Two highly sensitive and selective coumarin-based fluorometric probes for the detection of ClO− and cell imaging

2019 ◽  
Vol 11 (14) ◽  
pp. 1916-1922 ◽  
Author(s):  
Lei Jin ◽  
Xiaoxue Tan ◽  
Cong Zhao ◽  
Qingming Wang
Keyword(s):  
Fluorescent Probes ◽  
Cell Imaging ◽  
Detection Limits ◽  
Oxidative Cleavage ◽  
Turn On ◽  
Efficient Detection ◽  
Highly Sensitive

Two new coumarin-based fluorescent probes were synthesized and successfully applied for the efficient detection of ClO− as turn-on fluorescence chemosensors by the oxidative cleavage of C–O and CN, the detection limits (LOD) for the two probes are 154 nM and 32 nM, respectively.

scholarly journals Cancer-Specific hNQO1-Responsive Biocompatible Naphthalimides Providing a Rapid Fluorescent Turn-On with an Enhanced Enzyme Affinity

Sensors ◽  
2019 ◽  
Vol 20 (1) ◽  
pp. 53 ◽  
Author(s):  
Sun Young Park ◽  
Eugeine Jung ◽  
Jong Seung Kim ◽  
Sung-Gil Chi ◽  
Min Hee Lee
Keyword(s):  
Cancer Cells ◽  
Fluorescent Probes ◽  
Therapeutic Agent ◽  
Cell Imaging ◽  
Physiological Condition ◽  
Live Cells ◽  
Strong Fluorescence ◽  
Turn On ◽  
Efficient Detection ◽  
Agent Development

Human NAD(P)H:quinone oxidoreductase 1 (hNQO1) is overexpressed in cancer cells and associated with the drug resistance factor of cancer. The objective of this work is the development of fluorescent probes for the efficient detection of hNQO1 activity in cancer cells, which can be employed for the cancer diagnosis and therapeutic agent development. Herein, we report naphthalimide-based fluorescent probes 1 and 2 that can detect hNQO1. For hNQO1 activity, the probes showed a significant fluorescence increase at 540 nm. In addition, probe 1, the naphthalimide containing a triphenylphosphonium salt, showed an enhanced enzyme efficiency and rapid detection under a physiological condition. The detection ability of probe 1 was superior to that of other previously reported probes. Moreover, probe 1 was less cytotoxic during the cancer cell imaging and readily provided a strong fluorescence in hNQO1-overexpressed cancer cells (A549). We proposed that probe 1 can be used to detect hNQO1 expression in live cells and it will be applied to develop the diagnosis and customized treatment of hNQO1-related disease.

Highly sensitive and selective turn-on fluorescent probes for Cu2+ based on rhodamine B

2015 ◽  
Vol 3 (26) ◽  
pp. 5261-5265 ◽  
Author(s):  
Ye Yuan ◽  
Shiguo Sun ◽  
Si Liu ◽  
Xinwei Song ◽  
Xiaojun Peng
Keyword(s):  
Fluorescent Probe ◽  
Fluorescent Probes ◽  
Rhodamine B ◽  
Turn On ◽  
Highly Sensitive

A new rhodamine B-based fluorescent probe RL for Cu2+ has been designed, synthesized, and characterized.

Boranil dye based “turn-on” fluorescent probes for detection of hydrogen peroxide and their cell imaging application

RSC Advances ◽  
2016 ◽  
Vol 6 (89) ◽  
pp. 85838-85843 ◽  
Author(s):  
Jayabalan Shanmugapriya ◽  
Kandasamy Rajaguru ◽  
Gandhi Sivaraman ◽  
Shanmugam Muthusubramanian ◽  
Nattamai Bhuvanesh
Keyword(s):  
Hydrogen Peroxide ◽  
Fluorescent Probes ◽  
Hela Cells ◽  
Cell Imaging ◽  
Physiological Conditions ◽  
Turn On ◽  
Imaging Application

The synthesis of boranil dye fluorescent probes for the detection of hydrogen peroxide has been described. The probes have been successfully applied for imaging of H2O2 in HeLa cells under physiological conditions.

scholarly journals Design of Turn‐On Near‐Infrared Fluorescent Probes for Highly Sensitive and Selective Monitoring of Biopolymers

2020 ◽  
Vol 59 (22) ◽  
pp. 8440-8444 ◽  
Author(s):  
Gerard T. Ducharme ◽  
Zane LaCasse ◽  
Tanya Sheth ◽  
Irina V. Nesterova ◽  
Evgueni E. Nesterov
Keyword(s):  
Fluorescent Probes ◽  
Near Infrared ◽  
Turn On ◽  
Highly Sensitive ◽  
Selective Monitoring

scholarly journals A chemosensor for Al3+ ions in aqueous ethanol media: photophysical and live cell imaging studies

RSC Advances ◽  
2016 ◽  
Vol 6 (22) ◽  
pp. 17995-18001 ◽  
Author(s):  
Nabanita Chatterjee ◽  
Shubhra Bikash Maity ◽  
Asmita Samadder ◽  
Puspal Mukherjee ◽  
Anisur Rahman Khuda-Bukhsh ◽  
...  
Keyword(s):  
Metal Ions ◽  
Live Cell Imaging ◽  
Cell Imaging ◽  
Aqueous Ethanol ◽  
Live Cell ◽  
Fluorescent Chemosensor ◽  
Selective Detection ◽  
Imaging Studies ◽  
Turn On ◽  
Highly Sensitive

A new rhodamine based highly sensitive “Turn-ON” fluorescent chemosensor L for the selective detection of Al3+ ion over other biologically competing metal ions in aqueous ethanol media.

Carbon nanodots prepared for cellular imaging and turn-on detection of glutathione

2016 ◽  
Vol 8 (23) ◽  
pp. 4736-4743 ◽  
Author(s):  
Depeng Kong ◽  
Fanyong Yan ◽  
Yunmei Luo ◽  
Yinyin Wang ◽  
Li Chen ◽  
...  
Keyword(s):  
Hydrothermal Method ◽  
Fluorescent Probes ◽  
Cellular Imaging ◽  
Carbon Nanodots ◽  
Intracellular Imaging ◽  
Turn On ◽  
Highly Sensitive ◽  
One Step

Carbon nanodots as fluorescent probes were synthesized through a one-step hydrothermal method. The carbon nanodots can be used not only for multicolor intracellular imaging but also for highly sensitive and selective turn-on detection of glutathione.

scholarly journals AIE-active Schiff base compounds as fluorescent probes for the highly sensitive and selective detection of Fe3+ ions

2020 ◽  
Vol 4 (5) ◽  
pp. 1471-1482 ◽  
Author(s):  
Jonnagaddala Harathi ◽  
Kathavarayan Thenmozhi
Keyword(s):  
Schiff Base ◽  
Fluorescent Probes ◽  
Photophysical Properties ◽  
Detection Limits ◽  
Association Constants ◽  
Selective Detection ◽  
High Association ◽  
Highly Sensitive ◽  
Enhanced Selectivity

AIE-active Schiff base compounds were synthesized and photophysical properties were investigated. The compounds exhibited prominent sensing behaviour towards Fe3+ ion with enhanced selectivity, high association constants and low detection limits.

Highly Sensitive and Fast Responsive Fluorescence Turn-On Chemodosimeter for Cu2+and Its Application in Live Cell Imaging

2008 ◽  
Vol 14 (23) ◽  
pp. 6892-6900 ◽  
Author(s):  
Mengxiao Yu ◽  
Mei Shi ◽  
Zhigang Chen ◽  
Fuyou Li ◽  
Xinxin Li ◽  
...  
Keyword(s):  
Live Cell Imaging ◽  
Cell Imaging ◽  
Live Cell ◽  
Turn On ◽  
Highly Sensitive ◽  
Fluorescence Turn On

scholarly journals Design of Turn‐On Near‐Infrared Fluorescent Probes for Highly Sensitive and Selective Monitoring of Biopolymers

2020 ◽  
Vol 132 (22) ◽  
pp. 8518-8522
Author(s):  
Gerard T. Ducharme ◽  
Zane LaCasse ◽  
Tanya Sheth ◽  
Irina V. Nesterova ◽  
Evgueni E. Nesterov
Keyword(s):  
Fluorescent Probes ◽  
Near Infrared ◽  
Turn On ◽  
Highly Sensitive ◽  
Selective Monitoring
Sign in / Sign up

Export Citation Format

Share Document