
Keyword(s):  
Enzyme Activity ◽  
Catalytic Activity ◽  
Ionic Liquids ◽  
Cytochrome C ◽  
Multiple Stresses ◽  
Improved Stability ◽  
Cyt C ◽  
Enhanced Stability

Cholinium-based ionic liquids are shown to be promising packaging media of Cyt c with >50 fold enhancement in the enzyme activity and improved stability against multiple stresses.

Electrogenerated NHCs in Organic Synthesis: Ionic Liquids vs Organic Solvents Effects

2021 ◽  
Author(s):  
Fabrizio Vetica ◽  
Martina Bortolami ◽  
Rita Petrucci ◽  
Daniele Rocco ◽  
Marta Feroci
Keyword(s):  
Ionic Liquids ◽  
Organic Synthesis ◽  
Organic Solvents

scholarly journals Membrane manufacture for peptide separation

2016 ◽  
Vol 18 (19) ◽  
pp. 5151-5159 ◽  
Author(s):  
DooLi Kim ◽  
Octavio R. Salazar ◽  
Suzana Pereina Nunes
Keyword(s):  
Ionic Liquids ◽  
Protein Separation ◽  
Biomedical Applications ◽  
Food Industry ◽  
Green Solvent ◽  
Seawater Desalination ◽  
Peptide Separation ◽  
Polysulfone Membranes

Polysulfone membranes are key tools in biomedical applications, such as hemodialysis and protein separation, in the food industry, and in seawater desalination. Ionic liquids are proposed as green solvent for membrane manufacture with tailored peptide selectivity.

Prediction and correlation of viscosity of binary mixtures of ionic liquids with organic solvents

2014 ◽  
Vol 197 ◽  
pp. 1-6 ◽  
Author(s):  
Divna M. Bajić ◽  
Slobodan P. Šerbanović ◽  
Emila M. Živković ◽  
Jovan Jovanović ◽  
Mirjana Lj. Kijevčanin
Keyword(s):  
Ionic Liquids ◽  
Binary Mixtures ◽  
Organic Solvents

Phase behavior of mixtures of ionic liquids and organic solvents

2010 ◽  
Vol 55 (2) ◽  
pp. 833-845 ◽  
Author(s):  
Jens Abildskov ◽  
Martin D. Ellegaard ◽  
John P. O’Connell
Keyword(s):  
Ionic Liquids ◽  
Phase Behavior ◽  
Organic Solvents

Ionic liquids or eutectic solvents? Identifying the best solvents for the extraction of astaxanthin and β-carotene from Phaffia rhodozyma yeast and preparation of biodegradable films

2021 ◽  
Author(s):  
Cassamo Mussagy ◽  
Valéria Ebinuma-Santos ◽  
Rondinelli Herculano ◽  
Joao A. P. Coutinho ◽  
Jorge F B Pereira ◽  
...  
Keyword(s):  
Ionic Liquids ◽  
Organic Solvents ◽  
Phaffia Rhodozyma ◽  
Biodegradable Films ◽  
Β Carotene

In order to replace conventional organic solvents by more benign equivalents such as ionic liquids or eutetic solvents, in this work we attempt to develop a simple and ecofriendly process...

Synthesis of organophosphorus compounds using ionic liquids

2018 ◽  
Vol 34 (5) ◽  
pp. 727-740 ◽  
Author(s):  
Lavinia Macarie ◽  
Nicoleta Plesu ◽  
Smaranda Iliescu ◽  
Gheorghe Ilia
Keyword(s):  
Ionic Liquids ◽  
Organophosphorus Compounds ◽  
Inorganic Compounds ◽  
Green Solvents ◽  
High Solubility ◽  
Chemical Reagents ◽  
Reaction Media ◽  
Organophosphorus Chemistry ◽  
Synthesis Reactions ◽  
Toxic Organic Solvents

Abstract Organophosphorus chemistry was developed in the last decade by promoting the synthesis reactions using ionic liquids either as solvent or catalyst. Ionic liquids (ILs), the so-called “green solvents”, have gained interest in the synthesis of organophosphorus compounds as alternatives to flammable and toxic organic solvents and catalysts. ILs have beneficial properties because they provide high solubility for many organic and inorganic compounds or metal complexes, have no vapor pressure, and are reusable. Also, in some cases, they can enhance the reactivity of chemical reagents. In this review, we aimed at showing the synthesis of different organophosphorus compounds under green and mild conditions using ILs as reaction media or catalysts, according to a trend developed in the last years. A novel trend is to perform these syntheses under microwave irradiation conditions together with ILs as solvents and catalysts.

scholarly journals Promising biocompatible hydrogels of crosslinked polyelectrolytes for biomedical applications

2017 ◽  
Vol 3 (2) ◽  
pp. 695-698
Author(s):  
Andreas Brietzke ◽  
Christian von der Ehe ◽  
Sabine Illner ◽  
Claudia Matschegewski ◽  
Niels Grabow ◽  
...  
Keyword(s):  
Aqueous Solution ◽  
Ionic Liquids ◽  
Cell Viability ◽  
Biomedical Applications ◽  
High Potential ◽  
Cell Viability Assay ◽  
Mouse Fibroblasts ◽  
Viability Assay ◽  
Intelligent Implant ◽  
L929 Mouse

AbstractFor the development of intelligent implant systems hydrogels (HG) from crosslinked ionic liquids feature a high potential to be utilised as a drug depot. Biocompatibility of the HGs is one key prerequisite for biomedical applications. HGs were polymerised from a variety of different ionic monomers based on methacrylate, methacrylamide, styrene or vinyl imidazolium derivatives in aqueous solution. N,N'-methylenebisacrylamide was used as crosslinker. CellQuanti-Blue™ Cell Viability Assay Kit was implemented to proof viability of L929 mouse fibroblasts. The predominant part of the HG eluates generated only a marginal reduction of less than 15% cell viability at 100% eluate concentration. This underlines the excellent suitability of these HGs for biomedical applications and revealed some promising candidates for the development of drug depots for implants.

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