Elongated magnetic nanoparticles with high-aspect ratio: a nuclear relaxation and specific absorption rate investigation

2019 ◽  
Vol 21 (34) ◽  
pp. 18741-18752
Author(s):  
Matteo Avolio ◽  
Helena Gavilán ◽  
Eva Mazario ◽  
Francesca Brero ◽  
Paolo Arosio ◽  
...  
Keyword(s):  
Magnetic Nanoparticles ◽  
Aspect Ratio ◽  
Physical Properties ◽  
High Aspect Ratio ◽  
Biomedical Applications ◽  
Absorption Rate ◽  
Specific Absorption Rate ◽  
Nuclear Relaxation ◽  
Specific Absorption ◽  
Elongated Nanoparticles

High aspect-ratio elongated nanoparticles with suitable porosity present partially controlled chemico-physical properties to obtain good heating/contrast efficiency for biomedical applications.

Effect of Bi Ions on the Hyperthermia Properties of Hyaluronic Acid-Coated La1−xSrxMnO3 Nanoparticles

NANO ◽  
2020 ◽  
Vol 15 (01) ◽  
pp. 2050015
Author(s):  
Lihan zheng ◽  
Yuanwei Chen ◽  
Ying Wang ◽  
Peng Wang ◽  
Tao Wang
Keyword(s):  
Hyaluronic Acid ◽  
Magnetic Nanoparticles ◽  
Curie Temperature ◽  
Absorption Rate ◽  
Specific Absorption Rate ◽  
Heating Temperature ◽  
Particle Diameter ◽  
High Energy ◽  
Average Particle ◽  
Specific Absorption

Self-regulating temperature hyperthermia based on magnetic fluid with low Curie temperature is a moderately effective method for cancer treatment. The improvement of the properties of magnetic fluids is the key for application of this method. In this paper, Bi-doped LSMO magnetic nanoparticles were synthesized using a simple sol–gel method and coated by hyaluronic acid through high energy ball milling for their possible application in self-regulating temperature hyperthermia. The crystal structure, morphology, basic magnetic properties and heating properties of these nanoparticles in a high frequency magnetic field were investigated. It was found that the hyaluronic acid-coated La[Formula: see text]Sr[Formula: see text]Bi[Formula: see text]MnO3 magnetic nanoparticles, with an average particle diameter of [Formula: see text]100[Formula: see text]nm and a Curie temperature of 48∘C, possess outstanding induction heating properties. The saturation heating temperature, specific absorption rate and effective specific absorption rate are 48∘C, 117[Formula: see text]W/g and 0.27[Formula: see text]W/g[Formula: see text]kHz[Formula: see text](kA/m2), respectively.

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