Retracted Article: Microelectrochemical cell arrays for whole-cell currents recording through ion channel proteins based on trans-electroporation approach

The Analyst ◽  
2020 ◽  
Vol 145 (1) ◽  
pp. 197-205 ◽  
Author(s):  
Tianyang Zheng ◽  
Gerhard Baaken ◽  
Jan C. Behrends ◽  
Jürgen Rühe
Keyword(s):  
Cell Membrane ◽  
Ion Channel ◽  
Biological Cell ◽  
Whole Cell ◽  
Channel Proteins ◽  
Retracted Article ◽  
Cell Arrays ◽  
Ion Channel Proteins

A novel chip based method is able to record the whole-cell currents through biological cell membrane with high electrostability.

scholarly journals Retraction: Microelectrochemical cell arrays for whole-cell currents recording through ion channel proteins based on trans-electroporation approach

The Analyst ◽  
2020 ◽  
Vol 145 (5) ◽  
pp. 1961-1961
Author(s):  
Tianyang Zheng ◽  
Gerhard Baaken ◽  
Jan C. Behrends ◽  
Jürgen Rühe
Keyword(s):  
Ion Channel ◽  
Whole Cell ◽  
Channel Proteins ◽  
Cell Arrays ◽  
Ion Channel Proteins

Retraction of ‘Microelectrochemical cell arrays for whole-cell currents recording through ion channel proteins based on trans-electroporation approach’ by Tianyang Zheng et al., Analyst, 2020, 145, 197–205.

scholarly journals Correction: Microelectrochemical cell arrays for whole-cell currents recording through ion channel proteins based on trans-electroporation approach

The Analyst ◽  
2020 ◽  
Vol 145 (4) ◽  
pp. 1532-1532
Author(s):  
Tianyang Zheng ◽  
Gerhard Baaken ◽  
Jan C. Behrends ◽  
Jürgen Rühe
Keyword(s):  
Ion Channel ◽  
Whole Cell ◽  
Channel Proteins ◽  
Cell Arrays ◽  
Ion Channel Proteins

Correction for ‘Microelectrochemical cell arrays for whole-cell currents recording through ion channel proteins based on trans-electroporation approach’ by Tianyang Zheng, et al., Analyst, 2020, DOI: 10.1039/c9an01737b.

scholarly journals Measuring the Spatial Arrangement of Nmj-Nachr ion Channel Proteins in the Cell Membrane

2011 ◽  
Vol 100 (3) ◽  
pp. 348a
Author(s):  
Hannah DeBerg ◽  
Nir Friedman ◽  
Cong T. Nguyen ◽  
Paul Simonson ◽  
Paul Selvin
Keyword(s):  
Cell Membrane ◽  
Ion Channel ◽  
Spatial Arrangement ◽  
Channel Proteins ◽  
Ion Channel Proteins

scholarly journals Inhibition of heart calcium and chloride currents by sodium iodide. Specific attenuation in cAMP-dependent protein kinase-mediated regulation.

1992 ◽  
Vol 100 (5) ◽  
pp. 847-865 ◽  
Author(s):  
K B Walsh ◽  
K J Long
Keyword(s):  
Protein Kinase ◽  
Ion Channel ◽  
External Solution ◽  
Calcium Currents ◽  
Dependent Protein Kinase ◽  
Whole Cell ◽  
Channel Proteins ◽  
Camp Dependent Protein Kinase ◽  
Dependent Protein ◽  
Ion Channel Proteins

The enzymes cAMP-dependent protein kinase (PKA) and protein kinase C (PKC) regulate the activity of cardiac ion channel proteins. In this study the whole-cell arrangement of the patch clamp technique was used to examine the effect of NaI on PKA-stimulated Cl- and Ca2+ channels in isolated guinea pig ventricular myocytes. Cl- currents (ICl) activated either by the beta-adrenergic agonist isoproterenol or the membrane-soluble cAMP analogue, 8-chlorphenylthio (8-CPT) cAMP, were greatly reduced in amplitude after substitution of an external solution containing 140 mM NaCl with a solution containing 140 mM NaI. This reduction was accompanied by a shift of -7 mV in the reversal potential (Erev) for ICl and could be reversed upon return to the NaCl external solution. Inhibition of ICl by NaI occurred in a concentration-dependent manner and was more pronounced for inward ICl (IC50 = 19 mM at -60 mV) than for outward ICl (IC50 = 60 mM at +60 mV). In contrast to ICl activated by PKA, ICl activated by PKC was slightly augmented in the presence of NaI and the Erev was found to shift by -15 mV. Based on these data, the relative permeability of I- to Cl- (PI/PCl) for this channel was calculated to be 1.79. NaI produced no change in the amplitude of inward calcium currents (ICa) recorded under basal conditions, but strongly inhibited ICa augmented by isoproterenol and 8-CPT cAMP, and during dialysis of cells with the catalytic subunit of PKA (CS). The in vitro incorporation of [gamma-32P]ATP into histone IIA and Kemptide, measured in the presence of PKA and cAMP, was not significantly different in assay mixtures containing salts of Cl- and I-. However, the ability of isoproterenol to augment basal ICa in whole-cell experiments was attenuated when experiments were carried out entirely in NaI external solution. Thus, the reduction in ICl and ICa observed in this study may result from a direct effect of I- on the phosphorylation/dephosphorylation of cardiac ion channel proteins or associated regulatory proteins.

ChemInform Abstract: Synthetic Peptides as Models for Ion Channel Proteins

ChemInform ◽  
2010 ◽  
Vol 24 (32) ◽  
pp. no-no
Author(s):  
K. S. AKERFELDT ◽  
J. D. LEAR ◽  
Z. R. WASSERMAN ◽  
L. A. CHUNG ◽  
W. F. DEGRADO
Keyword(s):  
Ion Channel ◽  
Synthetic Peptides ◽  
Channel Proteins ◽  
Ion Channel Proteins

Activity of single ion channel proteins detected with a planar microstructure

2002 ◽  
Vol 81 (25) ◽  
pp. 4865-4867 ◽  
Author(s):  
Niels Fertig ◽  
Michèle Klau ◽  
Michael George ◽  
Robert H. Blick ◽  
Jan C. Behrends
Keyword(s):  
Ion Channel ◽  
Channel Proteins ◽  
Ion Channel Proteins

scholarly journals Involvement of TRPV3 and TRPM8 ion channel proteins in induction of mammalian cold-inducible proteins

2018 ◽  
Vol 495 (1) ◽  
pp. 935-940 ◽  
Author(s):  
Takanori Fujita ◽  
Yu Liu ◽  
Hiroaki Higashitsuji ◽  
Katsuhiko Itoh ◽  
Koji Shibasaki ◽  
...  
Keyword(s):  
Ion Channel ◽  
Channel Proteins ◽  
Ion Channel Proteins
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