Molecularly imprinted polymers for miniaturized sample preparation techniques: strategies for chromatographic and mass spectrometry methods

2020 ◽  
Vol 12 (7) ◽  
pp. 894-911 ◽  
Author(s):  
H. Santos ◽  
R. O. Martins ◽  
D. A. Soares ◽  
A. R. Chaves
Keyword(s):  
Mass Spectrometry ◽  
Sample Preparation ◽  
Molecularly Imprinted Polymers ◽  
Small Scale ◽  
Molecularly Imprinted ◽  
Imprinted Polymers ◽  
Preparation Techniques

Small-scale innovations with MIP applications in chromatography and mass spectrometry methods.

scholarly journals Fast quantification of fluoroquinolones in environmental water samples using molecularly imprinted polymers coupled with internal extractive electrospray ionization mass spectrometry

RSC Advances ◽  
2018 ◽  
Vol 8 (31) ◽  
pp. 17293-17299 ◽  
Author(s):  
Wei Kou ◽  
Hua Zhang ◽  
Aisha Bibi ◽  
Mufang Ke ◽  
Jing Han ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Molecularly Imprinted Polymers ◽  
Water Samples ◽  
High Sensitivity ◽  
Environmental Water ◽  
Environmental Water Samples ◽  
Ionization Mass ◽  
Molecularly Imprinted ◽  
Imprinted Polymers ◽  
Sensitivity Method

A simple, fast and high-sensitivity method for quantification of fluoroquinolones in environmental water samples using MIPs-iEESI-MS.

A High-Throughput Screening of N-Carbobenzoxy-L-Tryptophan Imprinted Polymers and their Application for Monolithic Chiral Stationary Phase

2012 ◽  
Vol 535-537 ◽  
pp. 1525-1528 ◽  
Author(s):  
Jian Qi ◽  
Li Guo ◽  
Hai Feng Sang
Keyword(s):  
Stationary Phase ◽  
Molecularly Imprinted Polymers ◽  
High Throughput Screening ◽  
Chiral Stationary Phase ◽  
Binding Capacity ◽  
Low Cost ◽  
Small Scale ◽  
Molecularly Imprinted ◽  
Imprinted Polymers ◽  
Chiral Selectivity

Molecular imprinting is a technique to prepare polymers with predetermined selectivity, specific recognition and predesigned affinity to a desired molecule. The stability and low cost of molecularly imprinted polymers (MIPs) render them attractive for a broad range of applications. Currently, MIP technique has been widely used in chiral separation. In this study, a series of molecularly imprinted polymers for N-Carbobenzoxy-L-tryptophan (N-Cbz-L-Trp) synthesized in different conditions were prepared in a small scale to simulate the monolithic chiral stationary phases (CSPs) primarily. By coupling in situ processing and batch rebinding evaluation, the type of functional monomers, which likely to affect the chiral selectivity of MIPs, was investigated. It was found that a MIP comprising a mixture of functional monomer 4-vinylpyridine (4-VP) and porogen 1-dodecanol/toluene exhibited the highest binding capacity and chiral selectivity for N-Carbobenzoxy-L-tryptophan. Thereafter, the monolithic MIP synthesized in screened optimum condition is used as chiral stationary phase in HPLC, which shows favourable separating capacity.

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