Nitrogen and phosphorus co-doped carbon dots as a “turn-off-on” fluorescence probe for the detection of Hg2+ and GSH and cell imaging

2019 ◽  
Vol 11 (45) ◽  
pp. 5803-5809 ◽  
Author(s):  
Xuefang Yang ◽  
Mengting Zhang ◽  
Yulu Zhang ◽  
Ning Wang ◽  
Wei Bian ◽  
...  
Keyword(s):  
Carbon Dots ◽  
Cell Imaging ◽  
Fluorescence Probe ◽  
Raw Materials ◽  
Citric Acid Monohydrate ◽  
Hydrogen Phosphate ◽  
Nitrogen And Phosphorus ◽  
Doped Carbon Dots ◽  
Diammonium Hydrogen ◽  
Co Doped

Nitrogen and phosphorus co-doped carbon dots (NPCDs) were synthesized by a microwave method, using citric acid monohydrate and diammonium hydrogen phosphate as raw materials.

Nitrogen and phosphorus co-doped carbon dots derived from lily bulbs for copper ion sensing and cell imaging

2018 ◽  
Vol 83 ◽  
pp. 272-278 ◽  
Author(s):  
Dan Gu ◽  
Pingbo Zhang ◽  
Lei Zhang ◽  
Hao Liu ◽  
Zhanbin Pu ◽  
...  
Keyword(s):  
Carbon Dots ◽  
Cell Imaging ◽  
Copper Ion ◽  
Nitrogen And Phosphorus ◽  
Ion Sensing ◽  
Doped Carbon Dots ◽  
Co Doped

Nitrogen and Sulfur Co-doped Fluorescent Carbon Dots for the Detection of Morin and Cell Imaging

2018 ◽  
Vol 15 (1) ◽  
pp. 47-55
Author(s):  
Xuebing Li ◽  
Haifen Yang ◽  
Ning Wang ◽  
Tijian Sun ◽  
Wei Bian ◽  
...  
Keyword(s):  
Microwave Heating ◽  
Fluorescent Probe ◽  
Fluorescence Intensity ◽  
Carbon Dots ◽  
Cell Imaging ◽  
Water Soluble ◽  
Heating Process ◽  
X Ray ◽  
Doped Carbon Dots ◽  
Co Doped

Background: Morin has many pharmacological functions including antioxidant, anticancer, anti-inflammatory, and antibacterial effects. It is commonly used in the treatment of antiviral infection, gastropathy, coronary heart disease and hepatitis B in clinic. However, researches have shown that morin is likely to show prooxidative effects on the cells when the amount of treatment is at high dose, leading to the decrease of intracellular ATP levels and the increase of necrosis process. Therefore, it is necessary to determine the concentration of morin in biologic samples. Method: Novel water-soluble and green nitrogen and sulfur co-doped carbon dots (NSCDs) were prepared by a microwave heating process with citric acid and L-cysteine. The fluorescence spectra were collected at an excitation wavelength of 350 nm when solutions of NSCDs were mixed with various concentrations of morin. Results: The as-prepared NSCDs were characterized by transmission electron microscopy, X-ray diffraction and X-ray photoelectron spectroscopy. The fluorescence intensity of NSCDs decreased significantly with the increase of morin concentration. The fluorescence intensity of NSCDs displayed a linear response to morin in the concentration 0.10-30 μM with a low detection limit of 56 nM. The proposed fluorescent probe was applied to analysis of morin in human body fluids with recoveries of 98.0-102%. Conclusion: NSCDs were prepared by a microwave heating process. The present analytical method is sensitive to morin. The quenching process between NSCDs and morin is attributed to the static quenching. In addition, the cellular toxicity on HeLa cells indicated that the as-prepared NSCDs fluorescent probe does not show obvious cytotoxicity in cell imaging. Our proposed method possibly opens up a rapid and nontoxic way for preparing heteroatom doped carbon dots with a broad application prospect.

Green and Simple Synthesis of Photoluminescence-Tunable Carbon Dots for Sensing and Cell Imaging Applications

2021 ◽  
Vol 21 (12) ◽  
pp. 6101-6110
Author(s):  
Dong Sun ◽  
Shu-Jun Li ◽  
Chun-Feng Wang ◽  
Tian-Tian Liu ◽  
Guang-Yue Bai ◽  
...  
Keyword(s):  
Boric Acid ◽  
Carbon Dots ◽  
Luminescence Property ◽  
Cell Imaging ◽  
Fluorescence Emission ◽  
Fluorescent Imaging ◽  
Simple Synthesis ◽  
Low Toxicity ◽  
Doped Carbon Dots ◽  
Co Doped

Innovative nitrogen and boron co-doped carbon dots are hydrothermally produced using fructose, urea, and boric acid as precursors. The synthesized carbon dots possess a uniform morphology, and exhibit excellent fluorescence stability, tunable luminescence property, strong resistance to photobleaching, low-toxicity, and excellent biocompatibility. It is also found more dopant urea is conducive to the formation of the carbon dots with more B–N bonds, and shorter wavelength of fluorescence emission. Meanwhile, the synthesized carbon dots are well utilized as a photoluminescent probe for facile Hg2+ determination and fluorescent imaging reagent in cells.

scholarly journals An easy synthesis of nitrogen and phosphorus co-doped carbon dots as a probe for chloramphenicol

RSC Advances ◽  
2020 ◽  
Vol 10 (54) ◽  
pp. 32919-32926
Author(s):  
Pengli Zuo ◽  
Zhongguang Chen ◽  
Fengling Yu ◽  
Jinyu Zhang ◽  
Wei Zuo ◽  
...  
Keyword(s):  
Carbon Dots ◽  
Nitrogen And Phosphorus ◽  
Doped Carbon Dots ◽  
Co Doped

The spontaneous synthesis of nitrogen and phosphorus co-doped carbon dots was reported, and they were used as a probe for chloramphenicol.

scholarly journals Detection of Ferric Ions and Catecholamine Neurotransmitters via Highly Fluorescent Heteroatom Co-Doped Carbon Dots

Sensors ◽  
2020 ◽  
Vol 20 (12) ◽  
pp. 3470
Author(s):  
Thi Hoa Le ◽  
Hyun Jong Lee ◽  
Ji Hyeon Kim ◽  
Sang Joon Park
Keyword(s):  
Carbon Dots ◽  
Fluorescence Quantum Yield ◽  
Limit Of Detection ◽  
Fluorescence Signal ◽  
Ferric Ions ◽  
Nitrogen And Phosphorus ◽  
Fluorescence Detector ◽  
Sensing System ◽  
Doped Carbon Dots ◽  
Co Doped

Carbon dots (CDs) demonstrate very poor fluorescence quantum yield (QY). In this study, with the help of a hydrothermal method, we combined CDs with nitrogen and phosphorus elements belonging to the VA group (in the periodic table) to form heteroatom co-doped CDs, i.e., nitrogen and phosphorus co-doped carbon dots (NPCDs). These displayed a significant improvement in the QY (up to 84%), which was as much as four times than that of CDs synthesized by the same method. The as-prepared NPCDs could be used as an “off-on” fluorescence detector for the rapid and effective sensing of ferric ions (Fe3+) and catecholamine neurotransmitters (CNs) such as dopamine (DA), adrenaline (AD), and noradrenaline (NAD). The fluorescence of NPCDs was “turned off” and the emission wavelength was slightly red-shifted upon increasing the Fe3+ concentration. However, when CNs were incorporated, the fluorescence of NPCDs was recovered in a short response time; this indicated that CN concentration could be monitored, relying on enhancing the fluorescence signal of NPCDs. As a result, NPCDs are considered as a potential fluorescent bi-sensor for Fe3+ and CN detection. Particularly, in this research, we selected DA as the representative neurotransmitter of the CN group along with Fe3+ to study the sensing system based on NPCDs. The results exhibited good linear ranges with a limit of detection (LOD) of 0.2 and 0.1 µM for Fe3+ and DA, respectively.

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