Magnetic graphene oxide decorated with chitosan and Au nanoparticles: synthesis, characterization and application for detection of trace rhodamine B

2019 ◽  
Vol 11 (30) ◽  
pp. 3837-3843 ◽  
Author(s):  
Lili Xu ◽  
Hongbo Suo ◽  
Jianling Wang ◽  
Feixiang Cheng ◽  
Houmei Liu ◽  
...  

A novel magnetic graphene oxide modified with Au nanoparticles (Fe3O4@CS/GO/Au) as an efficient adsorbent was prepared for the detection of rhodamine B (RB) coupled with fluorescence spectrophotometry.

2017 ◽  
Vol 100 (5) ◽  
pp. 1544-1550 ◽  
Author(s):  
Mustafa Soylak ◽  
Demet Acar ◽  
Erkan Yilmaz ◽  
Sherif A El-Khodary ◽  
Mohamed Morsy ◽  
...  

Abstract The separation and preconcentration of copper(II), lead(II), and cadmium(II) ions on magnetic graphene oxide (MGO) by solid-phase extraction was carried out. Quantitative recovery was obtained by adsorption of analytes on MGO at pH 6 and elution of 3 M HNO3 in 10% acetone. To optimize the presented method, the effects of various parameters—including pH, eluent conditions, and vortex time—were examined. Matrix effects were also investigated. Mean recoveries of the analytes were between 95and 105%. The proposed method was validated by applying it to certified reference materials. Addition and recovery tests were also performed. The method wasapplied to verify the analyte content of several water and food samples.


ACS Omega ◽  
2021 ◽  
Author(s):  
Ting Guo ◽  
Chaoke Bulin ◽  
Zeyu Ma ◽  
Bo Li ◽  
Yanghuan Zhang ◽  
...  

2020 ◽  
Vol 20 (9) ◽  
pp. 1094-1104 ◽  
Author(s):  
Omid Arjmand ◽  
Mehdi Ardjmand ◽  
Ali M. Amani ◽  
Mohmmad H. Eikani

Background: Doxorubicin, as a strong anti-cancer agent for clinical treatment of various cancer types along with other drugs, is widely utilized. Due to the physiology of the human body and cancerous tissues, the applicability of doxorubicin is still limited and the targeted treatment of the different types of cancers is considered. Also, the side effects of the conventional forms of chemotherapy medicines, damaging and stressing the normal cells are considerable. Objective: This study introduces a novel and effective system for the targeted release of doxorubicin by successfully fabricating the green magnetic graphene oxide, chitosan, allium sativum, and quercus nanocomposite. Methods: The in vitro release of doxorubicin loaded on the nanocomposite was evaluated and investigated at pH 7.4 and 6.5, respectively. The drug diffusivity in the plasma environment was assessed for a more accurate analysis of the drug diffusion process. The nanocomposite loaded drug release mechanism and kinetics, as well as cytotoxicity assay was investigated. Results: The efficiency of the drug encapsulation was significantly enhanced using natural extract ingredients and consequently, the efficacy of the targeted treatment of cancerous tissues was improved. The developed nanocomposite provided a controlled release of doxorubicin in similar acidic conditions of the normal and cancerous cells and affirming that the fabricated system is thoroughly pH-dependent. Conclusion: The cytotoxicity assay confirmed that the fabricated nanocomposite at a high growth rate of cancerous cells has an anticancer property and acts as a toxic agent against tumor cells, suggesting that in conjunction with doxorubicin, it can be highly improved for killing cancerous cells.


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