Application of trilobal capillary-channeled polymer (C-CP) fibers for reversed phase liquid chromatography and ESI-MS for the determination of proteins in different biological matrices

2019 ◽  
Vol 11 (30) ◽  
pp. 3800-3809 ◽  
Author(s):  
Katherine B. Youmans ◽  
Lei Wang ◽  
R. Kenneth Marcus
Keyword(s):  
Liquid Chromatography ◽  
Reversed Phase ◽  
Reversed Phase Liquid Chromatography ◽  
Biological Matrices ◽  
Esi Ms ◽  
P Protein ◽  
Phase Liquid

Protein mixtures in biological matrices can be directly analyzed by RP-LC on trilobal C-CP fiber columns coupled with ESI-MS.

Coupling of capillary-channeled polymer (C-CP) fibers for reversed phase liquid chromatography and ESI-MS for the determination of proteins in a urine matrix

2016 ◽  
Vol 8 (48) ◽  
pp. 8410-8419 ◽  
Author(s):  
Lei Wang ◽  
Marissa A. Pierson ◽  
R. Kenneth Marcus
Keyword(s):  
Mass Spectrometry ◽  
Liquid Chromatography ◽  
Reversed Phase ◽  
Ionization Mass ◽  
Reversed Phase Liquid Chromatography ◽  
Esi Ms ◽  
Detection Mode ◽  
Phase Liquid ◽  
Urine Matrix

Electrospray ionization mass spectrometry (ESI-MS) analysis provides a great deal of analytical information as a detection mode when coupled with liquid chromatography (LC) and capillary electrophoresis (CE) separations of proteins.

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