Revealing the critical role of template functional group ordering in the template-directed crystallization of pyrazinamide

CrystEngComm ◽  
2019 ◽  
Vol 21 (42) ◽  
pp. 6382-6389 ◽  
Author(s):  
Keke Zhang ◽  
Shijie Xu ◽  
Junbo Gong ◽  
Weiwei Tang
Keyword(s):  
Functional Groups ◽  
Functional Group ◽  
Critical Role ◽  
Directed Crystallization ◽  
Specific Orientation

The nucleation of γ form pyrazinamide can be directed by the ordering and specific orientation of the template functional groups.

scholarly journals Natural Products Containing ‘Rare’ Organophosphorus Functional Groups

Molecules ◽  
2019 ◽  
Vol 24 (5) ◽  
pp. 866 ◽  
Author(s):  
Janusz Petkowski ◽  
William Bains ◽  
Sara Seager
Keyword(s):  
Amino Acids ◽  
Natural Products ◽  
Functional Groups ◽  
Functional Group ◽  
Organophosphorus Compounds ◽  
Living Cells ◽  
Unusual Amino Acids ◽  
Biological Source ◽  
Technological Limitations

Phosphorous-containing molecules are essential constituents of all living cells. While the phosphate functional group is very common in small molecule natural products, nucleic acids, and as chemical modification in protein and peptides, phosphorous can form P–N (phosphoramidate), P–S (phosphorothioate), and P–C (e.g., phosphonate and phosphinate) linkages. While rare, these moieties play critical roles in many processes and in all forms of life. In this review we thoroughly categorize P–N, P–S, and P–C natural organophosphorus compounds. Information on biological source, biological activity, and biosynthesis is included, if known. This review also summarizes the role of phosphorylation on unusual amino acids in proteins (N- and S-phosphorylation) and reviews the natural phosphorothioate (P–S) and phosphoramidate (P–N) modifications of DNA and nucleotides with an emphasis on their role in the metabolism of the cell. We challenge the commonly held notion that nonphosphate organophosphorus functional groups are an oddity of biochemistry, with no central role in the metabolism of the cell. We postulate that the extent of utilization of some phosphorus groups by life, especially those containing P–N bonds, is likely severely underestimated and has been largely overlooked, mainly due to the technological limitations in their detection and analysis.

scholarly journals Critical Role of Functional Groups Containing N, S, and O on Graphene Surface for Stable and Fast Charging Li‐S Batteries

Small ◽  
2021 ◽  
pp. 2007242
Author(s):  
Jinhua Sun ◽  
Jang‐Yeon Hwang ◽  
Piotr Jankowski ◽  
Linhong Xiao ◽  
Jaime S. Sanchez ◽  
...  
Keyword(s):  
Functional Groups ◽  
Critical Role ◽  
Graphene Surface ◽  
Fast Charging

Steel Industry Wastes Treatment in Buffer Ponds

1987 ◽  
Vol 19 (12) ◽  
pp. 363-364
Author(s):  
V. M. Bagnyuk
Keyword(s):  
Functional Groups ◽  
Steel Industry ◽  
Functional Group ◽  
Ecological Factors ◽  
The Self ◽  
Biogenic Elements ◽  
Limiting Factor ◽  
High Turbidity

The bioprocesses of steel industry wastes self-purification in buffer ponds have been studied. The representatives of 6-7 divisions of microalgae and many functional groups of bacteria have been found in the ponds. The important role of a new functional group, the “lytic” microorganisms, in the regulation of microecosystems and in bacterial self-purification has been established. It was found that the activity of self-purification bioprocesses in the buffer ponds studied depends on a variety of ecological factors. The main limiting factor has been shown to be the high turbidity of water, and its deficit of dissolved phosphates and oxygen. To accelerate the self-purification of steel industry wastes in buffer ponds the concentration of organic and mineral forms of the main biogenic elements (C,N,P) should be regulated. Water clarification and aeration were recommended and effectively used.

scholarly journals Complexations of Divalent Metallic Ions with Fulvic Acids

2018 ◽  
Vol 43 (1) ◽  
pp. 54
Author(s):  
Denise De Oliveira Vaz ◽  
Andreia Neves Fernandes ◽  
Bruno Szpoganicz
Keyword(s):  
Functional Groups ◽  
Functional Group ◽  
Fulvic Acids ◽  
Aquatic Environments ◽  
Metallic Ions ◽  
Divalent Ions ◽  
Proton Dissociation ◽  
Bivalent Ions ◽  
Suwannee River Fulvic Acid

In this work, the interactions of the functional groups of fulvic acids with copper, cadmium and zinc bivalent ions was investigated by potentiometry. The BEST7 software was employed to investigate the interactions of the functional groups. The software SPE and SPEPLOT were used to generate and to plot the species diagrams. It was used the Suwannee River fulvic acid (SRFA) of the IHSS (International Humic Substances Society) to illustrate the process. The values of the proton dissociation and complexation constants with the divalent ions for each functional group were calculated and their values were very close tothose previously published. The functional group present in the highest quantity in the complexes was cathecol, and it complexed with all the divalent ions, although to a greater extent with Cu(II). According to the results obtained by potentiometry, the reactivity series for the divalent ions and the SRFA is: Cu(II) >> Cd(II) > Zn(II). Thus, the method employed could be useful to estimate the role of fulvic acids in the transport of metals in the aquatic environments.

The Critical Role of Oxygen-Containing Functional Groups in the Etching Behavior of Activators to Carbon Materials

2021 ◽  
Vol 9 (4) ◽  
pp. 1646-1655
Author(s):  
Shaohua Zhang ◽  
Xiangyang Li ◽  
Jiangqi Zhou ◽  
Lijie Li ◽  
Lixia Bao ◽  
...  
Keyword(s):  
Functional Groups ◽  
Carbon Materials ◽  
Critical Role ◽  
Etching Behavior

The Role of the SLP in Autism Spectrum Disorder Screening and Assessment

2008 ◽  
Vol 15 (2) ◽  
pp. 50-59 ◽  
Author(s):  
Amy Philofsky
Keyword(s):  
Language Development ◽  
Critical Role ◽  
Children With Autism ◽  
Autism Spectrum ◽  
Children With Asd ◽  
Prevalence Estimates ◽  
Notable Increase ◽  
Screening Assessment ◽  
Critical Components

AbstractRecent prevalence estimates for autism have been alarming as a function of the notable increase. Speech-language pathologists play a critical role in screening, assessment and intervention for children with autism. This article reviews signs that may be indicative of autism at different stages of language development, and discusses the importance of several psychometric properties—sensitivity and specificity—in utilizing screening measures for children with autism. Critical components of assessment for children with autism are reviewed. This article concludes with examples of intervention targets for children with ASD at various levels of language development.

A critical role of iNOS-derived Nitric Oxide (NO) and progesterone in implantation

1998 ◽  
Vol 5 (1) ◽  
pp. 115A-115A
Author(s):  
K CHWALISZ ◽  
E WINTERHAGER ◽  
T THIENEL ◽  
R GARFIELD
Keyword(s):  
Nitric Oxide ◽  
Critical Role
Sign in / Sign up

Export Citation Format

Share Document