Accurate determination of the layer thickness of a multilayer polymer film by non-invasive multivariate confocal Raman microscopy

The Analyst ◽  
2019 ◽  
Vol 144 (18) ◽  
pp. 5600-5607 ◽  
Author(s):  
Mingyi Zou ◽  
Bastian Barton ◽  
Guru Geertz ◽  
Robert Brüll
Keyword(s):  
Spectral Decomposition ◽  
Layer Structure ◽  
Accurate Determination ◽  
Depth Profiling ◽  
Multilayer Films ◽  
Confocal Raman Microscopy ◽  
Non Invasive ◽  
Composition Determination ◽  
Confocal Raman

We present a confocal Raman depth profiling technique combined with multivariate spectral decomposition. The method allows for non-invasive layer structure and chemical composition determination on polymer multilayer films with micrometer accuracy.

Clearance and Non-Invasive Determination of the Hepatic Extraction of Indocyanine Green in Baboons and Man

1983 ◽  
Vol 64 (2) ◽  
pp. 207-212 ◽  
Author(s):  
S. L. Grainger ◽  
P. W. N. Keeling ◽  
I. M. H. Brown ◽  
J. H. Marigold ◽  
R. P. H. Thompson
Keyword(s):  
Indocyanine Green ◽  
Accurate Determination ◽  
Liver Blood Flow ◽  
Compartment Model ◽  
Hepatic Extraction ◽  
Non Invasive ◽  
Two Compartment Model ◽  
Hepatic Extraction Ratio ◽  
Plasma Disappearance Curve

1. The disposition of an intravenous bolus of indocyanine green (ICG) has been studied in healthy man and baboons using a novel analysis of a two compartment pharmacokinetic model. 2. This analysis enabled the hepatic extraction ratio (ER) of dye to be determined solely from the plasma disappearance curve, and the ER determined did not differ from that measured by hepatic vein catheterization. 3. When compared with clearance measured at steady state, the two compartment model gave a significantly more accurate determination of plasma clearance than did the conventional one compartment model. 4. It is concluded that, in health, liver blood flow may be calculated accurately and noninvasively after a single intravenous injection of ICG.

Single Layer Graphene for Estimation of Axial Spatial Resolution in Confocal Raman Microscopy Depth Profiling

2018 ◽  
Vol 91 (1) ◽  
pp. 1049-1055 ◽  
Author(s):  
Carol Korzeniewski ◽  
Jay P. Kitt ◽  
Saheed Bukola ◽  
Stephen E. Creager ◽  
Shelley D. Minteer ◽  
...  
Keyword(s):  
Spatial Resolution ◽  
Depth Profiling ◽  
Single Layer ◽  
Raman Microscopy ◽  
Single Layer Graphene ◽  
Confocal Raman Microscopy ◽  
Layer Graphene ◽  
Confocal Raman

scholarly journals In vivo Tracking of DNA for Precise Determination of the Stratum Corneum Thickness and Superficial Microbiome Using Confocal Raman Microscopy

2019 ◽  
Vol 33 (1) ◽  
pp. 30-37 ◽  
Author(s):  
Jin Song Ri ◽  
Se Hyok Choe ◽  
Johannes Schleusener ◽  
Jürgen Lademann ◽  
Chun Sik Choe ◽  
...  
Keyword(s):  
Stratum Corneum ◽  
Precise Determination ◽  
Raman Microscopy ◽  
Confocal Raman Microscopy ◽  
Confocal Raman
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