A multi-stimuli-responsive metallohydrogel applied in chiral recognition, adsorption of poisonous anions, and construction of various chiral metal–organic frameworks

2019 ◽  
Vol 55 (94) ◽  
pp. 14178-14181 ◽  
Author(s):  
Xuebin Xu ◽  
Jiannan Xiao ◽  
Meiying Liu ◽  
Zhiliang Liu
Keyword(s):  
Chiral Recognition ◽  
Metal Organic Frameworks ◽  
Stimuli Responsive ◽  
Metal Organic

A multi-stimuli-responsive chiral metallohydrogel applied to chiral recognition, adsorption of poisonous anions, and construction of various chiral metal–organic frameworks.

Chiral Recognition and Separation by Chirality-Enriched Metal-Organic Frameworks

2018 ◽  
Vol 57 (28) ◽  
pp. 8629-8633 ◽  
Author(s):  
Saikat Das ◽  
Shixian Xu ◽  
Teng Ben ◽  
Shilun Qiu
Keyword(s):  
Chiral Recognition ◽  
Metal Organic Frameworks ◽  
Metal Organic

Synthesis and therapeutic potential of stimuli-responsive metal-organic frameworks

2020 ◽  
pp. 127233
Author(s):  
Shahla Karimzadeh ◽  
Siamak Javanbakht ◽  
Behzad Baradaran ◽  
Mohammad-Ali Shahbazi ◽  
Mahmoud Hashemzaei ◽  
...  
Keyword(s):  
Therapeutic Potential ◽  
Metal Organic Frameworks ◽  
Stimuli Responsive ◽  
Metal Organic

scholarly journals Stimuli-responsive metal–organic frameworks gated by pillar[5]arene supramolecular switches

2015 ◽  
Vol 6 (3) ◽  
pp. 1640-1644 ◽  
Author(s):  
Li-Li Tan ◽  
Haiwei Li ◽  
Yu-Chen Qiu ◽  
Dai-Xiong Chen ◽  
Xin Wang ◽  
...  
Keyword(s):  
Metal Organic Frameworks ◽  
Stimuli Responsive ◽  
Triggered Release ◽  
Metal Organic ◽  
Hybrid Platform ◽  
First Time

Mechanized monodisperse nano metal–organic frameworks (NMOFs) gated by carboxylatopillar[5]arene (CP5) switches with bio-friendly pH-triggered release capabilities were constructed for the first time as a new stimuli-responsive theranostic hybrid platform.

Stimuli-responsive structural changes in metal–organic frameworks

2020 ◽  
Vol 56 (66) ◽  
pp. 9416-9432 ◽  
Author(s):  
Zhanning Liu ◽  
Lu Zhang ◽  
Daofeng Sun
Keyword(s):  
Structural Changes ◽  
Metal Organic Frameworks ◽  
Stimuli Responsive ◽  
Feature Article ◽  
Metal Organic ◽  
External Stimuli

This feature article mainly summarizes how the structure of MOFs changes under external stimuli.

Stimuli‐Responsive Luminescent Properties of Tetraphenylethene‐Based Strontium and Cobalt Metal–Organic Frameworks

2020 ◽  
Vol 132 (44) ◽  
pp. 19884-19889
Author(s):  
Xiaolei Guo ◽  
Nansong Zhu ◽  
Shi‐Ping Wang ◽  
Guanghua Li ◽  
Fu‐Quan Bai ◽  
...  
Keyword(s):  
Metal Organic Frameworks ◽  
Luminescent Properties ◽  
Cobalt Metal ◽  
Stimuli Responsive ◽  
Metal Organic

Progress of Stimuli-Responsive Nanoscale Metal Organic Frameworks as Controlled Drug Delivery Systems

2020 ◽  
Vol 17 ◽  
Author(s):  
Ailing Feng ◽  
Yanni Wang ◽  
Jinzi Ding ◽  
Rong Xu ◽  
Xiaodong Li
Keyword(s):  
Drug Delivery ◽  
Drug Delivery Systems ◽  
Metal Organic Framework ◽  
Metal Organic Frameworks ◽  
Controlled Drug Delivery ◽  
Delivery Systems ◽  
Stimuli Responsive ◽  
Direct Assembly ◽  
Metal Organic ◽  
Organic Framework

Background: Development of controlled drug delivery systems can improve the pharmacokinetic characteristics of drug molecules in the human body, thereby significantly improving the utilization rate of drugs and reducing toxicity and side effects caused by high concentrations of drugs, which can occur when delivery is not controlled. Metal organic frameworks are a new class of very promising crystalline microporous materials, especially when the size is reduced to the nanometer range. Metal organic frameworks exhibit large specific surface areas, tunable compositions, and easy functionalization. In recent years, increasing number of studies have reported the remarkable advances in multifunctional nanoscale metal organic frameworks in drug delivery. Objective: Review the latest research involving advances in stimuli-responsive nanoscale metal organic frameworks as drug delivery systems in controlled-release drugs. Discussion: We first introduce the two main strategies associated with nanoscale metal organic frameworks used in drug loading: direct assembly and post-encapsulation. We next focus on the latest discoveries of nanoscale metal organic framework-based stimulus response systems for drug delivery, including pH, magnetics, light, ion, temperature, and other stimuli, as well as multiple stimulus-responsive drug delivery systems. Finally, we discuss the challenges and future development directions of nanoscale metal organic framework-based controlled drug release.

Stimuli-Responsive DNA-Functionalized Metal-Organic Frameworks (MOFs)

2016 ◽  
Vol 29 (6) ◽  
pp. 1602782 ◽  
Author(s):  
Jason S. Kahn ◽  
Lina Freage ◽  
Natalie Enkin ◽  
Miguel Angel Aleman Garcia ◽  
Itamar Willner
Keyword(s):  
Metal Organic Frameworks ◽  
Stimuli Responsive ◽  
Metal Organic

Asymmetric Metal-Organic Frameworks with Double Helices for Enantioselective Recognition

CrystEngComm ◽  
2021 ◽  
Author(s):  
Yang Li ◽  
Shumei Chen ◽  
Zhong-Xuan Xu ◽  
Xin Wu ◽  
Huabin Zhang ◽  
...  
Keyword(s):  
Hydrogen Bonding ◽  
Chiral Recognition ◽  
Metal Organic Frameworks ◽  
Enantioselective Recognition ◽  
Double Helices ◽  
Recognition Ability ◽  
Metal Organic

A pair of homochiral metal-organic frameworks are elaborated by employing flexible enantiopure ligands. They possess interesting double helical chains and rich hydrogen-bonding environment, exhibiting excellent chiral recognition ability to carvone.

scholarly journals Metal-Organic Frameworks for Drug Delivery Applications

2021 ◽  
pp. 139-170
Author(s):  
Doaa Ahmed Ghareeb ◽  
Nessma Magdy Nasr
Keyword(s):  
Drug Delivery ◽  
Controlled Release ◽  
Drug Delivery Systems ◽  
Metal Organic Frameworks ◽  
Stimuli Responsive ◽  
Surface Areas ◽  
Wide Range ◽  
Metal Organic ◽  
Delivery Vehicles ◽  
Structural Aspects

Metal-organic frameworks (MOFs) are based on metals and organic linkers; they possess large surface areas, suitable pore size and shape, wide range of chemical composition, and functionalized pore surface, which enable them for possible applications as delivery vehicles for therapeutic agents. The challenges include not only the development of new solids but also continuous improvements in the formulation and processing of the materials, including modifying the morphology and shape of the frameworks to fit the proposed applications of drug delivery. This chapter discussed enormous MOF-based stimuli responsive drug delivery systems, and considerable achievements have been made as a new avenue for drug delivery, their structural aspects, their applications in the controlled release of the drugs, and future view for development of drug controlled release researches using MOFs. Among the properties that must be developed and approved are the materials' toxicology, stability, their reproducibility of manufacture of MOFs in body's liquid, and pharmacokinetics of drug-loaded MOFs.

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