Electrosynthesis of amino acids from biomass-derivable acids on titanium dioxide

2019 ◽  
Vol 55 (98) ◽  
pp. 14721-14724 ◽  
Author(s):  
Takashi Fukushima ◽  
Miho Yamauchi
Keyword(s):  
Amino Acids ◽  
Titanium Dioxide ◽  
Keto Acids ◽  
Earth Abundant

Amino acids were electrochemically synthesized from biomass-derivable α-keto acids and water with high faradaic efficiencies using safe and earth-abundant TiO2.

Photolysis of amino acids in sunlight in presence of the photosensitizer titanium dioxide

1953 ◽  
Vol 40 (16) ◽  
pp. 440-441 ◽  
Author(s):  
K. V. Giri ◽  
G. D. Kalyankar ◽  
C. S. Vaidyanathan
Keyword(s):  
Amino Acids ◽  
Titanium Dioxide

scholarly journals ω-Amino Acid:Pyruvate Transaminase from Alcaligenes denitrificans Y2k-2: a New Catalyst for Kinetic Resolution of β-Amino Acids and Amines

2004 ◽  
Vol 70 (4) ◽  
pp. 2529-2534 ◽  
Author(s):  
Hyungdon Yun ◽  
Seongyop Lim ◽  
Byung-Kwan Cho ◽  
Byung-Gee Kim
Keyword(s):  
Amino Acids ◽  
Kinetic Resolution ◽  
Specific Activity ◽  
Expression System ◽  
Enantiomeric Excess ◽  
Selective Enrichment ◽  
Alcaligenes Denitrificans ◽  
Keto Acids ◽  
Optically Pure ◽  
High Stereoselectivity

ABSTRACT Alcaligenes denitrificans Y2k-2 was obtained by selective enrichment followed by screening from soil samples, which showed ω-amino acid:pyruvate transaminase activity, to kinetically resolve aliphatic β-amino acid, and the corresponding structural gene (aptA) was cloned. The gene was functionally expressed in Escherichia coli BL21 by using an isopropyl-β-d-thiogalactopyranoside (IPTG)-inducible pET expression system (9.6 U/mg), and the recombinant AptA was purified to show a specific activity of 77.2 U/mg for l-β-amino-n-butyric acid (l-β-ABA). The enzyme converts various β-amino acids and amines to the corresponding β-keto acids and ketones by using pyruvate as an amine acceptor. The apparent Km and V max for l-β-ABA were 56 mM and 500 U/mg, respectively, in the presence of 10 mM pyruvate. In the presence of 10 mM l-β-ABA, the apparent Km and V max for pyruvate were 11 mM and 370 U/mg, respectively. The enzyme exhibits high stereoselectivity (E > 80) in the kinetic resolution of 50 mM d,l-β-ABA, producing optically pure d-β-ABA (99% enantiomeric excess) with 53% conversion.

Free Amino Acids in Citrullus vulgaris (Watermelon)

PEDIATRICS ◽  
1984 ◽  
Vol 73 (6) ◽  
pp. 879-879
Author(s):  
T. A. TEDESCO ◽  
S. A. BENFORD ◽  
R. C. FOSTER ◽  
L. A. BARNESS
Keyword(s):  
Amino Acids ◽  
Free Amino Acids ◽  
Free Amino ◽  
Neonatal Period ◽  
Essential Amino Acids ◽  
Solid Foods ◽  
Citrullus Vulgaris ◽  
Keto Acids ◽  
Wet Weight ◽  
Cycle Disorders

To the Editor.— Currently accepted dietary management of citrullinemia and other urea cycle disorders includes protein restriction, sodium benzoate, and dietary supplements of keto acids or essential amino acids with postblock intermediates such as arginine in citrullinemia and arginino-succinic aciduria. When a child survives the neonatal period on such a regimen and solid foods are introduced into the diet, there is at least one fruit that should be avoided, Citrullus Vulgaris, commonly known as watermelon. Quantitation of free amino acids extracted from 1 g wet weight of watermelon fruit yielded the following (in mmoles per gram wet weight): Phenylalanine, 1.25; histidine, 0.24; tryptophan, 0.35; lysine, 0.82; ornithine, 0.32; arginine, 11.36; aspartic acid, 0.97; threonine, 0.74; serine, 1.05; glutamine, 3.86; glutamic acid, 1.38; citrulline, 23.68; alanine, 1.15; valine, 0.17; isoleucine, 1.24; leucine, 0.24.

Formation of α-Keto Acids from α-Amino Acids by the Action of Free Radicals in Aqueous Solution

Science ◽  
1951 ◽  
Vol 114 (2964) ◽  
pp. 412-413
Author(s):  
G. R. A. Johnson ◽  
George Scholes ◽  
Joseph Weiss
Keyword(s):  
Aqueous Solution ◽  
Amino Acids ◽  
Free Radicals ◽  
Keto Acids

scholarly journals The Complex Compound of Amino Acids With Titanium (III) as a Method to Control and Synthesis of Different Structures of TiO2 Nanoparticles; Usage as Photocatalysts to Oxidize Alcohols to Aldehyde

2021 ◽  
Author(s):  
Yahya Absalan ◽  
Nazanin Noroozi Shad ◽  
Mostafa Gholizadeh
Keyword(s):  
Amino Acids ◽  
Titanium Dioxide ◽  
Uv Light ◽  
Chemical Analyses ◽  
Benzyl Alcohols ◽  
Titanium Dioxide Nanoparticle ◽  
Physical Chemical ◽  
Nitrobenzyl Alcohol ◽  
Different Types ◽  
Full Investigation

Abstract Different types of the amino acids (Glutamine, Glycine, Alanine) were used to coordinate TiCl3 in order to investigating the best precursor for synthesis of TiO2. Also, a full investigation was carried out to synthesis four different structures of TiO2 nanoparticles [TiO2 (A0.8R0.2), TiO2 (A0.6R0.4), TiO2 (Anatase), and TiO2 (Rutile)]. Oxidation of derivatives alcohol to their corresponding aldehyde through the obtained nanoparticles, as a photocatalyst, under UV light was considered to investigate the best structure of TiO2. Different physical-chemical analyses were applied to investigate the result. The result showed that the titanium dioxide nanoparticle, synthesized from glycine was obtained at the least temperature and was chosen as a precursor to synthesis of four different types of TiO2. All the synthesized TiO2 were applied for oxidation of benzyl alcohols into benzaldehyde, as a test, and TiO2 (A0.6R0.4) could give the best result (87% efficiency). Then it was used to oxidize benzyl alcohol, 4-cholorobenzyl alcohol, 4-nitrobenzyl alcohol and 4-methoxybenzyl alcohol to their corresponding aldehyde and efficiency were 74, 92, 87, and 65% respectively.

scholarly journals Ag(I)/TiO2-Photocatalyzed N-Methylation of Amino Acids with Methanol

2020 ◽  
Author(s):  
Yuna Morioka ◽  
Ivven Huang ◽  
Susumu Saito ◽  
Hiroshi Naka
Keyword(s):  
Amino Acids ◽  
Titanium Dioxide ◽  
Uv Light ◽  
Optical Purity

<div><div><div><p>Silver(I)-loaded titanium dioxide (AgNO3/TiO2) catalyzes the direct N-methylation of amino acids with methanol under irradiation with UV light. This method produces a variety of N-methyl and N,N-dimethyl amino acids with retention of their optical purity.</p></div></div></div>

Influence of branched-chain amino acids and branched-chain keto acids on protein synthesis in isolated hepatocytes

Hepatology ◽  
1987 ◽  
Vol 7 (2) ◽  
pp. 324-329 ◽  
Author(s):  
Wolfgang Base ◽  
Carl Barsigian ◽  
Alisa Schaeffer ◽  
Ellen Shaw ◽  
Jose Martinez ◽  
...  
Keyword(s):  
Amino Acids ◽  
Protein Synthesis ◽  
Isolated Hepatocytes ◽  
Branched Chain Amino Acids ◽  
Keto Acids ◽  
Branched Chain ◽  
Branched Chain Keto Acids

3-Ketoglutarate generation in pancreatic B-cell mitochondria regulates insulin secretory action of amino acids and 2-keto acids

1986 ◽  
Vol 6 (2) ◽  
pp. 163-169 ◽  
Author(s):  
S. Lenzen ◽  
W. Schmidt ◽  
I. Rustenbeck ◽  
U. Panten
Keyword(s):  
Amino Acids ◽  
Insulin Secretion ◽  
B Cell ◽  
Common Denominator ◽  
Pancreatic B Cell ◽  
Stimulate Insulin Secretion ◽  
Neutral Amino Acids ◽  
Keto Acids ◽  
Secretory Action ◽  
Pancreatic B Cells

The various neutral amino acids and aliphatic 2-keto acids exhibit differential effects on insulin secretion. The common denominator for all these effects is the 2-ketoglutarate generation in the pancreatic B-cell mitochondria. The neutral amino acids l-leucine and l-norvaline and the aliphatic ketomonocarboxylic acids 2-ketoisocaproate, 2-ketocaproate, 2-ketovalerate, and 2-keto-3-methylvalerate all stimulate insulin secretion and increase 2-ketoglutarate generation in pancreatic B-cell mitochondria through activation of glutamate dehydrogenase and transamination with l-glutamate and l-glutamine, respectively. The neutral amino acids l-valine, l-norleucine, and l-alanine and the aliphatic 2-keto acids 2-ketoisovalerate and pyruvate do not stimulate insulin secretion and do not increase 2-ketoglutarate generation in pancreatic B-cell mitochondria. Inhibition of 2-keto acid induced insulin secretion by l-valine and l-isoleucine is accompanied by reduced 2-ketoglutarate generation in pancreatic B-cell mitochondria. Thus intramitochondrial 2-ketoglutarate generation in pancreatic B-cells may regulate the insulin secretory potency of amino acids and 2-keto acids.

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