Ag+-coordinated oligonucleotides on gold nanoparticles for anodic-stripping voltammetric immunoassay of cancer antigen 125 for cervical carcinoma

2019 ◽  
Vol 11 (23) ◽  
pp. 2976-2982
Author(s):  
Huifeng Xue ◽  
Jinwen Zheng ◽  
Qiaoyun Chen ◽  
Qingshui Wang ◽  
Yao Lin ◽  
...  

A simple and enzyme-free electrochemical immunoassay was developed for the sensitive screening of cancer antigen 125 using anodic-stripping voltammetry.

2016 ◽  
Vol 14 (9) ◽  
pp. 955-960 ◽  
Author(s):  
Khaoula Zinoubi ◽  
Yosra Braham ◽  
Houcine Barhoumi ◽  
Messaoud Benounis ◽  
Nicole Jaffrezic

2012 ◽  
Vol 2012 ◽  
pp. 1-5 ◽  
Author(s):  
Stéphane Fierro ◽  
Takeshi Watanabe ◽  
Kazumi Akai ◽  
Mikito Yamanuki ◽  
Yasuaki Einaga

Electrochemical detection of Se4+has been performed by anodic stripping voltammetry on a boron-doped diamond (BDD) electrode modified with gold nanoparticles deposited through chronocoulometry. This method is based on the affinity between the gold nanoparticles and Se0, while the BDD electrode is presented as an ideal material for metal modification due to its unique properties. The resulting anodic stripping voltammograms exhibited a clear peak at 0.9 V versus AgCl related to Se4+, and highly accurate (r2=0.99) calibration curves could be obtained for a selenium concentration range between 10 and 100 μg/L. The influence of Se deposition time and other metals dissolved in solution (Cu, Cd, Pb, Cr, and B) has been investigated as well, and it was found that the Se4+calibration curves remained unaltered. For all the experiments performed, a detection limit around 10 μg/L was achieved. The high accuracy and reproducibility of the results as well as the excellent stability of the electrode material proves the excellent capabilities of this system for selenium detection.


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