Molecular recognition of organophosphorus compounds in water and inhibition of their toxicity to acetylcholinesterase

2019 ◽  
Vol 55 (66) ◽  
pp. 9797-9800 ◽  
Author(s):  
Wei-Er Liu ◽  
Zhao Chen ◽  
Liu-Pan Yang ◽  
Ho Yu Au-Yeung ◽  
Wei Jiang
Keyword(s):  
Molecular Recognition ◽  
Organophosphorus Compounds ◽  
Fluorescent Sensor ◽  
Molecular Tubes

endo-Functionalized molecular tubes are able to recognize toxic organophosphorus compounds in water. They can be used as a fluorescent sensor and as an inhibitor to reduce the toxicity of paraoxon to acetylcholinesterase.

Molecular Recognition and Chirality Sensing of Epoxides in Water Using Endo-Functionalized Molecular Tubes

2017 ◽  
Vol 139 (25) ◽  
pp. 8436-8439 ◽  
Author(s):  
Li-Li Wang ◽  
Zhao Chen ◽  
Wei-Er Liu ◽  
Hua Ke ◽  
Sheng-Hua Wang ◽  
...  
Keyword(s):  
Molecular Recognition ◽  
Molecular Tubes

scholarly journals A Novel p-Nitroaniline Fluorescent Sensor Based on Molecular Recognition of Carboxymethyl-β-cyclodextrin-capped ZnO/ZnS/MgO Nanocomposites

2011 ◽  
Vol 27 (8) ◽  
pp. 851 ◽  
Author(s):  
Qianqian GAO ◽  
Fei LIU ◽  
Yuzhu JIANG ◽  
Huajun DAI ◽  
Tianhua FU ◽  
...  
Keyword(s):  
Molecular Recognition ◽  
Fluorescent Sensor

Bis(β-cyclodextrin)s Linked with an Aromatic Diamine as Fluorescent Sensor for the Molecular Recognition of Bile Salts

2009 ◽  
Vol 38 (4) ◽  
pp. 417-428 ◽  
Author(s):  
Yan Zhao ◽  
Juan Gu ◽  
Shao Ming Chi ◽  
Yong Cun Yang ◽  
Hong You Zhu ◽  
...  
Keyword(s):  
Molecular Recognition ◽  
Bile Salts ◽  
Fluorescent Sensor ◽  
Aromatic Diamine

Dansyl-Modified ?-Cyclodextrin as a fluorescent sensor for molecular recognition

1994 ◽  
Vol 15 (3) ◽  
pp. 273-279 ◽  
Author(s):  
Fumio Hamada ◽  
Yoshihiko Kondo ◽  
Riko Ito ◽  
Iwao Suzuki ◽  
Tetsuo Osa ◽  
...  
Keyword(s):  
Molecular Recognition ◽  
Fluorescent Sensor ◽  
Modified Cyclodextrin

A Three-Dimensional Tetraphenylethylene-Based Fluorescence Covalent Organic Framework for Molecular Recognition

2020 ◽  
Author(s):  
Junxia Ren ◽  
Yaozu Liu ◽  
Xin Zhu ◽  
Yangyang Pan ◽  
Yujie Wang ◽  
...  
Keyword(s):  
Molecular Recognition ◽  
Fluorescence Probe ◽  
Three Dimensional ◽  
Hazardous Substances ◽  
Covalent Organic Framework ◽  
Highly Sensitive ◽  
Volatile Organic ◽  
Polycyclic Aromatic ◽  
Better Than ◽  
Organic Framework

<p><a></a><a></a><a></a><a></a><a></a><a></a><a></a><a>The development of highly-sensitive recognition of </a><a></a><a></a><a></a><a></a><a>hazardous </a>chemicals, such as volatile organic compounds (VOCs) and polycyclic aromatic hydrocarbons (PAHs), is of significant importance because of their widespread social concerns related to environment and human health. Here, we report a three-dimensional (3D) covalent organic framework (COF, termed JUC-555) bearing tetraphenylethylene (TPE) side chains as an aggregation-induced emission (AIE) fluorescence probe for sensitive molecular recognition.<a></a><a> </a>Due to the rotational restriction of TPE rotors in highly interpenetrated framework after inclusion of dimethylformamide (DMF), JUC-555 shows impressive AIE-based strong fluorescence. Meanwhile, owing to the large pore size (11.4 Å) and suitable intermolecular distance of aligned TPE (7.2 Å) in JUC-555, the obtained material demonstrates an excellent performance in the molecular recognition of hazardous chemicals, e.g., nitroaromatic explosives, PAHs, and even thiophene compounds, via a fluorescent quenching mechanism. The quenching constant (<i>K</i><sub>SV</sub>) is two orders of magnitude better than those of other fluorescence-based porous materials reported to date. This research thus opens 3D functionalized COFs as a promising identification tool for environmentally hazardous substances.</p>

Biomimetic Extracellular Vesicles Embedded with Black Phosphorus for Molecular Recognition-Guided Biomineralization

2018 ◽  
Author(s):  
Yingqian Wang ◽  
Xiaoxia Hu ◽  
Lingling Zhang ◽  
Chunli Zhu ◽  
Jie Wang ◽  
...  
Keyword(s):  
Molecular Recognition ◽  
Extracellular Vesicles ◽  
Inorganic Phosphate ◽  
Physiological Activity ◽  
Medical Engineering ◽  
Matrix Vesicles ◽  
Black Phosphorus ◽  
Photothermal Effect ◽  
Biological Processes ◽  
Extracellular Environment

Extracellular vesicles (EVs) are involved in the regulation of cell physiological activity and the reconstruction of extracellular environment. Matrix vesicles (MVs) are a type of EVs, and they participate in the regulation of cell mineralization. Herein, bioinspired MVs embedded with black phosphorus are functionalized with cell-specific aptamer (denoted as Apt-bioinspired MVs) for stimulating biomineralization. The aptamer can direct bioinspired MVs to targeted cells, and the increasing concentration of inorganic phosphate originated from the black phosphorus can facilitate cell biomineralization. The photothermal effect of the Apt-bioinspired MVs also positively affects mineralization. In addition, the Apt-bioinspired MVs display outstanding bone regeneration performance. Considering the excellent behavior of the Apt-bioinspired MVs for promoting biomineralization, our strategy provides a way of designing bionic tools for studying the mechanisms of biological processes and advancing the development of medical engineering.<br>

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