Engineering dithiobenzoic acid lactone-decorated Si-rhodamine as a highly selective near-infrared HOCl fluorescent probe for imaging drug-induced acute nephrotoxicity

2019 ◽  
Vol 55 (73) ◽  
pp. 10916-10919 ◽  
Author(s):  
Jinping Wang ◽  
Dan Cheng ◽  
Longmin Zhu ◽  
Peng Wang ◽  
Hong-Wen Liu ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Near Infrared ◽  
Drug Induced ◽  
Acid Lactone ◽  
First Time

A NIR fluorescent probe based on Si-rhodamine dithiobenzoic acid lactone was used to selectively visualize HOCl during GEN-induced nephrotoxicity for the first time.

scholarly journals In vivo imaging of leucine aminopeptidase activity in drug-induced liver injury and liver cancer via a near-infrared fluorescent probe

2017 ◽  
Vol 8 (5) ◽  
pp. 3479-3483 ◽  
Author(s):  
Xinyuan He ◽  
Lihong Li ◽  
Yu Fang ◽  
Wen Shi ◽  
Xiaohua Li ◽  
...  
Keyword(s):  
Liver Injury ◽  
Fluorescent Probe ◽  
In Vivo Imaging ◽  
Near Infrared ◽  
Leucine Aminopeptidase ◽  
Aminopeptidase Activity ◽  
Drug Induced ◽  
Drug Induced Liver Injury ◽  
First Time

The upregulation of leucine aminopeptidase in hepatopathy models is imaged in vivo for the first time with a near-infrared fluorescent probe.

Design, synthesis and application of a near-infrared fluorescent probe for in vivo imaging of aminopeptidase N

2017 ◽  
Vol 53 (68) ◽  
pp. 9438-9441 ◽  
Author(s):  
Xinyuan He ◽  
Yiming Hu ◽  
Wen Shi ◽  
Xiaohua Li ◽  
Huimin Ma
Keyword(s):  
Fluorescent Probe ◽  
In Vivo Imaging ◽  
Near Infrared ◽  
Aminopeptidase N ◽  
Design Synthesis ◽  
First Time

We have, for the first time, developed a near-infrared fluorescent probe for aminopeptidase N by combining a hemicyanine and an alanyl residue.

scholarly journals Synthesis, fluorescence property and cell imaging of a perylene diimide-based NIR fluorescent probe for hypochlorite with dual-emission fluorescence responses

2020 ◽  
Vol 1 (4) ◽  
pp. 814-819
Author(s):  
Huan-ren Cheng ◽  
Botao Qu ◽  
Chen Qian ◽  
Meng Xu ◽  
Ruiping Zhang
Keyword(s):  
Fluorescent Probe ◽  
Near Infrared ◽  
Cell Imaging ◽  
Fluorescence Property ◽  
Perylene Diimide ◽  
Dual Emission ◽  
First Time ◽  
Ratiometric Fluorescent Probe

In this study, for the first time, a novel near-infrared and ratiometric fluorescent probe was conveniently synthesized by reacting PDI-based salicylaldehyde with 2-(hydrazonomethyl)phenol.

A hepatocyte-targeting near-infrared ratiometric fluorescent probe for monitoring peroxynitrite during drug-induced hepatotoxicity and its remediation

2019 ◽  
Vol 55 (95) ◽  
pp. 14307-14310 ◽  
Author(s):  
Wen-Li Jiang ◽  
Yongfei Li ◽  
Wen-Xin Wang ◽  
Yi-Ting Zhao ◽  
Junjie Fei ◽  
...  
Keyword(s):  
Liver Injury ◽  
Fluorescent Probe ◽  
Near Infrared ◽  
Living Cells ◽  
Drug Induced ◽  
Drug Induced Liver Injury ◽  
Ratiometric Fluorescent Probe

A novel hepatocyte-targeting near-infrared ratiometric fluorescent probe named Gal-NIR is developed for detecting ONOO−. The probe can target the hepatocyte and assess drug-induced liver injury and its remediation in living cells and mice.

A reaction-based near-infrared fluorescent probe that can visualize endogenous selenocysteine in vivo in tumor-bearing mice

The Analyst ◽  
2018 ◽  
Vol 143 (20) ◽  
pp. 4860-4869 ◽  
Author(s):  
Ling Zhang ◽  
Xiaoning Kai ◽  
Yiran Zhang ◽  
Youguang Zheng ◽  
Yunsheng Xue ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Near Infrared ◽  
Tumor Bearing ◽  
First Time

Endogenously generated selenocysteine in tumor-bearing mice were selectively detected by our reaction-based NIR probe for the first time.

A two-photon excited near-infrared fluorescent probe for imaging peroxynitrite during drug-induced hepatotoxicity and its remediation

Talanta ◽  
2021 ◽  
Vol 221 ◽  
pp. 121607
Author(s):  
Guo-Jiang Mao ◽  
Guang-Qi Gao ◽  
Wen-Pei Dong ◽  
Qian-Qian Wang ◽  
Ying-Ying Wang ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Near Infrared ◽  
Drug Induced ◽  
Two Photon

scholarly journals Line observations of the 30-Dor complex and N159A5 with the MPE imaging NIR spectrometer FAST

1991 ◽  
Vol 148 ◽  
pp. 205-206 ◽  
Author(s):  
A. Krabbe ◽  
J. Storey ◽  
V. Rotaciuc ◽  
S. Drapatz ◽  
R. Genzel
Keyword(s):  
Spatial Resolution ◽  
Molecular Hydrogen ◽  
Near Infrared ◽  
Large Magellanic Cloud ◽  
Magellanic Cloud ◽  
Emission Lines ◽  
Resolving Power ◽  
Max Planck ◽  
First Time ◽  
Infrared Array

Images with subarcsec spatial resolution in the light of near-infrared atomic (Bry) and molecular hydrogen H2 (S(1) v=1-0) emission lines were obtained for some extended, pointlike objects in the Large Magellanic Cloud (LMC) for the first time. We used the Max-Planck-Institut für extraterrestrische Physik (MPE) near-infrared array spectrometer FAST (image scale 0.8”/pix, spectral resolving power 950) at the ESO/MPI 2.2m telescope, La Silla. We present some results on the 30-Dor complex and N159A5.

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