Sensitive and selective detection of microRNA in complex biological samples based on protein-enhanced fluorescence anisotropy

2020 ◽  
Vol 12 (5) ◽  
pp. 687-692 ◽  
Author(s):  
Yan Li ◽  
Yao Sun ◽  
Jieyun Ye ◽  
Fengping Pan ◽  
Bo Peng ◽  
...  
Keyword(s):  
Molecular Mass ◽  
Biological Samples ◽  
Fluorescence Anisotropy ◽  
High Sensitivity ◽  
Selective Detection ◽  
Enhanced Fluorescence ◽  
Sensitivity And Selectivity

A molecular mass amplifying strategy to construct a fluorescence anisotropy sensor for the detection of microRNA with high sensitivity and selectivity in complex biological samples was proposed.

scholarly journals Sensitive and selective detection of the highly toxic pesticide carbofuran in vegetable samples by a molecularly imprinted electrochemical sensor with signal enhancement by AuNPs

RSC Advances ◽  
2018 ◽  
Vol 8 (45) ◽  
pp. 25334-25341 ◽  
Author(s):  
Peipei Qi ◽  
Jiao Wang ◽  
Xiangyun Wang ◽  
Zhiwei Wang ◽  
Hao Xu ◽  
...  
Keyword(s):  
Electrochemical Sensor ◽  
High Sensitivity ◽  
Signal Enhancement ◽  
Selective Detection ◽  
Molecularly Imprinted ◽  
Vegetable Samples ◽  
Sensitivity And Selectivity

An imprinted electrochemical sensor was constructed for the detection of carbofuran with high sensitivity and selectivity.

Cacodylate sensor and its application for the determination of amino acid levels in biological samples

2020 ◽  
Author(s):  
Hisham S M Abd-Rabboh ◽  
Ayman H Kamel ◽  
Fuziah H A Alshehri
Keyword(s):  
Biological Samples ◽  
Electrochemical Sensors ◽  
Response Times ◽  
Reference Electrode ◽  
High Sensitivity ◽  
Life Time ◽  
Polymeric Membrane ◽  
Time Signal ◽  
Sensitivity And Selectivity ◽  
Environmental And Biological Samples

Abstract Background The importance of recognizing and quantifying chemical anions/cations found in various types of samples, including environmental and biological samples, is extensively studied. Recent findings suggest the possibility of health risk caused by organic dimethylarsininc acid (DMAs) compound itself, not its arsenic inorganic metabolite. Objective This article aims to fabricate polymeric-membrane electrochemical sensors with high sensitivity and selectivity for dimethylarsinate (cacodylic acid sodium salt, DMAs) based on silver diethyldithiocarbamate (AgDDTC) and CuIIphthalocyanine (CuPC) as novel neutral carriers and their applications. Methods DMAs calibration relations and titrations were carried out using a potentiometric workstation equipped with a double-junction reference electrode, in conjunction with the fabricated working electrodes. Results Sensors revealed fast and stable anionic response with near-Nernstian slopes (-38.6 ± 0.9 and -31.5 ± 0.6 mV/decade), within concentration ranges (1.7x10−5 - 1.0x10−2 and 3.0x10−5 - 1.0x10−2 M) and detection limits (1.0x10−5 and 1.6x10−5 M) for AgDDTC- and CuPC-based sensors, respectively. Sensors are characterized with their extended life-time, signal stability, high precision and short response times. Selectivity for cacodylate anion over most common anions is tested for proposed electrodes. Sensors were satisfactorily applied for DMAs quantification in biological matrices with recoveries ranging between 96.2 and 99.0%. Membrane sensors were interfaced with a flow-through system for continuous monitoring of DMAs. The sensors were tested for the assay of different amino acids based on their reaction with cacodylate, where reaction end-points were monitored with the proposed electrodes using direct potentiometric determination and flow injection analysis (FIA).

A novel luminescent Pb(ii) – organic framework exhibiting a rapid and selective detection of trace amounts of NACs and Fe3+ with excellent recyclability

2017 ◽  
Vol 46 (19) ◽  
pp. 6303-6311 ◽  
Author(s):  
Xuan Luo ◽  
Xiao Zhang ◽  
Yuanling Duan ◽  
Xiaolin Wang ◽  
Jiaming Zhao
Keyword(s):  
Fluorescent Probe ◽  
High Sensitivity ◽  
Selective Detection ◽  
Nitroaromatic Explosives ◽  
Sensitivity And Selectivity ◽  
Organic Framework

A novel Pb MOF used as a fluorescent probe for nitroaromatic explosives and Fe3+ shows high sensitivity and selectivity.

A novel FRET-based fluorescent probe for the selective detection of hydrogen sulfide (H2S) and its application for bioimaging

2018 ◽  
Vol 6 (30) ◽  
pp. 4903-4908 ◽  
Author(s):  
Qi Zhao ◽  
Fangjun Huo ◽  
Jin Kang ◽  
Yongbin Zhang ◽  
Caixia Yin
Keyword(s):  
Hydrogen Sulfide ◽  
Detection Limit ◽  
Fluorescent Probe ◽  
Nude Mice ◽  
High Sensitivity ◽  
Fast Response ◽  
Living Cells ◽  
Selective Detection ◽  
Low Detection Limit ◽  
Sensitivity And Selectivity

Herein, our group developed a fast response fluorescent probe (Flu-N3) for H2S on the basis of the 7-amino-4-methylcoumarin and fluorescein FRET system with high sensitivity and selectivity and a low detection limit of 0.031 μM. Moreover, the probe was successfully applied to image exogenous and endogenous H2S in living cells and nude mice.

2D luminescent metal–organic framework: efficient and highly selective detection of 2,4,6-trinitrophenol at the ppb level

CrystEngComm ◽  
2021 ◽  
Author(s):  
Ming Yue Fan ◽  
Peng Fu ◽  
Jiao Li ◽  
Zhong Min Su ◽  
Xiao Li ◽  
...  
Keyword(s):  
Metal Organic Framework ◽  
High Sensitivity ◽  
Fluorescence Signal ◽  
Selective Detection ◽  
Quenching Mechanism ◽  
Naked Eye ◽  
Sensitivity And Selectivity ◽  
Metal Organic ◽  
Organic Framework

A 2D Cd-MOF (CUST-531) was reported as a sensor to detect TNP with high sensitivity and selectivity. The quenching mechanism is the turn-off response of the fluorescence signal, which can be observed by the naked eye under UV-vis lamp irradiation.

Schottky diodes based on 2D materials for environmental gas monitoring: a review on emerging trends, recent developments and future perspectives

2021 ◽  
Author(s):  
Minu Mathew ◽  
Chandra Sekhar Rout
Keyword(s):  
Gas Sensing ◽  
2D Materials ◽  
Schottky Diodes ◽  
High Sensitivity ◽  
Future Perspectives ◽  
Working Temperature ◽  
Emerging Trends ◽  
Gas Sensing Properties ◽  
Recent Developments ◽  
Sensitivity And Selectivity

This review details the fundamentals, working principles and recent developments of Schottky junctions based on 2D materials to emphasize their improved gas sensing properties including low working temperature, high sensitivity, and selectivity.

Lanthanide coordination polymer-based biosensor for citrate detection in urine

2019 ◽  
Vol 11 (10) ◽  
pp. 1405-1409 ◽  
Author(s):  
Haoshuang Shen ◽  
Baoxia Liu ◽  
Daosheng Liu ◽  
Xu Zhu ◽  
Xiuhua Wei ◽  
...  
Keyword(s):  
Coordination Polymer ◽  
High Sensitivity ◽  
Lanthanide Coordination Polymer ◽  
Sensitivity And Selectivity

GMP ligand based LCP sensor for Cit with high sensitivity and selectivity was constructed.

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