Multiple and sensitive SERS detection of cancer-related exosomes based on gold–silver bimetallic nanotrepangs

The Analyst ◽  
2020 ◽  
Vol 145 (7) ◽  
pp. 2795-2804 ◽  
Author(s):  
Cui-Fang Ning ◽  
Luying Wang ◽  
Ya-Fei Tian ◽  
Bin-Cheng Yin ◽  
Bang-Ce Ye
Keyword(s):  
Gold Silver ◽  
Sers Detection

Exosomes are endogenous vesicles of cells, and can be used as important biomarkers for cancers.

scholarly journals Microspectroscopic SERS detection of interleukin-6 with rationally designed gold/silver nanoshells

The Analyst ◽  
2013 ◽  
Vol 138 (6) ◽  
pp. 1764 ◽  
Author(s):  
Yuling Wang ◽  
Mohammad Salehi ◽  
Max Schütz ◽  
Katharina Rudi ◽  
Sebastian Schlücker
Keyword(s):  
Interleukin 6 ◽  
Gold Silver ◽  
Sers Detection ◽  
Silver Nanoshells

scholarly journals Glucose Detection of 4-Mercaptophenylboronic Acid-Immobilized Gold-Silver Core-Shell Assembled Silica Nanostructure by Surface Enhanced Raman Scattering

Nanomaterials ◽  
2021 ◽  
Vol 11 (4) ◽  
pp. 948
Author(s):  
Xuan-Hung Pham ◽  
Bomi Seong ◽  
Eunil Hahm ◽  
Kim-Hung Huynh ◽  
Yoon-Hee Kim ◽  
...  
Keyword(s):  
Raman Scattering ◽  
Calibration Curve ◽  
Core Shell ◽  
Glucose Detection ◽  
Gold Silver ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Sers Detection ◽  
Enhanced Raman Scattering ◽  
Silver Core

The importance of glucose in many biological processes continues to garner increasing research interest in the design and development of efficient biotechnology for the sensitive and selective monitoring of glucose. Here we report on a surface-enhanced Raman scattering (SERS) detection of 4-mercaptophenyl boronic acid (4-MPBA)-immobilized gold-silver core-shell assembled silica nanostructure (SiO2@Au@Ag@4-MPBA) for quantitative, selective detection of glucose in physiologically relevant concentration. This work confirmed that 4-MPBA converted to 4-mercaptophenol (4-MPhOH) in the presence of H2O2. In addition, a calibration curve for H2O2 detection of 0.3 µg/mL was successfully detected in the range of 1.0 to 1000 µg/mL. Moreover, the SiO2@Au@Ag@4-MPBA for glucose detection was developed in the presence of glucose oxidase (GOx) at the optimized condition of 100 µg/mL GOx with 1-h incubation time using 20 µg/mL SiO2@Au@Ag@4-MPBA and measuring Raman signal at 67 µg/mL SiO2@Au@Ag. At the optimized condition, the calibration curve in the range of 0.5 to 8.0 mM was successfully developed with an LOD of 0.15 mM. Based on those strategies, the SERS detection of glucose can be achieved in the physiologically relevant concentration range and opened a great promise to develop a SERS-based biosensor for a variety of biomedicine applications.

Multiplexed SERS Detection of Soluble Cancer Protein Biomarkers with Gold–Silver Alloy Nanoboxes and Nanoyeast Single-Chain Variable Fragments

2018 ◽  
Vol 90 (17) ◽  
pp. 10377-10384 ◽  
Author(s):  
Junrong Li ◽  
Jing Wang ◽  
Yadveer S. Grewal ◽  
Christopher B. Howard ◽  
Lyndon J. Raftery ◽  
...  
Keyword(s):  
Single Chain ◽  
Protein Biomarkers ◽  
Silver Alloy ◽  
Gold Silver ◽  
Sers Detection ◽  
Single Chain Variable Fragments

scholarly journals Multilayer Gold-Silver Bimetallic Nanostructures to Enhance SERS Detection of Drugs

Molecules ◽  
2020 ◽  
Vol 25 (15) ◽  
pp. 3405 ◽  
Author(s):  
Marta Gambucci ◽  
Elena Cambiotti ◽  
Paola Sassi ◽  
Loredana Latterini
Keyword(s):  
High Sensitivity ◽  
Accurate Information ◽  
Drug Detection ◽  
Drug Molecules ◽  
Gold Silver ◽  
Surface Enhanced Raman ◽  
Sers Detection ◽  
Molecular Specificity ◽  
Enhanced Raman Scattering ◽  
Bimetallic Nanostructures

Surface-enhanced Raman scattering (SERS) is a widely used technique for drug detection due to high sensitivity and molecular specificity. The applicability and selectivity of SERS in the detection of specific drug molecules can be improved by gathering information on the specific interactions occurring between the molecule and the metal surface. In this work, multilayer gold-silver bimetallic nanorods (Au@Ag@AuNRs) have been prepared and used as platforms for SERS detection of specific drugs (namely promethazine, piroxicam, furosemide and diclofenac). The analysis of SERS spectra provided accurate information on the molecular location upon binding and gave some insight into molecule-surface interactions and selectivity in drug detection through SERS.

scholarly journals Tailoring gold and silver colloidal bimetallic nanoalloys towards SERS detection of rhodamine 6G

RSC Advances ◽  
2017 ◽  
Vol 7 (26) ◽  
pp. 15944-15951 ◽  
Author(s):  
A. V. Girão ◽  
P. C. Pinheiro ◽  
M. Ferro ◽  
T. Trindade
Keyword(s):  
Rhodamine 6G ◽  
Bimetallic Alloys ◽  
Gold Silver ◽  
Sers Detection ◽  
Sers Sensing

Nanoparticles of gold, silver and their bimetallic alloys were tailored for SERS sensing towards trace amounts of rhodamine 6G.

Metallic Nanoparticle Synthesis by Green Chemistry

2018 ◽  
Vol 11 (6) ◽  
pp. 4287-4294
Author(s):  
Anikate Sood ◽  
Shweta Agarwal
Keyword(s):  
Green Chemistry ◽  
Green Synthesis ◽  
Biomedical Research ◽  
Metallic Nanoparticles ◽  
Nanoparticle Synthesis ◽  
Synthesis Methods ◽  
Metallic Nanoparticle ◽  
Medical Field ◽  
Advantages And Disadvantages ◽  
Gold Silver

Nanotechnology is the most sought field in biomedical research. Metallic nanoparticles have wide applications in the medical field and have gained the attention of various researchers for advanced research for their application in pharmaceutical field. A variety of metallic nanoparticles like gold, silver, platinum, palladium, copper and zinc have been developed so far. There are different methods to synthesize metallic nanoparticles like chemical, physical, and green synthesis methods. Chemical and physical approaches suffer from certain drawbacks whereas green synthesis is emerging as a nontoxic and eco-friendly approach in production of metallic nanoparticles. Green synthesis is further divided into different approaches like synthesis via bacteria, fungi, algae, and plants. These approaches have their own advantages and disadvantages. In this article, we have described various metallic nanoparticles, different modes of green synthesis and brief description about different metabolites present in plant that act as reducing agents in green synthesis of metallic nanoparticles. 

Latvju dainu atbalsis Veltas Sniķeres lirikā

2020 ◽  
pp. 124-134
Author(s):  
Sintija Kampāne-Štelmahere
Keyword(s):  
Indian Philosophy ◽  
First Language ◽  
Folk Songs ◽  
Folk Song ◽  
Ethical Values ◽  
Exile Literature ◽  
Gold Silver ◽  
Research Objects ◽  
Literary Methods ◽  
Prehistoric Time

The research “Echoes of Latvian Dainas in the Lyrics of Velta Sniķere” examines motifs and fragments of Latvian folk songs in the poetry by Sniķere. Several poems that directly reveal the montage of folk songs are selected as research objects. Linguistic, semantic, hermeneutical and historical as well as literary methods were used in poetry analysis. The research emphasizes the importance of Latvian folklore in the process of Latvian exile literature, the genesis of modern lyrics, and the philosophical conception of the poet. Latvian folk songs in the lyrics of Sniķere are mainly perceived as a source of ancient knowledge and as a path to the Indo-European first language, prehistoric time, which is understood only in a poetic state. Often, the montage of Latvian folk songs or their fragments in the lyrics of Sniķere is revealed as a reflexive reverence that creates a semantic fracture and opposition between profane and sacred view. The insertion of a song in the poem alters the rhythmic and phonetic sound: a free and sometimes dissonant article is replaced by a harmonic trochee, while an internationalism saturated language is replaced by a simple, phonetically effective language composed of alliterations and assonances. The montage of folk songs in a poem is justified by the necessity to restore the Latvian identity in exile, to restore the memory of ancient, mythical knowledge, to represent the understanding of beauty and other moral-ethical values and to show the thought activity. Common mythical images in the lyrics of Sniķere are snake, wind, gold, silver, stone etc. The Latvian folk song symbolism and lifestyle of the poet are organically synthesized with the insights of Indian philosophy.

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