scholarly journals Label-free detection of nosocomial bacteria using a nanophotonic interferometric biosensor

The Analyst ◽  
2020 ◽  
Vol 145 (2) ◽  
pp. 497-506 ◽  
Author(s):  
Jesús Maldonado ◽  
M.-Carmen Estévez ◽  
Adrián Fernández-Gavela ◽  
Juan José González-López ◽  
Ana Belén González-Guerrero ◽  
...  
Keyword(s):  
Sensitive Detection ◽  
Label Free ◽  
Label Free Detection ◽  
Interferometric Biosensor

Two methodologies using a BiMW biosensor have been developed for the fast, sensitive detection of P. aeruginosa and MRSA bacteria.

Graphene oxide amplified fluorescence anisotropy for label-free detection of potassium ion

The Analyst ◽  
2015 ◽  
Vol 140 (1) ◽  
pp. 353-357 ◽  
Author(s):  
Shu Jun Zhen ◽  
Yan Yu ◽  
Chun Mei Li ◽  
Cheng Zhi Huang
Keyword(s):  
Graphene Oxide ◽  
Fluorescence Anisotropy ◽  
Potassium Ion ◽  
Sensitive Detection ◽  
Label Free ◽  
Label Free Detection

A label-free fluorescence anisotropy method for the sensitive detection of potassium ion, by using graphene oxide as enhancer, was established.

scholarly journals Label-free detection of bovine serum albumin based on an in-fiber Mach-Zehnder interferometric biosensor

2017 ◽  
Vol 25 (15) ◽  
pp. 17105 ◽  
Author(s):  
Zhengyong Li ◽  
Changrui Liao ◽  
Danni Chen ◽  
Jun Song ◽  
Wei Jin ◽  
...  
Keyword(s):  
Bovine Serum Albumin ◽  
Serum Albumin ◽  
Bovine Serum ◽  
Label Free ◽  
Label Free Detection ◽  
Interferometric Biosensor

Gold nanoparticle integrated artificial nanochannels for label-free detection of peroxynitrite

2021 ◽  
Author(s):  
Jing Wu ◽  
Xing Wang ◽  
Lei Ge ◽  
Rui Lv ◽  
Fan Zhang ◽  
...  
Keyword(s):  
Small Molecules ◽  
Gold Nanoparticle ◽  
Sensitive Detection ◽  
Label Free ◽  
Highly Sensitive ◽  
Label Free Detection ◽  
Highly Sensitive Detection

A label-free method for rapid and highly sensitive detection of ONOO− was proposed by employing ABEI@AuNPs integrated nanochannels. This work paves a new way to develop a versatile platform for the detection of different biological small molecules.

Fluorescein-based ionic liquid sensor for label-free detection of serum albumins

RSC Advances ◽  
2014 ◽  
Vol 4 (34) ◽  
pp. 17533-17540 ◽  
Author(s):  
Waduge Indika S. Galpothdeniya ◽  
Susmita Das ◽  
Sergio L. De Rooy ◽  
Bishnu P. Regmi ◽  
Suzana Hamdan ◽  
...  
Keyword(s):  
Ionic Liquid ◽  
Fluorescent Probe ◽  
Room Temperature ◽  
Room Temperature Ionic Liquid ◽  
Sensitive Detection ◽  
Label Free ◽  
Serum Albumins ◽  
Label Free Detection

Fluorescein-based room temperature ionic liquid as a fluorescent probe for highly selective and sensitive detection of serum albumins.

scholarly journals Development of Highly Sensitive Immunosensor for Detection of Staphylococcus aureus Based on AuPdPt Trimetallic Nanoparticles Functionalized Nanocomposite

Micromachines ◽  
2021 ◽  
Vol 12 (4) ◽  
pp. 446
Author(s):  
En Han ◽  
Yun Zhang ◽  
Jianrong Cai ◽  
Xinai Zhang
Keyword(s):  
Staphylococcus Aureus ◽  
Catalytic Performance ◽  
High Specific Surface Area ◽  
Electrochemical Immunosensor ◽  
Sensitive Detection ◽  
Label Free ◽  
Catalytic Current ◽  
Highly Sensitive ◽  
Label Free Detection ◽  
Growth Method

The rapid and sensitive detection of Staphylococcus aureus (S. aureus) is essential to ensure food safety and protect humans from foodborne diseases. In this study, a sensitive and facile electrochemical immunosensor using AuPdPt trimetallic nanoparticles functionalized multi-walled carbon nanotubes (MWCNTs-AuPdPt) as the signal amplification platform was designed for the label-free detection of S. aureus. The nanocomposite of MWCNTs-AuPdPt was prepared by an in situ growth method of loading AuPdPt trimetallic nanoparticles on the surface of MWCNTs. The synthesized MWCNTs-AuPdPt featured good conductivity and superior catalytic performance for hydrogen peroxide. The nanocomposite of MWCNTs-AuPdPt with good biocompatibility and high specific surface area was further functionalized by anti-S. aureus antibodies. The immobilized antibodies could efficiently capture S. aureus to the modified electrode by an immune reaction, which resulted in the change of catalytic current intensity to realize the sensitive detection of S. aureus. The designed immunosensor could detect S. aureus in a linear range from 1.1 × 102 to 1.1 × 107 CFU mL−1 with a low detection limit of 39 CFU mL−1. Additionally, the proposed immunosensor was successfully applied to determine S. aureus in actual samples with acceptable results. This strategy provided a promising platform for highly sensitive determination of S. aureus and other pathogens in food products.

Aptamer-mediated rolling circle amplification for label-free and sensitive detection of histone acetyltransferase activity

2021 ◽  
Vol 57 (16) ◽  
pp. 2041-2044
Author(s):  
Su Jiang ◽  
Meng Liu ◽  
Wei Tantai ◽  
Qinfeng Xu ◽  
Xiaoran Zou ◽  
...  
Keyword(s):  
Histone Modification ◽  
Histone Acetyltransferase ◽  
Rolling Circle Amplification ◽  
Sensitive Detection ◽  
Label Free ◽  
Site Specific ◽  
Rolling Circle ◽  
Acetyltransferase Activity ◽  
Label Free Detection ◽  
Histone Acetyltransferase Activity

An aptamer-mediated histone modification site-specific rolling circle amplification is developed for label-free detection of histone-modifying enzyme at the femtomolar level.

scholarly journals Label-free sensitive detection of influenza virus using PZT discs with a synthetic sialylglycopolymer receptor layer

2019 ◽  
Vol 6 (9) ◽  
pp. 190255 ◽  
Author(s):  
Alexander S. Erofeev ◽  
Petr V. Gorelkin ◽  
Dmitry V. Kolesov ◽  
Gleb A. Kiselev ◽  
Evgeniy V. Dubrovin ◽  
...  
Keyword(s):  
Lead Zirconate Titanate ◽  
Influenza A ◽  
High Sensitivity ◽  
Influenza Viruses ◽  
Radial Mode ◽  
Sensitive Detection ◽  
Label Free ◽  
Influenza A Viruses ◽  
Label Free Detection ◽  
Receptor Layer

We describe rapid, label-free detection of Influenza A viruses using the first radial mode of oscillations of lead zirconate titanate (PZT) piezoelectric discs with a 2 mm radius and 100 µm thickness fabricated from a piezoelectric membrane. The discs are modified with a synthetic sialylglycopolymer receptor layer, and the coated discs are inserted in a flowing virus suspension. Label-free detection of the virus is achieved by monitoring the disc radial mode resonance frequency shift. Piezo transducers with sialylglycopolymer sensor layers exhibited a long lifetime, a high sensitivity and the possibility of regeneration. We demonstrate positive, label-free detection of Influenza A viruses at concentrations below 10 5 virus particles per millilitre. We show that label-free, selective, sensitive detection of influenza viruses by home appliances is possible in principle.

Interferometric biosensor based on planar optical waveguide sensor chips for label-free detection of surface bound bioreactions

2007 ◽  
Vol 22 (11) ◽  
pp. 2591-2597 ◽  
Author(s):  
Katrin Schmitt ◽  
Bernd Schirmer ◽  
Christian Hoffmann ◽  
Albrecht Brandenburg ◽  
Patrick Meyrueis
Keyword(s):  
Optical Waveguide ◽  
Label Free ◽  
Planar Optical Waveguide ◽  
Label Free Detection ◽  
Interferometric Biosensor ◽  
Waveguide Sensor

scholarly journals Design of an aptamer – based fluorescence displacement biosensor for selective and sensitive detection of kanamycin in aqueous samples

RSC Advances ◽  
2017 ◽  
Vol 7 (61) ◽  
pp. 38512-38518 ◽  
Author(s):  
Long Ma ◽  
Nana Sun ◽  
Chunhao Tu ◽  
Qian Zhang ◽  
Aipo Diao
Keyword(s):  
Detection Method ◽  
Sensitive Detection ◽  
Label Free ◽  
Aqueous Samples ◽  
Label Free Detection

A label-free detection method for kanamycin A using an aptamer-based displacement biosensor has been developed.

Target-initiated synthesis of fluorescent copper nanoparticles for the sensitive and label-free detection of bleomycin

Nanoscale ◽  
2018 ◽  
Vol 10 (23) ◽  
pp. 11134-11142 ◽  
Author(s):  
Dandan Zhang ◽  
Juan Hu ◽  
Xiao-yun Yang ◽  
Yanxia Wu ◽  
Wenmei Su ◽  
...  
Keyword(s):  
Copper Nanoparticles ◽  
Sensitive Detection ◽  
Label Free ◽  
Label Free Detection

We developed a label-free method for the sensitive detection of bleomycin on the basis of the target-initiated synthesis of fluorescent copper nanoparticles.

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