Improvement of biosensor accuracy using an interference index detection system to minimize the interference effects caused by icterus and hemolysis in blood samples

The Analyst ◽  
2019 ◽  
Vol 144 (17) ◽  
pp. 5223-5231 ◽  
Author(s):  
Sungha Park
Keyword(s):  
Measurement Accuracy ◽  
Detection System ◽  
Clinical Applications ◽  
Optical Characteristics ◽  
Interference Effects ◽  
Blood Samples

An IID system was developed to improve the measurement accuracy of biosensors used in clinical applications by removing the optical characteristics of interference caused by icterus and hemolysis in blood samples.

Assessment of erythrocyte aggregation in whole blood samples by light backscattering: clinical applications

1999 ◽  
Author(s):  
Alexander V. Priezzhev ◽  
Nikolai N. Firsov ◽  
Marina G. Vyshlova ◽  
Juergen Lademann ◽  
Heike Richter ◽  
...  
Keyword(s):  
Whole Blood ◽  
Clinical Applications ◽  
Erythrocyte Aggregation ◽  
Blood Samples ◽  
Whole Blood Samples

Device and Method for Large Size Aspheric Measurement

2010 ◽  
Vol 97-101 ◽  
pp. 4324-4327
Author(s):  
Yong Lu Zhu ◽  
Yin Biao Guo ◽  
Xiao Long Ke ◽  
Lu Shuang Chen
Keyword(s):  
Control System ◽  
Measurement System ◽  
Measurement Method ◽  
Measurement Accuracy ◽  
Detection System ◽  
Experimental Results ◽  
Aspheric Surface ◽  
Large Size ◽  
And Control

In this paper, the necessary instrument and control system called the “Large Size Four-axis Measurement System” which used for measuring large size aspheric surface have been designed and established. Then the development of semi-meridian measurement method on basis of large size four-axis detection system has been reported. The measurement paths were planed and the measurement program was performed on the IPC. The method can significantly reduced the align error caused by the aspheric center which is not coincidence with the rotation platform center. With the measurement system, an aspheric surface was successfully measured; whose radius of semi-meridian was 55 mm. The experimental results show that the developed methods are simple and rapid. The measurement accuracy can satisfy requirement of aspheric surface.

Method of Attitude Measurement Based on the Geomagnetic and Gyroscope

2013 ◽  
Vol 336-338 ◽  
pp. 180-184 ◽  
Author(s):  
Li Long ◽  
He Zhang
Keyword(s):  
Pitch Angle ◽  
Measurement Accuracy ◽  
Performance Test ◽  
Detection System ◽  
Roll Angle ◽  
Angle Error ◽  
Blind Area ◽  
Trajectory Correction ◽  
Yaw Angle ◽  
Attitude Detection

The trajectory correction capability of the Simple guided munitions is directly affected by measurement accuracy of attitude angle. A gesture detection method based on geomagnetic gyro combination is proposed in this paper in order to detect the projectile flight attitude, The yaw angle of the projectile is solved by using runge-kutta algorithm with angle information of MEMS gyro. Then roll angle and pitch angle of the projectile is solved by magnetic field component of the three-axis magnetic sensor. Finally, the whole attitude detection system is installed in three-axis non-magnetic turntable to have a performance test. Experimental results show that the attitude solution results error is small. Nearby blind area, the roll angle error reduced to 5° and the pitch angle error reduced to 4°. In other locations, the roll angle error reduced to 2° and the pitch angle error reduce to 1°. The measurement accuracy increased nearly tenfold, can satisfy the trajectory correction demand of simple guidance ammunition.

scholarly journals Development of Contactless Sand Production Test Instrument

2017 ◽  
Vol 10 (1) ◽  
pp. 1-11
Author(s):  
Huiqin Jia ◽  
Ruirong Dang
Keyword(s):  
Oil Recovery ◽  
Measurement Accuracy ◽  
Detection System ◽  
Ultrasonic Method ◽  
Production Test ◽  
Oil Well ◽  
Sand Content ◽  
Oil Sand ◽  
Sand Production ◽  
Computation Model

Background:Sand production is an important factor affecting reservoir exploitation. Excessive sand production affects the oil well life, causes the damage to the oil recovery device and brings serious hidden danger in the process of safety production.Objective:This paper presents a sand content computation model for the crude oil, which uses the power of sand production and Parseval theorem, develops a system to monitor the sand content.Method:The main problem of designing the mechanical structure and matching layer for sand sensor is introduced. Furthermore a contactless Doppler ultrasonic method is used to develop sand amount detection system‚ finally the system measurement accuracy is calibrated by the developed calibration system.Conclusion:The sand production computation model can describe the relationship between sand monitor output and sand amount; compute the oil sand carrying ratio. The sand sensor is installed on the outside of pipe, not directly contacted with the sand particles. Measurement accuracy of the sand production is higher than the same type instrument.

scholarly journals Detection of Legionella DNA by PCR of whole-blood samples in a mouse model

2003 ◽  
Vol 52 (4) ◽  
pp. 325-329 ◽  
Author(s):  
S. Aoki ◽  
Y. Hirakata ◽  
Y. Miyazaki ◽  
K. Izumikawa ◽  
K. Yanagihara ◽  
...  
Keyword(s):  
Mouse Model ◽  
Legionella Pneumophila ◽  
Detection System ◽  
Lavage Fluid ◽  
Rrna Gene ◽  
Blood Samples ◽  
Non Invasive ◽  
Invasive Method ◽  
Dna Fragment ◽  
Legionella Micdadei

A detection system for Legionella DNA in blood samples based on the PCR was developed and evaluated in A/J mice with experimentally induced Legionella pneumonia. Primers were designed to amplify a 106 bp DNA fragment of the 16S rRNA gene specific to Legionella species. The PCR system could detect clinically relevant Legionella species including Legionella pneumophila, Legionella micdadei, Legionella bozemanae, Legionella dumoffii, Legionella longbeachae, Legionella gormanii and Legionella jordanis. The sensitivity of the PCR system was 20 fg extracted DNA. In the mouse model, the blood PCR was compared with results obtained by PCR on bronchoalveolar lavage fluid (BALF) samples, cultures of blood and BALF and detection of Legionella urinary antigen. Blood PCR was positive until 8 days after infection, while BALF PCR became negative on day 4. These results indicate that PCR using blood samples may be a useful, convenient and non-invasive method for the diagnosis of Legionella pneumonia.

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