Electrospun nanofibers: a promising horizon toward the detection and treatment of cancer

The Analyst ◽  
2020 ◽  
Vol 145 (8) ◽  
pp. 2854-2872 ◽  
Author(s):  
Sahar Asghari ◽  
Zahra Rezaei ◽  
Matin Mahmoudifard
Keyword(s):  
Cancer Detection ◽  
Potential Application ◽  
Electrospun Nanofibers ◽  
Nanofibrous Membranes

Potential application of electrospun nanofibrous membranes in cancer detection and treatment.

scholarly journals Micropatterning MoS2/Polyamide Electrospun Nanofibrous Membranes Using Femtosecond Laser Pulses

Photonics ◽  
2019 ◽  
Vol 6 (1) ◽  
pp. 3 ◽  
Author(s):  
Kelly T. Paula ◽  
Luiza A. Mercante ◽  
Rodrigo Schneider ◽  
Daniel S. Correa ◽  
Cleber R. Mendonca
Keyword(s):  
Laser Ablation ◽  
Composite Nanofibers ◽  
Electrospun Nanofibers ◽  
Scanning Speed ◽  
Laser Pulses ◽  
Femtosecond Laser Pulses ◽  
Spectroscopic Techniques ◽  
Fs Laser ◽  
Nanofibrous Membranes ◽  
Scale Control

The capability of modifying and patterning the surface of polymer and composite materials is of high significance for various biomedical and electronics applications. For example, the use of femtosecond (fs) laser ablation for micropatterning electrospun nanofiber scaffolds can be successfully employed to fabricate complex polymeric biomedical devices, including scaffolds. Here we investigated fs-laser ablation as a flexible and convenient method for micropatterning polyamide (PA6) electrospun nanofibers that were modified with molybdenum disulfide (MoS2). We studied the influence of the laser pulse energy and scanning speed on the topography of electrospun composite nanofibers, as well as the irradiated areas via scanning electron microscopy and spectroscopic techniques. The results showed that using the optimal fs-laser parameters, micropores were formed on the electrospun nanofibrous membranes with size scale control, while the nature of the nanofibers was preserved. MoS2-modified PA6 nanofibrous membranes showed good photoluminescence properties, even after fs-laser microstructuring. The results presented here demonstrated potential application in optoelectronic devices. In addition, the application of this technique has a great deal of potential in the biomedical field, such as in tissue engineering.

Biocompatible core–shell electrospun nanofibers as potential application for chemotherapy against ovary cancer

2014 ◽  
Vol 41 ◽  
pp. 217-223 ◽  
Author(s):  
Eryun Yan ◽  
Yingmei Fan ◽  
Zhiyao Sun ◽  
Jianwei Gao ◽  
Xiaoyuan Hao ◽  
...  
Keyword(s):  
Potential Application ◽  
Electrospun Nanofibers ◽  
Core Shell ◽  
Ovary Cancer

A general strategy for fabricating flexible magnetic silica nanofibrous membranes with multifunctionality

2015 ◽  
Vol 51 (63) ◽  
pp. 12521-12524 ◽  
Author(s):  
Yang Si ◽  
Chengcheng Yan ◽  
Feifei Hong ◽  
Jianyong Yu ◽  
Bin Ding
Keyword(s):  
Electrospun Nanofibers ◽  
General Strategy ◽  
Hierarchical Porous ◽  
Magnetic Silica ◽  
Nanofibrous Membranes

Flexible, magnetic, and hierarchical porous NiFe2O4@SiO2 nanofibrous membranes with multifunctionality were prepared by combining the gelatin method with electrospun nanofibers.

scholarly journals Arced Multi-Nozzle Electrospinning Spinneret for High-Throughput Production of Nanofibers

Micromachines ◽  
2019 ◽  
Vol 11 (1) ◽  
pp. 27 ◽  
Author(s):  
Jiaxin Jiang ◽  
Gaofeng Zheng ◽  
Xiang Wang ◽  
Wenwang Li ◽  
Guoyi Kang ◽  
...  
Keyword(s):  
High Throughput ◽  
Applied Voltage ◽  
Production Efficiency ◽  
Electrospun Nanofibers ◽  
Average Diameter ◽  
Electrical Field ◽  
Multiple Jets ◽  
Nanofibrous Membranes ◽  
Stretching Effect ◽  
Electrical Interference

The stable and continuous ejection of multiple jets with high densities is the key to the application of electrospinning technology. An arced multi-nozzle spinneret was designed to increase the production efficiency of electrospinning. The distribution of the electrical field was simulated to optimize the nozzles’ distribution of the spinneret. When the nozzles were arranged in an arc array, a relatively uniform electrical field could be obtained, which was beneficial for the weakening of electrical interference among the nozzles. Under the optimized electrical field, multiple jets from each nozzle could be ejected in a stable and continuous way. With the increase of the applied voltage, the electrical stretching force became larger, and there were fewer bonding structures. The average diameter of the electrospun nanofibers decreased with the increase of the applied voltage. When the distance between the inner nozzle and the collector increased, the charged jets suffered a larger stretching effect, resulting in the decrease of the average diameter of the electrospun nanofibers. The electrospinning current increased with the applied voltage and decreased with the distance between the inner nozzle and the collector, which is an important aspect for the monitoring of electrospinning jets. This work provides an effective way to promote the production efficiency of electrospun nanofibrous membranes.

Quaternary ammonium salt–modified polyacrylonitrile/polycaprolactone electrospun nanofibers with enhanced antibacterial properties

2021 ◽  
pp. 004051752199718
Author(s):  
Hongnan Zhang ◽  
Tingting Zhang ◽  
Qiaohua Qiu ◽  
Xiaohong Qin
Keyword(s):  
Antibacterial Properties ◽  
Electrospun Nanofibers ◽  
Tensile Tests ◽  
Nanofibrous Membrane ◽  
E Coli ◽  
Small Pore Size ◽  
Small Pore ◽  
Inhibition Zones ◽  
Nanofibrous Membranes ◽  
And Staphylococcus Aureus

In this experiment, octadecyltrimethylammonium chloride (STAC), a cationic antibacterial agent, was designed to modify hydrolyzed polyacrylonitrile (PAN) through tight electrostatic attraction. Then, the modified PAN was successfully electrospun with polycaprolactone (PCL) to obtain PCL/PAN-STAC nanofibrous membranes with enhanced mechanical properties. The modified PAN was characterized by Fourier transform infrared spectroscopy, thermogravimetric analysis and elemental analysis. The morphological, mechanical and antibacterial properties of nanofibrous membranes were investigated. The blended nanofibrous membrane presented a uniform and stable structure with small pore size. Tensile tests indicated that the mechanical property of PCL/PAN-STAC nanofibrous membrane was obviously enhanced by blending. Disk diffusion tests showed that the inhibition zones of PCL/PAN-STAC against Escherichia coli and Staphylococcus aureus were 7.56 ± 0.05 mm and 15.37 ± 0.34 mm, respectively. Shaking method indicated that the antibacterial activity against E. coli was as high as 96.20 ± 0.89% when the use of PCL/PAN-STAC reached 9 mg. Therefore, this antibacterial nanofibrous membrane is very favorable for applications such as protective filtration masks and wound dressing.

scholarly journals Electrospun nanofibers of polyCD/PMAA polymers and their potential application as drug delivery system

2015 ◽  
Vol 54 ◽  
pp. 252-261 ◽  
Author(s):  
Michele F. Oliveira ◽  
Diego Suarez ◽  
Júlio Cézar Barbosa Rocha ◽  
Alvaro Vianna Novaes de Carvalho Teixeira ◽  
Maria E. Cortés ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Drug Delivery System ◽  
Delivery System ◽  
Potential Application ◽  
Electrospun Nanofibers

Surface-engineered quantum dots/electrospun nanofibers as a networked fluorescence aptasensing platform toward biomarkers

Nanoscale ◽  
2017 ◽  
Vol 9 (43) ◽  
pp. 17020-17028 ◽  
Author(s):  
Tong Yang ◽  
Peng Hou ◽  
Lin Ling Zheng ◽  
Lei Zhan ◽  
Peng Fei Gao ◽  
...  
Keyword(s):  
Quantum Dots ◽  
Electrospun Nanofibers ◽  
Nanofibrous Membranes

QD-lit and networked electrospun nanofibrous membranes were employed as an aptasensor to facilely, sensitively and specifically detect biomarkers based on NSET between QDs and AuNPs.

Sign in / Sign up

Export Citation Format

Share Document