A bioartificial liver support system integrated with a DLM/GelMA-based bioengineered whole liver for prevention of hepatic encephalopathy via enhanced ammonia reduction

Guohua Wu; Di Wu; James Lo; Yimin Wang; Jianguo Wu; Siming Lu; Han Xu; Xin Zhao; Yong He; Jun Li; Utkan Demirci; Shuqi Wang

doi:10.1039/c9bm01879d

A bioartificial liver support system integrated with a DLM/GelMA-based bioengineered whole liver for prevention of hepatic encephalopathy via enhanced ammonia reduction

Biomaterials Science ◽

10.1039/c9bm01879d ◽

2020 ◽

Vol 8 (10) ◽

pp. 2814-2824

Author(s):

Guohua Wu ◽

Di Wu ◽

James Lo ◽

Yimin Wang ◽

Jianguo Wu ◽

...

Keyword(s):

Hepatic Encephalopathy ◽

Support System ◽

Bioartificial Liver ◽

Liver Support ◽

Liver Support System ◽

Bioartificial Liver Support ◽

Liver Functions ◽

Decellularized Liver

The developed bioartificial liver support system integrated with the decellularized liver matrix/GelMA-based bioengineered whole liver can potentially help elevate liver functions and prevent hepatic encephalopathy via enhanced ammonia reduction.

Download Full-text

A novel configuration of bioartificial liver support system based on circulating microcarrier culture

Artificial Cells Blood Substitutes and Biotechnology ◽

10.3109/10731190009119359 ◽

2000 ◽

Vol 28 (4) ◽

pp. 273-291 ◽

Cited By ~ 5

Author(s):

Q. Shi ◽

R. Mirteregger ◽

D. Falkenhagen ◽

Y. T. Yu

Keyword(s):

Support System ◽

Bioartificial Liver ◽

Microcarrier Culture ◽

Liver Support ◽

Liver Support System ◽

Bioartificial Liver Support

Download Full-text

Expression and Amplification of Glutamine Synthetase Gene for Constructing Ammonia-Metabolizing Cell Lines in Hybrid Bioartificial Liver Support System

Animal Cell Technology: Basic & Applied Aspects ◽

10.1007/978-94-017-0728-2_47 ◽

2002 ◽

pp. 263-267

Author(s):

Takeshi Omasa ◽

Kazumi Kim ◽

Shin-ya Hiramatsu ◽

Yoshio Katakura ◽

Michimasa Kishimoto ◽

...

Keyword(s):

Glutamine Synthetase ◽

Cell Lines ◽

Support System ◽

Bioartificial Liver ◽

Liver Support ◽

Glutamine Synthetase Gene ◽

Liver Support System ◽

Bioartificial Liver Support

Download Full-text

CLINICAL EXPERIENCE WITH A NOVEL BIOARTIFICIAL LIVER SUPPORT SYSTEM

ASAIO Journal ◽

10.1097/00002480-199903000-00317 ◽

1999 ◽

Vol 45 (2) ◽

pp. 202

Author(s):

JF Patzer ◽

GV Mazariegos ◽

DJ Kramer ◽

R Lopez ◽

M Giraldo ◽

...

Keyword(s):

Clinical Experience ◽

Support System ◽

Bioartificial Liver ◽

Liver Support ◽

Liver Support System ◽

Bioartificial Liver Support

Download Full-text

The HepatAssist® Bioartificial Liver Support System: clinical study and pig hepatocyte process

Expert Opinion on Investigational Drugs ◽

10.1517/13543784.8.3.229 ◽

1999 ◽

Vol 8 (3) ◽

pp. 229-235 ◽

Cited By ~ 31

Author(s):

Claudy Mullon ◽

Zorina Pitkin

Keyword(s):

Clinical Study ◽

Support System ◽

Bioartificial Liver ◽

Liver Support ◽

Liver Support System ◽

Bioartificial Liver Support

Download Full-text

Bioengineering the Liver: Scale-Up and Cool Chain Delivery of the Liver Cell Biomass for Clinical Targeting in a Bioartificial Liver Support System

BioResearch Open Access ◽

10.1089/biores.2012.0286 ◽

2013 ◽

Vol 2 (1) ◽

pp. 1-11 ◽

Cited By ~ 30

Author(s):

Eloy Erro ◽

James Bundy ◽

Isobel Massie ◽

Sherri-Ann Chalmers ◽

Aude Gautier ◽

...

Keyword(s):

Support System ◽

Liver Cell ◽

Scale Up ◽

Bioartificial Liver ◽

Liver Support ◽

Liver Support System ◽

Cell Biomass ◽

Bioartificial Liver Support

Download Full-text

Evaluation of a bioartificial liver support system in anhepatic pigs

Journal of Hepatology ◽

10.1016/s0168-8278(00)80532-2 ◽

2000 ◽

Vol 32 ◽

pp. 52

Author(s):

M.N. Sosef ◽

S.L. Abrahamse ◽

R.A.F.M. Chamuleau ◽

T.M. van Gulik

Keyword(s):

Support System ◽

Bioartificial Liver ◽

Liver Support ◽

Liver Support System ◽

Bioartificial Liver Support

Download Full-text

Evaluation of a bioartificial liver support system in anhepatic pigs

European Journal of Gastroenterology & Hepatology ◽

10.1097/00042737-199912000-00257 ◽

1999 ◽

Vol 11 (12) ◽

pp. A98

Author(s):

M. N. Sosef ◽

S. L Abrahamse ◽

RAEM. Chamuleau ◽

T. M. van Gulik

Keyword(s):

Support System ◽

Bioartificial Liver ◽

Liver Support ◽

Liver Support System ◽

Bioartificial Liver Support

Download Full-text

First clinical application of a second generation HepatAssist bioartificial liver support system without charcoal associated with neurological recovery in a fulminant hepatic failure patient

Gastroenterology ◽

10.1016/s0016-5085(08)82696-0 ◽

2001 ◽

Vol 120 (5) ◽

pp. A543 ◽

Cited By ~ 1

Author(s):

Nikolaos Arkadopoulos ◽

Maria Alexandri ◽

Nikiforita Poulakaki ◽

Apostolos Papalois ◽

Dimitris Papadimitriou ◽

...

Keyword(s):

Clinical Application ◽

Support System ◽

Fulminant Hepatic Failure ◽

Hepatic Failure ◽

Second Generation ◽

Bioartificial Liver ◽

Neurological Recovery ◽

Liver Support ◽

Liver Support System ◽

Bioartificial Liver Support

Download Full-text

Construction of modular novel bioartificial liver support system

10.1109/iembs.2009.5332545 ◽

2009 ◽

Author(s):

Jianfeng Liu ◽

Tao Song ◽

Wei Jiang ◽

Yimin Zhang ◽

Guoliang Lv ◽

...

Keyword(s):

Support System ◽

Bioartificial Liver ◽

Liver Support ◽

Liver Support System ◽

Bioartificial Liver Support

Download Full-text

Experimental research on TECA-I bioartificial liver support system to treat canines with acute liver failure

World Journal of Gastroenterology ◽

10.3748/wjg.7.5.706 ◽

2001 ◽

Vol 7 (5) ◽

pp. 706 ◽

Cited By ~ 1

Author(s):

Xiao-Ping Chen ◽

Yi-Long Xue ◽

Xin-Jian Li ◽

Zuo-Yun Zhang ◽

Yan-Ling Li ◽

...

Keyword(s):

Liver Failure ◽

Acute Liver Failure ◽

Experimental Research ◽

Support System ◽

Bioartificial Liver ◽

Liver Support ◽

Liver Support System ◽

Bioartificial Liver Support

Download Full-text